So iv been suffering with depression for some time now, tried a number of antidepressants from the doctors and ended up on 225mg venlafaxine and 45mg mirtazapine for nearly a year now and still suffering and iv put 3 1/2 stone which has made my even worse the doctor told he he was stuck now has nothing seems to be working for me, so I have now gone through my works private healthcare, I'm having some therapy and have seen a psychiatrist regarding my meds, he has weaned me off the venlafaxine very quickly every 3/4 days had to keep dropping the dose so 3 days ago I stopped them and he's now put me on 30mg duloxetine and told me to drop the mirtazapine to 15mg bloody hell I don't know if I'm coming or going anymore, I also joined SlimmingWorld 2 weeks ago now and have stuck the plan and tonight iv had my weigh in and only lost half a pound and have been so good, I honestly could of cried my eyes out because I'm trying my hardest and don't seem to be getting anywhere just feel like giving up? Is or has anyone else had this?????