I have been taking venlafaxine for just over 3 weeks. I started on 75mg and this was increased last week to 112.5mg last week. I think it has started to work on helping my depression and anxiety but I am experiencing some horrible side effects. The worst of these are complete exhaustion which lasts all day and also my legs feel very shakey. Can anybody tell me if they have experienced anything similar and if so how long did it last? Would really appreciate any advice.