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Anti-depressant help

6 replies

jodesxx · 07/10/2026 17:09

I’ve previously been on sertraline and it’s worked wonders for me but I’ve been off it for 6 months and needing to go back on something. Whenever I’ve been on sertraline I’ve lost all interest in being intimate with my husband and haven’t been able to orgasm which has put me of trying it again. The GP suggested mirtazipne this time as I’ve struggled to get off to sleep and been waking up in night. I’m day 3 and I’m just exhausted. I’m so irritable and I can’t function. I don’t think I can sustain this as I am working with two young kids.

I know there are more important things but equally if I can find one that works if I can. I don’t want medication to affect my marriage and intimacy with my husband as that is something we both enjoy.

As we are considering a third child, this limits my options.

The GP mentioned citilopram but is that going to have the same side effects? From reading it will.

OP posts:
EverydayProfessional · 08/10/2026 19:27

jodesxx · 07/10/2026 17:09

I’ve previously been on sertraline and it’s worked wonders for me but I’ve been off it for 6 months and needing to go back on something. Whenever I’ve been on sertraline I’ve lost all interest in being intimate with my husband and haven’t been able to orgasm which has put me of trying it again. The GP suggested mirtazipne this time as I’ve struggled to get off to sleep and been waking up in night. I’m day 3 and I’m just exhausted. I’m so irritable and I can’t function. I don’t think I can sustain this as I am working with two young kids.

I know there are more important things but equally if I can find one that works if I can. I don’t want medication to affect my marriage and intimacy with my husband as that is something we both enjoy.

As we are considering a third child, this limits my options.

The GP mentioned citilopram but is that going to have the same side effects? From reading it will.

All the medication comes with a few side effects so you have to be prepared for that. If you think it is not reliable then ask for other option which could be used alternatively to medicine.

Blarn · 08/10/2026 19:32

I unfortunately found that with all antidepressants. I didn't dislike sex there was just nothing to like or dislike about it, and no orgasm. What I did enjoy about sex though was the feeling of closeness, maybe you could try to reframe it I'm your mind? Unless you don't enjoy it at all, obviously. But it was a really negative side effect for me.

FuzzyYellowCat · 13/10/2026 13:57

You said you were previously on Sertraline and it worked wonders apart from the lack of sex drive that came with it. Could I ask what dose you were on? I have been on all sorts of antidepressants and always come back to Sertraline. I'm on 200mg and have been on that dose for 2 years. Could it be worth maybe being on a lower dose? I wouldn't want you to share if you don't want to but for me personally, I decided to give somatic therapy a go to help deal with past sexual trauma. I have my mental health review in a couple of days and will be asking to lower my Sertaline dose. What aspects are you struggling with which is making you feel like you need to be back on medication? Mirtazapine for me made me very very lethargic and I only lasted 3 days on it.

Yorkshireteaalwayswins · 13/10/2026 14:42

You could try Vortioxetine. It is less likely to have an effect on your libido. It unfortunately didn't work for me and I'm back on sertraline but it has worked for other people.

jodesxx · 13/10/2026 23:07

@FuzzyYellowCative always manged on 50mg/100g so cant go any lower. Im trying some therapy so will see how it goes. Im worse around the time of my cycle as it really impacts my mood. I’ve not gone back to GP yet but I lasted 2 days with the mirtazapine!

OP posts:
jodesxx · 13/10/2026 23:08

Has mirtazapine affected anyone’s cycle? I was due end of last week and I took the mirtazapine at the start of the week but my period is late. I’ve just had spotting on and off for a week

OP posts:
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