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Anyone on Letrozole?

1000 replies

rubywoo24 · 25/08/2019 21:46

Hi everyone

I have been prescribed 3 cycles of Letrozole and I have just started AF after a very very long few months. So quite excited to finally getting things going!
We're currently away and I do have my medication with me but not the leaflet that came with it. So just want to double check that I am taking it correctly:

  • do I count tomorrow as CD1 as AF only started at 9.30pm today
  • is there a specific time that I have to take the tablets, I think night time is recommended?
  • do I take both tablets together?

Any other help or advice would be much appreciated!

OP posts:
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8
EveMD77 · 10/01/2020 15:17

Aww Sylva it sucks! Hang in there, debt is just another thing to stress you out and that won't hep either xx

i still don't know the results of my first 2 21 day bloods. My consultant changed inbetween my first appointment and my bloods and no one seems to know where the result went I dont think i ovulated though as i had a 21 day period and was still on it when i had my bloods done. last month and this month my periods have been ultra heavy to start the lightened and been finished within 7 days which is promising. But stupid me took an extra thyroxine tablet instead of letrozole on day 2 so i started them a day late this month FFS . Have an appointment with consultant on monday so we'll see how im doing i guess. i got darker lines on the OPK last month but thats still negative and i didn't get pregnant. Gotta say the mood swings and headaches during my periods are fierce! good thing hubby is patient. Hows everyone else getting on? has anyone conceived that was trying on this thread? x

Carleyxo · 10/01/2020 17:48

Oh @Sylva123x I'm so sorry 😢😢😢 is there any chance you could of ovulated earlier? Do you do pregnancy tests before taking letrozole? Sending you lots of hugs xx

Sylva123 · 10/01/2020 19:24

I did about a billion preg tests before I started because I was in disbelief that the clomid didn't work. I kept testing testing testing and it hadn't worked. Then the period came and I started the letrozole. So I'll wait for full flow to come and then I'll try it for the second round. I'll beg for the trigger shot again this time.

I started ov testing on day 9 and have had negatives since then, all the way up to day 21. Do you think I could have ovulated as early as day 8?

Carleyxo · 10/01/2020 22:15

I don't know about whilst on letrozole or clomid but I have a friend who ovulates straight after her period - like 6/7 so I wouldn't rule it out but I'm not sure how common it is. Definitely ask for the trigger shot it's so bizarre that you didn't ovulate, did you have sex earlier in the cycle? @Sylva123 x

Sylva123 · 11/01/2020 09:48

@Carleyxo that's good to know about your friend. I'm wondering if that is what happened to me this time. I'll start ovulation testing much earlier next time around. Unfortunately we started on day 9 cos we were at our family's over Xmas and couldn't start any earlier. Calling my doc first thing on Monday to ask for her advice!
I'm not even out of bed yet this morning. I know as soon as I go to the loo full AF will be here and I don't want it!!!

CCPP · 11/01/2020 10:28

@sylva123 awe I'm so sorry xxx how many times a day did u check for ovulation? I read ppl should do it in morning (not using first morning pee) and evening so you might have missed the LH surge using the opk? Could this possibly be implantation bleeding or is it AF?

Carleyxo · 11/01/2020 10:45

Really feel for you :( it will be interesting to hear what she says. What ovulation tests were you using? @Sylva123

Sylva123 · 11/01/2020 12:18

It's definitely AF @CCPP and @Carleyxo 😢. It's really heavy & painful now.

I was testing with Clearblue digital and the Amazon cheap ones. I used both in the morning and then the cheap ones in the afternoon / evening every day since cd9 until yesterday, so I'm sure I didn't miss the peak unless I missed it before day 9. I guess I just didn't ovulate or I ovulated super early. But to have such a short cycle, just 21 days, has really freaked me out. I'm trying to stay positive for the next cycle but it's just getting me down. Not just all the vitamins, all the dtd on the right days, the hope and the disappointment, but also having to keep lying to people at work about why I'm cancelling meetings at short notice (to go to my hospital appts) and all of that the goes along with it all. You know? I'm honestly feeling like such a failure. I'm so down. Like all the good things in my life I don't care about, I just want this.
And I'm terrified of IVF being the next step. Arghhhh.
How are you both??? Carley how are things at home?

unknownscot · 11/01/2020 12:51

I have a six month supply so got another two rounds of letrozole to go. But my husband will be working away as I ovulate so no hope in hell I'll get pregnant.
That in itself is causing me stress and feel so down about it.

I know my mum is caring and trying to help but messaging me to tell me to watch the "conception plan" on this morning wasn't beneficial when part of the reason why I won't fall pregnant is because husband is away while I ovulate for the next two cycles!!!!

Also ladies, my consultant said not to use the home ovulation kits as they aren't 100% and get you stressed out. Just some food for thought x

Carleyxo · 11/01/2020 14:37

@Sylva123 I completely get it I promise I really do, sending a hug your way. I have no idea so I'm just speculating but IMO a 21 day cycle may imply you could of ovulated earlier and just mossed it? I'm sorry to say it but I think maybe that could of happened? Looking at flo when my cycles were 26 days I ovulated on day 11/12? Xx

Carleyxo · 11/01/2020 16:18

Are you ok @Sylva123 xx

Sylva123 · 11/01/2020 16:28

Thanks @Carleyxo. I'm not doing great today. I know it's the hormones jumbled up with everything but I just can't stop crying. I feel so defeated. I'm just exhausted and upset by it all. I met a friend for a cuppa and I just felt like I didn't care about anything we were talking about. And it's not her fault, but she can't understand where I'm at. She's never wanted kids. I hadn't seen her since last autumn and I thought going out would help, but I feel even more isolated!
Thanks for the hug and for saying you get it. It does help. I'm sure I'll feel better tmw and will be ready to do it all again. Just today I'm feeling sorry for myself

Carleyxo · 11/01/2020 17:32

I'm wondering if the hormones kick in at a certain point on letrozole? I hope the pain eases, tomorrow is a new day, I've got a much better mind frame today so I'm hoping you will too. I'm planning on seeing a medium soon x

Sylva123 · 11/01/2020 19:31

I think my mood is always wonky around my period time, but I also think letrozole keeps working throughout the month even when you're not taking it. I think those 5 pills start a chain reaction which alters the hormones all through the cycle. I'm sure I read that. I always get super affected by hormone changes tho, do you? So, so glad to hear you're in a better mind frame today. It goes so up and down doesn't it.

Ooh that'll be interesting to see what the medium says. Have you been to one before???

Carleyxo · 11/01/2020 22:04

You poor thing 😢 bloody hormones
I'm not always affected by them to be honest but at the same time I also get no side effects which is a tad annoying

I have but. A year ago and she said I would be with a. Baby by the end of this year so I'll be interested to see if it's changed. I was recommended a good one today so may try her x

Carleyxo · 12/01/2020 21:26

How is everyone x

Sylva123 · 13/01/2020 17:30

Yeah ok today @Carleyxo. Being at work definitely helps take the mind off it all. I got through to the hospital and got a scan appt for tmw thank goodness, so at least I'll be closely monitored this cycle.

How are you?? The thing you said about your medium reminds me of an episode of Jay Shettys podcast I heard the other day. A woman on there got told she'd have her baby by March. She didn't, but she conceived in March.

Carleyxo · 13/01/2020 21:45

On thank goodness for that! I hope tomorrow goes okay for you, what time is it? Glad they will be monitoring you more now. I'm much better thank you I will be due on the 24th so a waiting game now. The medium was good she said I would be pregnant by May so it will be interesting to see @Sylva123 x

Sylva123 · 14/01/2020 13:59

Oh you already saw the medium! That's exciting @Carleyxo. I so hope it comes true for you. I wish I had a crystal ball - I'd relax a bit if I could be sure it's going to have a happy ending with us getting a family in the end.

So I had my appt and she said you can ovulate really early on letrozole & she thinks that's what happened to me last month. It looks like it's happening again - I'm only on day 4 and she can see two big-ish follicles. She's so good - she's booked me in to see her again Friday to see how the follicles are growing. It's likely I'll ovulate on day 7 which is crazy. I didn't start testing and dtd til day 9 last month. And we dtd SO MUCH but it was all too late! Oh well. I feel reassured that she's keeping such a close eye. It's a good thing to know about the early ovulation. I'm going to start dtd tonight.

How are you feeling about the two week wait? What things are you doing to stay calm and sane? Xx

Carleyxo · 14/01/2020 14:19

I know it's nice to be reassured.

Oh wow that's crazy isn't it but gosh I'm so so so relieved for you that they're monitoring you close! You wish they would just pre warn you about this stuff instead of just giving it to you.
Two big follicles is good it will be good to see how they look Friday :) my OH has got a semen analysis retest on Friday so will be interested to see if all these vitamins and no hot baths have made a difference @Sylva123 x

Sylva123 · 14/01/2020 14:34

I wish so much they'd told me it was possible to ovulate that early - I would have began testing earlier! I feel like it was a totally wasted cycle but at least we've learnt something. And we're getting on it this week now. Potentially only 3 days til ovulation!

Oh good luck for you OH. My OH had slowish sperm (forgot the technical language) on his first test but it was much better the second test. From what I remember he has lots of the stuff, but it's a bit slow and confused about where to go!
Luckily our bath is broken at the moment so not hot baths for a month. Let us know how it goes and what vitamins your OH tried & whether it made a difference. Are you nervous about it?
My step mum swore by mediums by the way. She said they predicted her two daughters and she conceived both of them whilst on contraceptives. They were both freak pregnancies. Sods law isn't it .. those that don't want to get pregnant get pregnant, those of us that do don't!

Carleyxo · 14/01/2020 17:08

I literally find it ridiculous how little Info they give you! Definitely get on it and let us know when you get your positive ...

My OH count was really high but morphology which is the shape of them was 2% and normal is 3% + so he's cut out baths and also taking every vitamin going so it will be so interesting to see if it has improved or not - I hope it has!

I do hope so that would be amazing she said by April/May time so that would mean after I finish letrozole as I only have it until March time @Sylva123 x

unknownscot · 14/01/2020 22:24

@Sylva123 are you going through nhs ? How come you got scans so quickly?

Sylva123 · 15/01/2020 08:47

Yes @unknownscot I'm with the NHS. To be honest it has been a nightmare up til now. We were on the waiting list for a year, then they lost us in the system and we had to start from scratch, then the first consultant was absolutely horrible to us but now we've got this amazing Dr who is really on it - she squeezed me in yesterday because something wasn't right with the last cycle and now she's squeezing me in again on Friday. She tends to give me weekly cycle monitoring, which is incredible given that she's the only fertility doctor in the whole hospital. When she's off there's no on else. It's all mad really but it's just because she's such an amazing doctor, she's trying her best to support us all despite the state of the hospital (which is falling apart cos of all the cuts to the NHS). I don't think she ever takes a lunch break and there's always a queue to see her. I told her yesterday how lucky I felt because I know others on the NHS not getting as closely monitored. I think it's just luck who you get isn't it.

Sylva123 · 15/01/2020 08:56

By the way @Carleyxo I've been using the "Fertility From The Soul" guided meditations on YouTube. I pop them on my headphones when I go to bed and fall asleep listening to them. They're quite nice and I have been sleeping so well. Last month I had that terrible insomnia & bad dreams on letrozole but haven't had that at all this time .

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