I have suffered with depression off and on for 20 years. Have had under active thyroid for probably about 15 years. The 2 things have similar symptoms. I've recently tried upping my thyroxine dose. I feel so tired and down. I have a wonderful partner but he lives miles away. Not seen him this weekend. We are planning to move in together in the next few months. I feel very alone and miserable. Finding it hard to do anything. I know things will get better but it's tough going through it. Just need my hand holding at the moment.