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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Anyone starting IVF? Join me (5)

505 replies

waitingimpatient · 10/02/2016 21:11

I don't think anyone has started the new thread yet? Apologies if so and ignore this one if its already been done

I'm hoping by the end of this thread I'll be waiting and impatient for a new arrival Smile fingers crossed

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waitingimpatient · 13/03/2016 21:19

They just seemed so sure that morning from the scan that cetrotide was not needed.....a few hours later after blood results they were insisting I started it immediately so I wondered if that had an impact

It's hard to know and I feel like I'm constantly analysing it all, looking for answers, wondering why things didn't work, researching things etc etc

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bananafish81 · 14/03/2016 11:43

10w scan this morning showed our baby has gone. Missed miscarriage Sad Saw a beautiful heartbeat at 7+1 and 8+5 but baby measured 9+3 so it died mid/late last week. Utterly heartbroken.

LHReturns · 14/03/2016 11:57

Banana I am absolutely sorry to the bottom of my heart for you. Right now there are no words you need or want - just total sympathy and condolences.

Fractiousfractions · 14/03/2016 12:10

This reply has been deleted

Message withdrawn at poster's request.

Everhopeful76 · 14/03/2016 12:36

Banana I am so very sorry to hear this sad news. Rest in peace little angel.
Sending love and support today and in the coming days xxx

waitingimpatient · 14/03/2016 14:15

banana I'm so so sorry this has happened to you. I wish I could just give you a huge hug. Lots of love to you at this awful time xxxx

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Blue2014 · 14/03/2016 15:00

Banana - you helped me on another thread so I'm delurking to send all my love to you, I'm so so sorry this has happened for you, my thoughts are with you x

Indecisivejo · 14/03/2016 16:33

Banana I was just reading and saw your message and felt physically sick I'm absolutely gutted for you I could genuinely cry right now! I'm so very sorry, I don't even know you but really want to hug you so tight x

bananafish81 · 15/03/2016 00:20

Thanks ladies for all your messages of support. It means a lot.

Dr got me booked in as an emergency day case and did the ERPC early evening. Got his anaesthetist in specially. So unbelievably grateful to have been able to get it done quickly as I couldn't bear having to go home and wait, with my dead baby still inside me. It's done. I'm home now. Physically, I'm fine. Mostly I'm just numb. DH is utterly broken - we've sobbed and snotted all over each other.

Having the tissue testing done on the 'products of conception' to see if that will give us any answers, find out results and next steps in a few weeks when I see consultant for follow up.

Thanks again ladies xxx

LHReturns · 15/03/2016 05:50

Banana - I have posted this message on another thread but this is my regular thread so have re-posted it here as this is where I feel connected.

I just want to say again how very very sorry I am for the loss of your baby. I have loved following your recent success and details of how you dramatically increased your egg count and quality between two cycles.

You won't remember me as you help so many of us, but I am the one who is on holiday and utterly ignorant of what all this involves as my first time. I am 40 with one son, and desperate to have another baby.

It is you that got me focused on my process in a meaningful way, you who told me what to read, to eat, to drink, supplements to take, how to think about it....you who reassured me that my apparently plummeted AMH with an ok AFC does not have to be bad news. It is you that has engaged and motivated me and since then I have combed the threads for your wisdom and reassurance. I think you are a goddess and I hope to continue to follow your story to motherhood.

Thank you so much for helping me, and I reach out to you with great warmth while you and your DH understand your miscarriage. You deserve to be a mother and what a beautiful one you will be.

I started my 450iu Gonal F last night and will return from holiday to London for my first scan at the Lister in Friday. I hope I can continue to update you and learn from you once you feel ready to re-engage. I find your knowledge and outlook absolutely invaluable. X

waitingimpatient · 15/03/2016 06:39

Oh banana what a horrible day for you :(

I think 100% you did the right thing having the erpc so quickly. In sep 2008 I had a mmc but was sent away for 'conservative management' and didn't have an erpc till two weeks later. The wait was awful. Much much better to have the procedure done straight away.
I hope you are not feeling in any pain physically. Emotionally I know it is horrendously painful though and I can't stop thinking about you. Xx

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waitingimpatient · 15/03/2016 15:40

Had our follow up today. We are going to be doing another mild cycle in three months. ICSI this time rather than IVF

Also, they think the reason it failed this time was my very high TSH level. For some reason it had shot up hugely despite me still being on medication and having it checked 2 weeks before the FET it had more than doubled :( they said it probably affected implantation

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Shellster52 · 16/03/2016 01:42

I am lost for words banana. I felt numb as I read your post. I thought that once you saw the heartbeat and that things measured correctly, that you were on the home stretch and the chance of m/c was minuscule. My m/c after my 2nd last IVF cycle was very early on and although utterly devastating, I can't imagine what it must be like for you further in. I hope the tissue testing provides you with answers, but what an absolutely horrid process to have to go through. I am so sorry.

waiting, must be difficult having thyroid issues too - I had 7 embryos transferred to get my single pregnancy and found I had enough questions about what could have gone wrong, without adding an extra issue into the list of possibilities.

I hope your scan shows some reassurance LH that you still have several follicles growing just as your previous scan showed your body has the potential to do, and you can put that conflicting AMH result out of your mind as a worry that you will not respond well.

waitingimpatient · 16/03/2016 07:13

I'm just so annoyed but it's nobody's fault and in a way is helpful to have a reason for possible failure.
The clinic checked TSH a couple of weeks before FET cycle and then I asked again the day I had my first appt.....the level had actually gone down to 0.48 so they advised to reduce my Levothyroxine dose and repeat TSH on same day as hcg test. In the two weeks it shot up to 5.7?? So now I'm back in the original dose and I suppose at least I know to keep a close eye on it and not reduce the dose next time even if it is 0.something
I cried on the way home. I said to dh I feel like I was so close and the TSH level probably ruined it. All the medication and stinging cleans injections and all the time my TSH level was rising and probably stopping the embryo implanting. I also went home and stupidly ate rubbish too when for days I've religiously stuck to my healthy eating plan so today I'm starting again and forgetting about yesterday.
I was actually quite impressed with the follow up we went through all our questions and everything was explained. We are doing Icsi this time as they said last time not as many eggs fertilised as they would have Expected. They went through it all in detail so I feel reassured.

I will have an appt before the cycle in three months as they want to check that I don't have any cysts etc before going ahead and of course more regular TSH tests

banana I hope physically you are feeling ok. I know emotionally it is so so hard but in thinking of you xxx

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waitingimpatient · 16/03/2016 07:14

*clexane not cleans

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tillyann2013 · 16/03/2016 07:19

I am so sorry to read this banana, hope you are doing as well as can be expected.

LHReturns · 16/03/2016 07:38

Banana, still thinking about you. Please let us know how you are even if just a few words.

Waiting, while this must be unbelievably frustrating for you am I right that this means you are so so so close to nailing this? I don't know anything about TSH and what they can do next time to manage it better, but from reading your long and painful story it strikes me that you are bloody close to bringing all the variables together to create success. Your follow up sounds excellent and that you have a great stretch to get your supplements going through spring (I will join you!), and then a fresh summer go. Psychologically does it not feel good to have a strong hypothesis around what when wrong this time? Easy for me to say I am sure...

May I ask you all a couple of questions re the short antagonist cycle I have just started...?

  1. I started Gonal F 450iu on Monday night so have done just two injections. I feel absolutely NOTHING....is that typical after just two? When would I expect to bloat, or feel some aching etc?

I have not done any down regging.

  1. My baseline scan here in Maldives (on holiday) on Monday (day 3 of period) revealed 10 follicles, 5 on each side - is that normal baseline position? For a 40 year old remember....
  1. Talking to my consultant at Lister on email last night- about fact that my cycle is very regular but SHORT at just 23 days.

I fly back to London tomorrow (Thursday day time), so original plan is to go to Lister for scan on Friday morning, and start Cetrotide that night. This would be day 7 of my period and day 5 of Gonal F.

Last night she suggested I COULD start the Cetrotide one day earlier (tomorrow, Thursday night) due to my short cycle, just to 'be on the safe side'. But she says it is not really necessary and still thinks Friday will be soon enough. She is relaxed either way.

I have no problem with either approach but do all you experts have any advice? I assume as soon as I start the Cetrotide the follicle growth slows down, but equally it would be a disaster to ovulate too quickly due to my short cycle.

  1. Consultant also said last night that she 'expected' my EC to 'almost certainly' be before Easter but she would know more when I get back to London and start scanning.

While I would love to get this done before Easter, it seems fairly quick. Any thoughts on how long I might be stimming for (on granted very high dose of Gonal F) before I might hope to do EC? Does my naturally very short cycle speed up the process of follicle growth and maturity?

Any thoughts on any of the above questions would be so gratefully received!!

waitingimpatient · 16/03/2016 08:55

LH I did have symptoms the first day of gonal f but I think that's due to having pcos and being v sensitive to most medications. It is probably completely normal to have no symptoms though

10 follicles sounds quite good to me, but I'm not an expert. I had far too many all various sizes so I'm not sure what the 'normal' amount is but 10 sounds good to me !

Yes in regards to TSH level at least I know to keep a much closer eye on it and hopefully next time I can get everything perfect. In a way it's good to know what went wrong at least I can try to fix it

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Shellster52 · 16/03/2016 09:16

LH, others on here would report bloating and the like during the stim phase of IVF, but I felt absolutely nothing on all 11 of my IVF attempts. So I guess it varies from person to person but hopefully that reassures you in case your body is like mine - but my follicles still grew and I still (FINALLY) had success. I personally think 10 is a good start for a 40 year old! Again I guess it varies as I started with only 6-7 on my last few cycles at age 37 so to me having 10 at age 40 sounds great, while waiting with PCOS would probably start with a lot more. I am not sure about the best day to start Cetrotide and would hate to guess and for you to guided by my decision only for it to be wrong! I know waiting on here found her follicle sizes scattered once she started it and wondered if the Cetrotide was the cause or if it was just co-incidence. But I also chat to luci on the 'day 3 versus day 5 embryo transfer' thread whose Dr started her Cetrotide too late on a previous IVF cycle and it had to be cancelled which left her really resentful. What day do you naturally ovulate? Out of curiosity, I know you have had your AFC and AMH tested, but have you ever had your day 2/3 FSH levels tested?

waiting, it's so easy to look back in hindsight and wonder what if... LH had some beautiful words for banana and she words it really well for you too that hopefully you are putting all the pieces together and close to getting the stars aligned for next time. Like I said, this was my 7th embryo transfer that finally produced success.

Two were two celled day 2 embryos,
one was a top quality day two 4 celled embryo,
and the other 3 were all top quality day 3 embryos.

None of these resulted in a successful pregnancy and I don't have the TSH issues that you have. So it's impossible to say that the TSH level ruined it, although I can totally understand you feeling this way. But glad you are aware to monitor it in preparation. I too would do exactly the same as you. Feel like crap, eat junk (and worse - lots of alcohol) and then feel bad that I had ruined my eggs for my next attempt. People on here would tell me not to be so hard on myself and that I deserved a few days off after an IVF failure. So I understand how you feel, but now that I see it from an objective viewpoint, you really have been through the wringer and deserve a day off after an emotional consultation. Glad that they were thorough and you feel you are being looked after.

Shellster52 · 16/03/2016 09:16

banana, thinking of you xox

bananafish81 · 16/03/2016 16:22

Ladies thank you so so so very much for your beautiful messages of support, I am truly touched

(and LH of course I remember you!)

My Dr got me booked in as an emergency day case, so we found out at 10am, I was in theatre for an ERPC by 6pm and home by 10pm. So I was very very glad to have been able to get things sorted so quickly.

He was absolutely bereft and said it was the saddest part of his job. He stayed late to do my op, and got his anaesthetist in specially for the procedure, which I appreciated. He shared that his wife had had an ERPC when they had a miscarriage, which I was really touched he shared, as he wasn’t just showing sympathy as a kindly Dr, but could be truly empathetic having been on the other side of the fence.

Physically I am absolutely fine. Emotionally, obviously DH and I are devastated.

I personally find the best way for me to deal with things is to look ahead, so I am already thinking about next steps.

We're having the tissue testing done on the ‘products of conception’ to see if that will give us any answers: we will find out results and next steps in a few weeks when I see consultant for follow up

Hopefully it will show whether it was the seed (embryo), or if not then it was presumably the soil (me)

Unfortunately although having seen a heartbeat at 9 weeks, you think you are on the home stretch, but sadly that is simply not the case. I know far, far, far too many people who have suffered MMC who have lost their babies at around the same time. It is about this time that the placenta takes over, so it’s a bit of a make or break time. Although our beautiful 4AA blastocyst looked morphologically perfect, that doesn’t tell you anything about its chromosomal integrity. 70% of miscarriages happen because the embryo simply didn’t have the right genetic makeup to be able to become a person.

However, whether this embryo was OK or not, we don’t know which of the 4 frosties are duds and which are go-ers, which means potentially 4 failed FETs or miscarriages

I am not willing to play Russian Roulette with these embryos, to be brutally honest. We could hit the jackpot with the next frostie - or we might not

So regardless of the outcome of the tissue testing, I am minded to see about doing another fresh cycle, and if we are lucky enough to get a decent number of blasts like last time, to do PGS so that we can be sure of only putting back a chromosomally normal embryo. And keep the 4 frosties on the subs bench

If the embryo WAS chromosomally normal, then the issue was the soil (my body) and not the seed. So will discuss doing a lap or hysto to check out the uterine environment before we put anything else back. Although it's pretty unlikely to be something uterine, as we didn't have any issues with implantation - I got pregnant on my first transfer. I just didn't stay pregnant. So the issue doesn't seem to be with inability to implant.

We had talked last time about immunes treatment anyway. My Dr doesn’t find the Chicago tests reliable (as NK cells in your blood don’t necessarily tell you what’s going on in the uterus) and prefers to treat empirically for failed implantation or miscarriage. So I think we will almost certainly add in an immunes protocol next time (prednisolone, intralipids, clexane, aspirin, gestone) for a belt and braces approach.

My thyroid function was tested and was perfect, although we will definitely recheck it, as we don’t really want to leave any stone unturned.

But for now, I’m in the ‘PJs and pizza and chocolate and crying stage’

bananafish81 · 16/03/2016 17:05

LH I promise to reply to your questions too as I also had a baseline of 10 follies and was on short protocol of 450iu Gonal-F followed by Cetrotide. Reply to follow! Xx

waitingimpatient · 16/03/2016 21:24

banana your doctor sounds amazing. I'm so glad you have such great support and could get the Erpc done so quickly. I think psychologically that's really helpful as waiting after a mmc is like being in limbo so it's good you could get the procedure done the same day.
I've been thinking of you lots. Pjs pizza chocolate and crying is by far the best thing to be doing. Be kind to yourself, it takes time to comes to terms with it (I won't say time to 'get over' it as you never really do) but I found that once the Erpc is done and physical symptoms improve it gets easier day by day and it's good you are thinking of what to do next and hopefully the tests will provide some answers.

Sending you lots of love and healing Flowers

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LHReturns · 17/03/2016 03:40

Dearest Banana - it is so good to hear from you. You are clearly an icon of strength and positivity which is what will also make you successful in this story. Please do keep us informed as you emerge from this initial horrible dark cloud and let us know your next plan.

I would love your thoughts on my previous questions when you feel like it! I board a ten hour flight today (Thursday) at around 7am UK time so will be back early evening to read and respond. Especially keen to hear your thoughts on my question of whether I might inject the first Cetrotide tonight instead of tomorrow. I am leaning towards NOT currently. First scan tomorrow morning at Lister and feel not an ounce of pain around my pelvis - cannot believe a bunch of eggs are about to explode forth on day 6 of my cycle.

Day 4 on Gonal F today (so 3 evening injections done)...:still no recognisable side effects other than mild headache if I don't keep drinking water and - CHARMING - diarrhoea. Is that a side effect of Gonal F or could be just anxiety from all this? Travelling all day with the squits is every girl's DREAM.

Continue to feel better Banana, and thank you so much also to Waiting and Shellster for their thoughts. I am reading and re-reading all your posts and taking all of it onboard.

Speak in London. Now of course feeling nervous about tomorrow's scan....might need the loo again....

waitingimpatient · 17/03/2016 07:12

It may very well be the gonal f causing stomach issues LH as when I took it it was the only two weeks in years where I was going to the bathroom repeatedly (due to thyroid issues Iam always horribly constipated) so I think it does have some kind of 'laxative' effect!
I felt so much better though, it was an inconvenience but I honestly felt so much more comfortable each day !!! Then of course my ovaries got swollen so it sort of solved one issue only to cause another

I hope your flight is ok and that your holiday relaxed you

I'm back into my healthy eating plan and planning a nice brisk walk this morning. I'm feeling positive and hoping my increase in thyroid medication will start to kick in soon

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