Once my hCG is down to zero, we’re going in all guns blazing. Plan ‘throw the kitchen sink at it’ is going to be launched.
We’re leaving the frosties on the subs bench and going to try to get fresh embryos to do genetic testing
At the start of the stims cycle, we'll start me on thyroxine to get my TSH to under 2.
Stims wise, same as before, short protocol, starting dose 450iu Gonal-F, drop dose down depending on follicle growth. Rest of cycle as usual. Try to make eggs, collect eggs, try to make embryos, -except instead of doing a transfer, we will biopsy anything that makes it to day 5, send off the biopsies for PGS testing, and whack the embryos straight in the freezer, as the PGS results take 2-3 weeks to come back.
After period, we'll start me on oestrogen as if preparing for a FET, until the PGS results come back. Dr said we should aim for 4 euploid embryos, which realistically we ain’t gonna get in one cycle, so once results are back, we’re likely to convert the FET into another stims cycle (and treat the run up as oestrogen priming, which for a low-AMH-er is no bad thing!)
He normally recommends 3 months between fresh cycles - except for me, as I seem to do so well on stims, and I get better quantity and quality when piggy backing off the last lot (ovaries slightly stimulated gives me more follies in the starting block, and cumulative effect of oestrogen gives me better quality). So as long as my ovaries are looking OK, and I’m still up for going again, then we’ll crack on doing 2 stims cycles back to back.
So basically lather, rinse, repeat exactly as before. Try to make eggs, collect eggs, make embryos, biopsy anything that makes it to day 5, send off biopsies for testing, whack in freezer
Now obviously all this is predicated on the assumption I can make embryos and blasts like last time!!! Which I may not, if it was a fluke.
Hopefully we’ll then we’ll start a FET again after my period (so oestrogen pills and patches), but this time keep it as a FET. Whatever results from PGS, hopefully out of two batches we will have SOMETHING genetically normal to put back.
Then we really throw everything at it when it comes to transfer. Lubion (injectable progesterone) as well as cyclogest, intralipids infusion, prednisolone, aspirin and Clexane.
So hopefully we’re looking at either 2 cycles in 2 months (fresh+FET) or more likely 3 cycles in 3 months (fresh+fresh+FET)
Shit myself and hope for a BFP and that I don’t kill another baby.
Phew.