Anyone on Letrozole?

[rubywoo24]

Hi everyone

I have been prescribed 3 cycles of Letrozole and I have just started AF after a very very long few months. So quite excited to finally getting things going!
We're currently away and I do have my medication with me but not the leaflet that came with it. So just want to double check that I am taking it correctly:

• do I count tomorrow as CD1 as AF only started at 9.30pm today
• is there a specific time that I have to take the tablets, I think night time is recommended?
• do I take both tablets together?

Any other help or advice would be much appreciated!

He loved it!!!! I'm so so pleased he was in there for way over hour half but he said it felt so good just to chat too as well as the treatment and he fell asleep for 45 mins until my phone call woke him up (I felt so bad but my worry head was on).

He even tipped her £20 because he said he felt amazing. He has agreed to go back every week but just for the 30 min session to save money @Sylva123 x

I’m sure it’s nothing to worry about @Sylva123 - 48 is still a good strong result. How does it compare to your previous levels (although I did read that results can vary from clinic to clinic based on the testing protocols if this is the first time you’ve had it done privately elsewhere)? I presume you still get rising progesterone on the cyclogest and it doesn’t just keep you at a constant level? Could be you caught it a bit early whilst it was still rising and it got even higher. Are you still managing to resist testing until tomorrow? The wait must be even more agonising this cycle. I’m keeping my fingers crossed for you x

@LongtermTTC yes I've had it done there twice before. Once it was 7 and another time it was 12. At the hospital it's been no higher than 21. So it's my first time over the magic 30 point. I think I might have tested a day late, which is making me think I'm not pregnant because someone on the clomid thread (back when I was on that) got her BFP the month that her progesterone was crazy high. I don't know about rising progesterone actually - that's a good question. I've never had problems ovulating, my problem has always been not producing the progesterone so maybe my body is still not producing any and the cyclogest is working hard to boost it up to 48... And maybe that's enough?

Yes I'm still resisting testing... Weirdly this has been the easiest TWW for me and I think sadly it's because I've stopped believing it can ever happen. I honestly don't think I'll ever see that positive test and I've started wondering what an alternate life would be like without kids. It's not the life I want and I used to truly believe this would work out in the end, but I'm slowly thinking maybe it won't.

Have you tested???

This article is in the US measurement of ng/ml but the conversion rate is 1ng/ml = 3.18nmol/l. It says that first trimester pregnancy is between 11.2 to 90 ng/mL (35 to 286nmol/l) so 48 is still within what would be normal so early in a pregnancy so definitely enough. www.babymed.com/normal-and-low-progesterone-levels-after-ovulation-and-during-pregnancy

I know what you mean though about not getting your hopes up - my hubby is always so positive and hopeful and keeps telling me to stay positive but I told him, after 15 cycles with no joy I just can’t allow myself to get my hopes up only to be dashed every time, it would be too painful so is a self-preservation thing to hope for the best but assume the worst. I’m so sorry to hear that you’re struggling to see things working out. I keep joking with the hubby about how many nice holidays we’ll be able to afford if we can’t have kids to try and somehow find a silver lining to the possibility that it won’t work but it’s not fooling anyone, least of all me! Don’t be too tough on yourself, allow yourself to wallow and feel sorry for yourself a bit if you need to, it’s shitty and it’s totally understandable. Then, when you’ve allowed yourself to grieve for the life you fear you might not have, I’m sure you will pick yourself up, dig deep and keep going with whatever it takes. Us women are pretty resilient when we have to be! I hope Thursday gives you some comfort / hope but more than that I hope you get the BFP tomorrow.

I got my results back and got a 55 so FINALLY ovulated. Still BFN but ovulating is definitely the first step in the right direction so we will just have to try again next cycle.

Ooh that's great thank you. I saw that article but didn't know how to convert it to the UK way, thanks so much for sharing that! Isn't it amazing what we learn doing all this. That has given me some more hope. I'm on my 27th or 28th cycle now... I just never ever believed we'd still be here. I'm always of the belief that if you work hard enough at something it comes your way, but this has proven otherwise. It's hard bloody work and nothing seems to change!
Hard not to lose hope isn't it! But all we can do is keep going and keep throwing everything at it.
Oh yay 55 is great! Congrats for ovulating. Definitely the first major step in the right direction! Nice to see some movement in that direction I bet xx

Hi

That's so good you've both got hight levels. I got my results yesterday too - 45! So definitely ovulated.
Speaking to the GP tomorrow to discuss next steps seeing as the clinic is cancelled...

X

@unknownscot yay!!!! Good progesterone all round.

Any news on whats going on with that clinic yet? Must be causing you some stress

Ohhh
I'm so not clued up with progesterone at all, all I know mine was 25 last time but that doesn't sound good in comparison to yours lol. I was told anything over 20 means ovulation?

BFN today guys 😢😢😢. That's me out for another cycle (13dpo & period due tmw). Not even the faintest of faint faint lines. Just the blankest test in the world. Can't believe we've got to this all over again for another month of crazy hormones, un-spontaneous dtd and digging deep for some more hope. Gutted! How are you all doing?

Oh @Sylva123x I'm so sorry 😭😭😭 will it now be your third cycle? I'm so sure I'm out this month and I'm so so poorly which I've read that doesn't help too :-( xx

Yes @Carleyxo ive done one on clomid & two on letrozole now. Consultant tmw who is going to say it's IVF time, so I've started looking at moving house today. I still have two more packs of letrozole in the cupboard so can try another 2 times whilst we move and go through all the initial appts for IVF. If my OH agrees to it - it feels like he's starting to get cold feet, which I understand. It's been over 2 years now and he's getting tired of it all. He's started saying he's happy with it being just us now...
Oh gosh you're still ill. That's such bad timing. What cycle day are you? I hope being ill hasn't impacted it. Maybe it's made you rest a bit, which is good for it all. Get well soon xx

Oh it's so bloody unfair for you that you can't even have one IVF round. Remind me aswell both your tests were normal weren't they? So no reason for it not to work?

Do house prices differ a lot to where you would move to? It's good you don't have to be there a minimum time though before IVF. Have you looked into IVF abroad at all? @Sylva123

It sucks I'm never ever poorly either! I've take the day off today because the fever is so bad x

@Carleyxo yes so far everything has been totally normal apart from having low progesterone. And we're dtd every other day and then a bit more around peak times. I don't understand why it's not happening for us. I spoke to some people about IVF abroad but I don't think it's for me - I think I'd really stress about it if I had to travel abroad somewhere new as well as go through all the treatment & keep it a secret. It looks like lots of people do it and do well from it though, maybe I should read more about it. Is that what you might do if you end up in that path?
We're renting (trying to save for a deposit to buy but not getting very far!) so it looks like rent is around the same price or just slightly higher. I did some sums yesterday and I think we can just about afford the move.

How long have you been unwell now? Is your OH past the worst of it? Hope it passes soon. And hope you have a nice restful day getting well. I got sick recently and bought some manuka honey (it cost a fortune at £20 😲) but it really helped me to get better. (This is why I can't afford IVF lol!) Xx

Oh, I’m so sorry @Sylva123. I got my AF this morning so that’s me out this cycle too. Was literally just about to do a test as based on my usual 10 day luteal phase I was 4 days late so despite BFN at the weekend I’d got my hopes up somewhat. Trying to take the positives from it but allowing myself to feel sorry for myself today (and going to treat myself to a nice big glass of wine later!) then will pick myself up again tomorrow. I hope you find some small way of treating yourself today too.

I wouldn’t read too much into what your OH says just yet - it could just be his way of trying to reassure you that you’ll be ok if it doesn’t happen and/or trying to convince himself of it. If you’ve got the letrozole I guess there’s no harm in trying a couple more months instead of always wondering what if? See what the consultant says tomorrow, give yourself some time to digest it and have a proper discussion with OH about next steps and IVF. Is a big decision to uproot your life and spend so much money, but then it’s an even bigger decision to give up on your dream - this “subfertility” stuff really is miserable and heartbreaking. x

@carleyxo sorry to hear you’re not feeling well, you’re not out until you’re out though so take it easy, look after yourself and fingers crossed for you 🤞x

@unknownscot - congrats on the progesterone results, how are things going with the clinic? x

Oh no @longtermttc. I'm so sorry about AF. Especially after the hope of it coming so much later than normal. God its so disappointing isn't it. It never gets any easier! The hope is a killer sometimes. Good plan on giving yourself the day to feel it and having a nice treat later on. I've got yoga tonight but I'm looking at finding a cheap spa day for the weekend - I'm craving a hot tub and sauna and I've stayed away from all that for so long because of all this through fear it would harm things. Feeling the need for a pamper before we get back on the horse.
Are you starting round 3 tmw? Sorry I can't remember how many letrozole rounds you've had. Hope you have a gentle day. I haven't managed to get out of bed yet but have a conference call at 10....
Gonna drag myself out for a walk and maybe a bit of cake :-)
Gentle days to you & Carley

Ok that's a lot easier than selling and buying though.

I know what you mean about abroad being stressful I'm not 100% sure how I feel about it except being soooooo much cheaper. On that podcast I was listening to a couple did it abroad and said it was amazing. Although I looked into it locally like someone suggested about the refund option and it starts from £7k and you get a partial refund if it doesn't work and they also offer a option for unlimited IVF for 2 years which is from £9k - obviously I'm sure it's much more than the "from" figure but will be interested to see how much.

I've been unwell since Sunday :-( Monday and yesterday I started feeling better and was in work yesterday and then today hit me bad so I'm off work. James is much better and went back to work as normal - he was off Wednesday for my bday so rested but was back in work Thursday. I'm sure I've got it much worse haha. I LOVE Manuka honey - you sound like me I'm always buying expensive options of random things 😂
I hope the appointment tomorrow goes ok though, what time is it?

Oh @LongtermTTC I'm so sorry it came 😩 definitely a nice treat tonight for you. How many more rounds do you have?

Oh gosh @Sylva123 a spa day treat sounds perfect! We can't deprive ourselves from everything can we.

Hi all, been really busy at work (and sad about bfn!) so need to catch up properly, but really sorry for the bfns. Sounds like there’s a few of us at similar places in our cycles. Hope everyone is doing ok. Will catch up later.

Well guys I managed to get a hold of the consultants secretary and she has no idea why the clinic had been on hold or cancelled.
She's going to look into it more for me and call me tomorrow.
I said I'd be happy to attend any hospital that the consultant works in and she said she'd try get me in to other clinics nearby with the same cons.

Fingers crossed.

The GP was really happy with progesterone levels so I'm glad the ovulation isn't so much of a worry now.

I also spoke to my manager today and explained things a little. He was actually very good and was understanding. He said "we will support you through this and understand the need for short notice appointments"
It's such a change from before!

@unknownscot that's amazing that your manager is being so supportive. That's absolutely lovely. What a relief to have it out in the open I bet. Half of the stress is trying to do it all in secret.

Hope they're able to get you into another clinic soon

@Carleyxo yes haha, got to love the manuka honey! And yes I'm always trying the next random health thing. I've got stocks of every kind of tea you can imagine in the cupboard at the moment. How are you feeling now? Hope it's passing and you're starting to feel better.

I'm going to enquire about medical loans as apparently theyre a thing that people can use for IVF.

My appt with the consultant is 12.15 tmw. Any pointers on what I should be asking? Last time it felt really rushed so I want to make sure I make good use of it.

I guess I'll just be asking what our options are now, what he believes will be our best shot, whether I'll continue to get monitored for my final two rounds. Maybe see if he'll increase the letrozole and progesterone doses or ask if that will help at all. Dreading it really cos it'll all feel real tmw. The Feb appt was always going to be the end of the line before IVF. February was never meant to arrive!!!!

@Sylva123
Is someone going with you tomorrow? My husband can't make some appointments so I always try have someone else with me cause you're right, it's a blur!
Wishing you all the luck for tomorrow. Speak through options and see what's available and timescales etc.
I hope you manage to get monitored for the remaining letrozole you have xx

Good luck today @Sylva123, I’ll be thinking of you. Just make sure you write a list of everything you want to ask, there’s always a lot to take in so it’s easy to forget things you meant to ask. xx

Thinking of you @Sylva123x I think all the questions you mentioned to us yday are good to ask :) let us know how it goes.

I'm still poorly off work :-( x

I got a clinic day for the other hospital in Glasgow. I'm so happy.

It's still when my husband is offshore but better than no clinic!