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From sertraline to 5-htp?

2 replies

GoldGold · 26/09/2026 17:23

I have been on sertraline for some time on and off but the most recent time I started was 5 weeks ago.

I am concerned about two side effects, increased appetite leading to weight gain and decreased libido. I am on 50 mg.

It has improved my mood and anxiety but because of the side effects I want to come off. Has anyone come off sertraline and found success with 5 htp?

OP posts:
Rockty · 26/09/2026 21:29

No but interested to hear. Saffron also very good but can’t be taken with ssri

Lifejigsaw · 26/09/2026 21:50

No, I looked before I started ssri but there’s no significant clinical evidence of 5-htp working.

it might depend a bit on what the ssri is for. Are you worried about getting the side effects or do you have them/have had them and want rid?

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