Previous poster but have name changed. Just feeling completely low and hopeless. Been suffering with this current episode of severe depression since April although have had reoccurring episodes since I was a teenager. Each episode of depression seems to last longer and longer each time. Have had numerous medication changes over the years, am currently taking mirtazapine at its highest dose and quetiapine at 150mg but seems to be having little or no effect. Not sure what I’m actually posting for, think I just needed and outlet to vent.