Thanks Lobster. She has offers, but hasn't firmed yet.
To be honest, I suspect it is just panic. She's been unwell, and we're not even sure she's going to be well enough to go away this year. I'm probably reading more in to her wobble than I should, because I'd rather she was going to be closer to home if she does start.
One of her friends has had a complete change of heart about which course she wants to do, but still wants to go to the same uni. School advice to her is to stick with her offers, and talk directly to the uni about switching course (it is a relatively small change to my mind). Changing uni completely I think means rejecting all offers, and applying one at a time for others (I can't remember if it has a name).
I suppose we have to hope it is a minor wobble, and worry about it when she actually gets her results. Or maybe just see who is in clearing for her subject this year. Last year a couple of good universities were.