Hi new to this forum, and its a long story... I had agoraphobia for about 10 years, but got out from all the tablets and have been working for around 30 years. I am now 56, and was being bullied at work for the last six years, and was trying HRT for hot flushes etc. Had my car stolen twice within six months, and house burgled. the doc put me on double the dose of hormones, and gave me the mirena coil.... then everything went black, down a big long tunnel..... This was in November, I was on Seroxat a small dose, for about 10 years, so the doc changed it to Mitazipane 45, not working, so seroquel and a private visit to the pysh. who changed the anti depressant to sertaline, and 50 xr seroquel.... At the moment I am coming off the mitazipane and taking the 50 xr at night, but I am still very nauseaous, and feeling out of it.... Have only been taking the 50 for 4 days.... Any ideas, I jst want to get back to where I was, although anxious, I was able to to work and eat breakfast.....