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Increasing sertraline dosage 25 - 50mg

9 replies

Belle82 · 22/08/2022 22:11

I was prescribed 50 mg of sertraline recently, I have only been taking 25mg so far to try and ease into them better.

I have been very fortunate with the side effects, they have been extremely mild.

Does anyone have any experience of making this dose increase?

  • If you had no side effects on 25mg - did they start on the 50mg increase?
  • If your first side effects were mild - did they remain mild with the increase?
OP posts:
Luredbyapomegranate · 22/08/2022 22:15

Yes -

My side effects were nearly non existent (a bit of nausea and a dry mouth), and didn't increase with the dose. The nausea was gone in a couple weeks tops, the dry mouth lingered for a bit but was fine.

tithead22 · 22/08/2022 22:23

I was very lucky and didn’t notice side effects on 25, 50 or 100mg.

Belle82 · 23/08/2022 19:48

Thank you so much. I'm looking forward to going up and starting to feel better (if it works for me) I have been a mess for the best part of 20 years when i look back

OP posts:
GetOffTheRoof · 23/08/2022 19:54

The only real side effects for me were heartburn and loss of libido (normal with antidepressants).

The heartburn was solved by taking them earlier in the evening as I had been taking them just as I got into bed, so the lying down was an issue. I also needed at least half a pint of water to wash them down properly.

Belle82 · 23/08/2022 20:55

I experienced the heartburn today when I forgot to drink it with a full glass of water. Wow, I thought what I experienced during pregnancy was bad!

OP posts:
Belle82 · 25/08/2022 19:04

Thank you for your replies.
I am going up to 50mg tomorrow, wish me luck ❤

OP posts:
1981mum1981 · 06/04/2023 12:20

@Belle82 ….., sorry I know this is an older thread but how did you find going from 25mg to 50mg? I took my first 25mg this morning.
thanks

Belle82 · 15/04/2023 12:53

@1981mum1981
it was fine. I did it after 2 weeks if I am remembering correctly. Tired for a while but body got used to it.
I’m on 100mg now.

good luck with it x

OP posts:
Becki31 · 15/05/2025 09:14

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