Husband up and down with mental health problems. Angry for no reason. But now is on a course of Lithium. What a difference! It seems to have given him back a sense of humour, and he's far more easy going. Has anyone else had experience of Lithium. My brother has problems but won't seek help. I m trying to get him to try this. OK, so it won't suit everyone but, for my Brian, what a difference it has made.