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Anyone on Letrozole?

1000 replies

rubywoo24 · 25/08/2019 21:46

Hi everyone

I have been prescribed 3 cycles of Letrozole and I have just started AF after a very very long few months. So quite excited to finally getting things going!
We're currently away and I do have my medication with me but not the leaflet that came with it. So just want to double check that I am taking it correctly:

  • do I count tomorrow as CD1 as AF only started at 9.30pm today
  • is there a specific time that I have to take the tablets, I think night time is recommended?
  • do I take both tablets together?

Any other help or advice would be much appreciated!

OP posts:
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Sylva123 · 31/01/2020 22:30

Your reflexologist sounds really good! I really hope you do ovulate. I know it's more money to spend out, but Ovusense was helpful for me to confirm I ovulated cos it was so accurate with the temperatures. Although I'm not sure if the letrozole messes all that up though, it might stop it being accurate. I've stopped using it now cos of the progesterone. All you can do is what you've been doing - you're doing so many good things for it to happen. And remember what the psychic person said 🤞🤞🤞

Carleyxo · 31/01/2020 22:46

You're so right I keep thinking of what she said and hope it's right. We had a bit of a argument tonight which ended up tears (we very rarely argue at all) he shouted and said that he feels shit and don't try and remind him this is his fault (all I said was all I've ever wanted isn't happening - never ever implied him)

He's obviously referring to the bad SA, he swore and stormed out (he's never ever done that before)

It's becoming so unbearable.

What's baffling is It's weird how the purple CB was flashing but the monitor and the cheapies said negative @Sylva123x

Sylva123 · 31/01/2020 23:04

@Carleyxo I'm so sorry - it's so unbearable. Me and my OH never used to argue but we have terrible ones now - everything is just so heightened and emotional all the time. No wonder you're having a few more fall outs than normal. It's the thing you want most in the world, and he's really sensitive thinking that he's the reason you can't get it. It's a horrible situation that no couple could get through without the odd tears. And it's the only thing you think about all the time. It's so hard.
We had a fight the other night that ended in tears. It's cos you both care so much. It doesn't make it any easier though does it. It's so painful. Is he back now and have u made up?
It's so confusing with the opks. Was it your first wee of the day? Sorry for being gross

Carleyxo · 31/01/2020 23:07

You are literally so right it's so hard and constant reminders everywhere

He sent me a really sad text after because gym is what keeps us mental health steady so I completely get it I really do but it's so hard!! He's finding it so hard that he could be the reason and that must be destroying. He's just coming home now apparently so we will see what he's like.

The monitor was the first wee which was negative but the stick was midday x

Sylva123 · 31/01/2020 23:43

@Carleyxo it really is so hard. I totally get it. Also you start off with such hope don't you - I remember when we started TTC and we were all giggly and excited thinking it'll be this amazing thing that'll happen so quickly and then it just slowly dawns on you that something's wrong and it becomes everything, and the total opposite to how it was at the start. It's sad that something so lovely gets turned into something so tense and high pressure and genuinely bloody sad. Hope you're alright later on. It's the worst when you fall out cos you're in it together, but sometimes I feel so far from my OH in all this and cos the problem is with me I do feel to blame all the time, like I'm letting him down. Your OH might feel a bit of that as well even though it's not his fault, it's just bad luck with our bodies.

God I don't get those opks at all. Maybe the LH rise was in the afternoon and u caught it then or maybe it's on the blink . Tmw will hopefully give u peace of mind

Carleyxo · 01/02/2020 07:41

It completely and utterly takes the magic out of it all doesn't it.
I never thought I would be in this position, life certainly throws hurdles at you. He still hasn't spoke to me and is getting ready for work now.

I'm currently doing a monitor test and a stick test out of the same wee - first of the day.

The monitor says it looks for oestrogen rise
Or LH surge and has finally come back high and the stick is still flashing! We obviously didn't dtd last night so hoping it won't effect it. Will try tonight tomorrow and next day @Sylva123

Carleyxo · 01/02/2020 07:42

Just realised got to wait for the peak so I could just ovulated a lot later this month who knows @Sylva123 x

AfterGlow87 · 01/02/2020 12:45

Hope you’re ok @Carleyxo! My husband stressed with work and we’re snapping at each other all week. I ovulated on Thursday I think so the added pressure of having to time everything not great either. We’ve tried to do it every 2 days from day 11 to 18 this month, who knew TTC could be so unromantic 😂

HarrietM87 · 01/02/2020 14:14

Hello, really pleased I’ve found this thread! On a few ttc ones on the conception board but people don’t really understand! I have recurrent miscarriages and need steroids from ovulation to maintain a pregnancy. My dr offers letrozole plus a trigger shot so you can time the meds perfectly, even if you ovulate by yourself. I conceived my son through this in 2018 after 3 mcs, then had another mc this summer (unplanned pregnancy so didn’t take the meds). This is my second cycle on letrozole and I’m 8dpo today. Not feeling very hopeful though. I’m also on cyclogest which gives me pregnancy like symptoms so can’t even symptom spot!

Sylva123 · 01/02/2020 15:37

Hiya @HarrietM87 and welcome! I'm 9dpo and also on cyclogest, trigger shot & letrozole. Such a mad cocktail isn't it - I've got nausea, really swollen & sore boobs and mad dreams but I know it's just the cyclogest as I've had it all before without getting a BFP.
I hope it works okay for you this time. Are you getting scans and is it NHS or private? Hope you're coping ok with it all

Sylva123 · 01/02/2020 15:38

@Carleyxo that's good that you've still got the peak to come. Hopefully you and OH will have time to make up and dtd. It's so weird how sometimes were ovulating super early and sometimes later. I prefer later cos at least you can get more dtd in beforehand!

Sylva123 · 01/02/2020 15:39

Also@harrietM87 I'm so sorry to read of your miscarriages x

HarrietM87 · 01/02/2020 15:39

Hi @Sylva123 yes I have a scan at Cd10-12 to check on follicles. Had 2 x 20mm this time so triggered then and there. With my son I had just one follicle at 18mm so goes to show you only need one. When are you testing? I have to test on Monday even though 10dpo is so early.

Carleyxo · 01/02/2020 17:27

Welcome @HarrietM87 and I apologise in advance for my mood rants I've been having recently 😂

@Sylva123x I hope so, do you think I should leave the tests for today or test again tonight? X

Sylva123 · 01/02/2020 17:40

@Carleyxo hm I don't know, what do u think will make u feel better? I think you're allowed to start testing more than once a day on Clearblue once you've got your flashy so I guess nothing to lose??? Unless it'll stress u out and in that case I reckon just leave it til tmw so you can focus on having a nice evening instead?

Sylva123 · 01/02/2020 17:41

The tests can stress me about a bit when I don't understand what they're doing?

Carleyxo · 01/02/2020 17:46

I think you're right @Sylva123 and actually if we dtd tonight it won't matter what the test says so I'll just wait till tomorrow and it saves using a test too x

Sylva123 · 01/02/2020 17:46

@HarrietM87 how come they told you to start testing so early? I'm not going to test til Wednesday or Thursday cos I'm scared of having a false positive if the HCG is still in the system. Will Monday be 14 days after your shot? Exciting! Good luck

Sylva123 · 01/02/2020 17:50

Yeah it's hard isn't it. I get fixated on the tests cos its the one bit of info we have! But you're still gonna dtd despite what it says so yeah let yourself relax and enjoy the night maybe. I wish they gave scans every month to confirm ovulation. Would take so much guess work out. X

HarrietM87 · 01/02/2020 18:06

@Sylva123 I have to test at 10dpo because I’m only meant to take the steroids for 10 days and stop if I’m not pregnant. If i get a bfn I’m supposed to keep testing every day until AF and restart the steroids if I get a bfp later. I got a really faint line from the trigger last cycle at 9dpo but it was gone by 10dpo. 10dpo is 12 days after the trigger shot. Do you get follicle checking scans?

Carleyxo · 01/02/2020 18:48

Yes me too so you know it's working. When's your next scan or what's the update? @Sylva123 x

Sylva123 · 01/02/2020 19:40

Oh crikey @HarrietM87 so much to think about isn't it. Let us know how the test goes Monday. Yes I was lucky this month I got lots of scans before ovulation and then the trigger so I can feel confident that I did ovulate this month (I hope!) even though the opks were negative but I know not everyone's been that lucky with the scans and I've definitely had some months flying solo with just the opks to go by. I don't get scans after ovulation though. Just before.

@Carleyxo I see the consultant on Thursday - this is the appt where he tells me that the letrozole hasnt worked and it's time for IVF :-(. I remember when we booked this appointment months ago and we thought we'd be pregnant by now... But here we are. I do have two more rounds of pills so I'll use them up whilst I sort out going private. You never know... We could still get lucky. I'll do my preg test on wednesday 🤞

Carleyxo · 01/02/2020 19:46

I have all my fingers crossed for you and two more goes for you is good! How much is it private?

We have one more month left after period comes and I get the impression she would prescribe anymore (that would mean we had three months worth)

Period is due on the 14th Feb but may be late seeing as I ovulate later this month as I was due to ovulate Wednesday gone @Sylva123 x

Sylva123 · 01/02/2020 20:24

Oh no a valentine's period :-(

But yeah it might be later now you've ovulated later. Is your luteal phase always the same? Mine varies but I think most people's stay the same. Remind me, what does it mean for you next? Is it straight into IVF as well? It terrifies me to be honest. This has already been so hard. Letrozole has to work for one of us on here!

Going private is going to cost an absolute bomb for IVF. It's terrifying. One thread on here said most people pay around £35k in the end. We're talking about moving house to be in an area that fund 2 rounds, because we just don't have that kind of money. Let's hope letrozole does the trick before all that 🤞. Dreading the consultant appt on Thurs TBH cos that's the start of all the big scary conversations.

Sylva123 · 01/02/2020 20:29

PS @Carleyxo did you guys make up? Me and my OH just fell out after I got home from 3 nights away. He said something about his sperm being fine, insinuating that I'm the problem... And as our fertility problems are "unexplained" I got upset trying to explain that my eggs are "fine" too - but for whatever reason it's just not working for us and we BOTH have to keep healthy and try our best. It's both of our issue regardless of whose body is doing what. Argh I hate this!

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