Assisted conception after recurrent miscarriage part 5

[Mel3062]

Hope this is right ladies ...

duggs are you out there somewhere? How are you doing??

Good luck with the melatonin Brown, it amazes me how we all keep going. What a resilient lot we are!

I stupidly did a test this morning even though not due to do official test until Monday! Of course it was completely negative but I was thinking after a bladticyst transfer would be a faint line by now........ guess will just have to be patient!

Thanks Ari.
No idea why I couldn't find that xx

Got results from lit and My friend says they are amazing they were 3.4 and 9.0 last time and now they're 51 and 92.8 and he likes them over 50 so fingers crossed to see what dr g says sat. Good luck pebbles. I lost the link thanks brown!! Waves to all xx

Good luck Ari hope your daughter is getting better. It sounds like the care in Athens is great.

pebbles can not blame you for testing early. The roller coaster is just rubbish

My cycles have still not returned post birth but when they do figure we will just go for it. Give it 6 months and then if no joy re evaluate. It is so difficult do not want to miss out on ds babyhood, and know how ttc takes over everything

Test

Hey peeps written a few posts but didn't show ? Been busy with new job. Planning on IVF with serum in May - heading there for hysteroscopy in April. Earliest I can get out there so just wishing time away again. Hope u ladies feeling ok? Pebbles routing for you...

Yey duggs good luck! Pebbles good luck for mon.
Been to see dr gorgy who said a lit booster would be better as it would last longer then just retest when preg.
Hubby's come away with more proxeed!
He suggested we try for 6 months. I need 3 lots of intralipids (1 every 4 weeks) not sure why I'm not having any for the remainder of the 6 months.
I'm having ivig when preg.
He didn't mention neopegen this time but he did at first meeting, wish I'd queried that.
I'm on clexane from day 7 ( never had that before it's always been on pos test?!)
Steroids have increased to 40 mg from day 7! As nk cells are high, no sleep!! Prof quenby recommended me to just have clexane and progesterone on positive test as something had caused high uterine cells but I guess that could of been the hydroxy or any other vit I was having!
I'm on progesterone too from after ovu that's new as that used to be after post test.
He's recommended I have dhea as amh is low.
I hope all this is ok to take with thyroxine!
All in all it sounds very rigorous! Is tinzerparin the same as claxane? I have that already?!

Hey Mel certainly throwing the book at this. Ivig I believe when pg does what lit does so no need for lit when pg. yes tinzaparin is a form of heparin so same as clexane a blood thinner. Progesterone from bfp seems increasingly common ARGC do so to apparently and helps implantation. Not sure about the nuepogen think you should email or call to clarify that point. 40mg pred same as dr S. I believe dr G is one of the if not the most thorough/aggressive approach to immunology after working alongside dr beer when he was alive so if this lot doesn't work on the immune side not sure what will. Just need a healthy embryo to come along now. What is proxeed for DH?

Thanks duggs, I'm going to see if my doc will prescribe them all for me though not sure about the clexane but I can ask!!
Just scared to take the tinzerparin as it's a diff name is that daft?! My rmc lady gave me that but from scan so don't think she'll approve. Lit would be cheaper than ivig :/
Yes I had progesterone from BFp before but now I'm to take it after ovul even though he doesn't think I have a progesterone prob, joy!
Not heard of clexane when trying before so that worries me abit.
Proxeed is an antidoxiant drink to help sperm as the fragmentation wasn't great- look it up on amazon he's had 2 months of it but dr g said about 4 x

Mel On the Clexane thing, Serum have you taking it a long time in the cycle before ovulation - I think about day 3 of your cycle or so. I think it's fairly standard procedure, I wouldn't worry.

Thanks ari that's reassuring x

Fab results Mel and good luck with ttc!

Nice to hear you are ok Duggs, tested this morning and got two negatives and the faintest of faint shadows on one and you had to really squint. Gutted as that was last go for us with my eggs, can't believe am never going to have my own child!!!! I think next step will be donor eggs at serum but prob won't be able to do it until summer as still trying to pay for last ivf.

Pebbles are you sure ? I guess you know deep down. Take some time but Penny at Serum is fantastic and it's a whole different ball game. If this doesn't work out then Ari, you and me will be out in Greece this summer x

pebbles So sorry if you're right but is it your otd yet, could there still be time? Honey, if it's to be donor eggs, look into epigenetics - you may find it makes you feel a whole lot better about using donor eggs. Your body will turn on (and off) surprising amounts of genetic switches in the baby, so apart from the genetic starting block of the originating egg, the baby when born WILL be 'your' own child.

And I can only second what duggs says - Penny really is fantastic. Remember you can have a consultation phone call with her at any time, you don't need to be ready to cycle there at the time - and she may be able to set your mind at rest on so many things.

Today was otd and completely negative, god it's so depressing!!! Thank you for all your support ladies and Ari thank you for that info I will be googling first chance I get! I hadn't looked into it yet as was still hoping it wouldn't come to that. Mind you the results if donor egg ivf so much higher than own eggs and I just don't know what else to try. There is surrogacy but if it's my eggs that are the problem it's just more waste of money.

Anyway I guess best thing to do is speak to Penny for some advice. Not sure if to keep on taking the hydroxy or not??

Thank god I have you ladies to talk to as think I would go crazy otherwise! Duggs do you fancy another meet up or are you enjoying having a bit of a break from all this?

pebbles sorry to hear about the bfn. I think egg donation would be best for you as it probably is down to the age of your eggs so surrogacy might not work. For the cost of surrogacy you could have a few goes at DE. My friend has 2 DE kids who not only look like her but also have some of her personality traits. How about trying a mix of your own and donor eggs as then you would never know the genetics? If I didn't have DD I would def be looking at DE. You are still the one giving life to the child and you would experience that.

I'm up for a meetup!

Sorry pebbles. I know where u r
Right now.
FET is a sneaky shock as a bfn is just as painful as full on IVF.
I'm up for a meet up. Ari could u join us?
Am currently looking into dates when I can get to Athens....maybe end March and then end of April. Ari fascinating stuff you sent earlier. I am accepting egg donor as most viable
Option you get 3 guaranteed grade 1 blasts for 5k euros. I will take that from a young, proven donor. X

I'd certainly like to if I can, OH's football and DD's recalcitrance to letting me out of her sight for more than half an hour notwithstanding! :)

That's what I do duggs - the 5K proven donor option. Epigenetics is a fascinating subject, and it seems they're discovering more about it every day. I have a vested interest, true, but I find the whole subject really fascinating.

pebbles So sorry about the BFN :( Just a thought, your DH has been tested himself, right? you're sure it's your eggs?

Serum do DNA fragmentation tests on the spot much cheaper than anywhere here ?!

Aw pebbles :(
I've been given neopegen to add to my cocktail!!

They do duggs, yes.

mel Ah, welcome to the neupogen crowd .. and wave bye bye to your bank account. Although of course not as much as for IVIG!

Where's the cheapest place ari? Of course I don't know when or where to have it!!

Mmm That's the $64M question mel. The cheapest place I know of is Asda if you tell them it's for IVF/fertility as they charge cost price on all fertility/IVF meds - last time I heard it was £263 for 5 vials. However, I've never been able to actually buy it through Asda, as their central depot has always been out of stock. Next best I found was Central Homecare @ £303 for 5 vials, then Healthcare at Home which was just a bit more. However, this was as at last September, so prices may have changed a bit. It does seem to be a bit like gold dust (again, I don't know if that has changed), bizarrely!