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AZ Clots = LATEST From MHRA

90 replies

Emma2021 · 28/04/2021 20:31

Hi

With a lot of talk re clots, and those worried re first jab and possibly many worried re second AZ jabs, the 'Yellow Card' scheme by MHRA
releases details every so often the last lot were on 23 April 2012.

Next lot due tomorrow I think

Read link re first jab clots and 1 for second jab and more and how many people/doses accounted for those clots.

I'm hoping that on the next update possibly tomorrow, there will be great news re second dose of AZ and clots.

I'm also hoping our NHS to udate re treatments, better treatment for these clots.

The link details 23 April re AZ and Pifer side affects & same link will give you access to updates hopefully tomorrow

coronavirus-yellowcard.mhra.gov.uk/

Please feel free to thank me.

PS. There is nothing wrong with wanting honest, accurate, speedy info re vaccines and and side affects as then you can make a more informed decision. FYI i got my second a few days ago was and am worried but on balance of risk as it stands today, I'd get it/vaccine again and I'm over 50 years of age.

Thanks

OP posts:
StarCat2020 · 29/04/2021 07:11

Please feel free to thank me
I am confused.

This link has been posted on MN several times before so it can't be that we are meant to be thanking you for.

PurplePumpkinDream · 29/04/2021 07:53

@Emma2021 Thanks for this link very useful. Off for my second AZ shortly!

beammeupsc0tty · 29/04/2021 08:51

i'm confused @StarCat2020 why you have to be so rude. There is literally no need, if you dont need the link move on and dont comment.

Emma2021 · 29/04/2021 09:58

Thank you

Update. The update is for tomorrow, my apologies for trusting what I read here on another thread. I did my own research and noted the yellow card updates are weekly.

So tomorrow, people waiting for the first and/or second jabs will be more informed re the possibility of clots and a lot more.

I am also hoping for more guidance, better new about what to lookout for re clots, the risk period ie number of days and the NHS having a much better grasp on speedy treatments with excellent outcomes.

Thank you.

OP posts:
Emma2021 · 29/04/2021 10:00

@PurplePumpkinDream
@beammeupsc0tty

Both of you, people like you make my day, many thanks.

Let us all hope that tomorrow brings so really good news re clots and more.

:)

OP posts:
PinkSparklyPussyCat · 29/04/2021 10:16

Thanks for this. I hope there's some good news, I had my first AZ 11 days ago and from a selfish point of view I'm worrying they will stop using it before I can have the second one!

Emma2021 · 29/04/2021 11:46

@PinkSparklyPussyCat

Thanks for this. I hope there's some good news, I had my first AZ 11 days ago and from a selfish point of view I'm worrying they will stop using it before I can have the second one!
Thank you. I will update ASAP but hoping others will update before me. The 'Yellow Card' alerts may bring us very good news re second dose of AZ and even the first. Along with what to look out for over a shorter period I hope and pray.

There will be info on Pifzer as well

Good luck everyone

OP posts:
Rainbowsandstorms · 29/04/2021 12:15

Thank you, I’m also selfishly hoping for good news re second doses and for no great increase in numbers generally either. Fingers crossed for some good news. I’m just waiting for the U.K. yellow card data to be released too as that’s due today.

Emma2021 · 29/04/2021 12:22

@Rainbowsandstorms

Thank you, I’m also selfishly hoping for good news re second doses and for no great increase in numbers generally either. Fingers crossed for some good news. I’m just waiting for the U.K. yellow card data to be released too as that’s due today.
Thank you. I updated my post and its due tomorrow. I should have done my own research earlier.

FYI, the last update was on 23 April 2021 and updated weekly so it will be Friday 30 April as per my earlier post.

Lets pray for good news and those that have had a clot recovery fully and we are soon rid of this hideous virus.

OP posts:
Whichjab · 29/04/2021 12:25

There is not enough people that have had the second jab to be thanking anyone. Only people who had jab before first two weeks in Feb are being called, most of these were in the older age groups.
Also clots can appear within 20 days so many who have had the second jab are still in the at risk period.

Schulte · 29/04/2021 12:56

This is a very bizarre thread if you don’t mind me saying. Firstly, the report does get updated every Thursday, I’ve been following it for several weeks. It can be later in the evening but it is usually on a Thursday. You will also see from clicking on the link that it was last updated on 22 April.

Secondly, of course we are all hoping that there won’t have been any more clots reported after second jabs but the number of clots after first jabs will likely have risen again. So I’m not sure what ‘good news’ you’re hoping for. If the rate stays at 8 in a million, do you count that as good news?

Finally, nice of you OP to post the link and thank you, but it’s true, most people interested in the issue already know where to find the report. There are posters who think we already have too many AZ threads so they won’t be happy to see someone has started yet another one. Smile

Emma2021 · 29/04/2021 15:42

@Whichjab

There is not enough people that have had the second jab to be thanking anyone. Only people who had jab before first two weeks in Feb are being called, most of these were in the older age groups. Also clots can appear within 20 days so many who have had the second jab are still in the at risk period.
Hello Thank you for sharing. As I stated in my OP, one person was indetifieid as clots, sadly there will be more. What I did not see is how many people with second jabs were taken into account and over what cut off period, ie as you said it may take up to twenty days to appear.

However, this time there may be at least a couple of million if not more AZ second jabs taken 20 days before the figures to be released but we shall see and we do need an update

We will also get a better picture on the next 10 million or so first time AZ jabs

The Yellow Card news will also give us details re Pifzer

Whilst I agree with you, IMO we do need the new data to have a more informed view.

I pray that tomorrow brings good news.

Thank you

OP posts:
MiniMaxi · 29/04/2021 15:46

Report’s out for anyone interested

Thanks for the link OP, I for one didn’t know where it was

Emma2021 · 29/04/2021 15:49

@Schulte

This is a very bizarre thread if you don’t mind me saying. Firstly, the report does get updated every Thursday, I’ve been following it for several weeks. It can be later in the evening but it is usually on a Thursday. You will also see from clicking on the link that it was last updated on 22 April.

Secondly, of course we are all hoping that there won’t have been any more clots reported after second jabs but the number of clots after first jabs will likely have risen again. So I’m not sure what ‘good news’ you’re hoping for. If the rate stays at 8 in a million, do you count that as good news?

Finally, nice of you OP to post the link and thank you, but it’s true, most people interested in the issue already know where to find the report. There are posters who think we already have too many AZ threads so they won’t be happy to see someone has started yet another one. Smile

Hello I hope you are well. Thank you for the heads up re Yellow card report updates. I read as "weekly" being 7 days but if its today, great.

Yes, if the rate remains at 8, it will be comforting news as it could easily rise as more people are aware of them now and the good news may be, none were connected to the jabs and with the update we get more news on how to better ID these clots more quickly and new methods of intervention meaning more people will be saved and more will return back to as they were pre-clot/s.

Thank you for your kind words in the last para but FYI, I was not aware of this site and I closely follow or try to follow the stats.
NB: This is not just a "AZ thread" but the yellow card is for the Pifzer and any other vaccines that come into playing. The bottom line, if posters don't like a thread and if they are astute like me, they will jog on.

Appreciated.

OP posts:
Rainbowsandstorms · 29/04/2021 16:34

It’s now been updated for anyone following.

Emma2021 · 29/04/2021 17:09

@Rainbowsandstorms

It’s now been updated for anyone following.
I've been checking but no update
OP posts:
Dementedswan · 29/04/2021 17:10

4 cases after 2nd jab. Out of how many?

Tootsey11 · 29/04/2021 17:12

Another 9 deaths after vaccine, presume after 1st jab. Now 209 cases of clots up from 168 last week. Can't see anything about second doses.

Emma2021 · 29/04/2021 17:14

ok, thanks

second dose up from 1 person to 4, read below

Thrombo-embolic events with concurrent low platelets
Up to 21 April 2021, the MHRA had received Yellow Card reports of 209 cases of major
thromboembolic events (blood clots) with concurrent thrombocytopenia (low platelet counts) in the
UK following vaccination with COVID-19 Vaccine AstraZeneca. These events occurred in 120
women and 89 men aged from 18 to 93 years and the overall case fatality rate was 19% with 41
deaths. Four cases have been reported after a second dose. Cerebral venous sinus thrombosis
was reported in 84 cases (average age 47 years) and 123 had other major thromboembolic events
(average age 55 years) with concurrent thrombocytopenia. Diagnosis was unclear in the remaining
two cases. The estimated number of first doses of COVID-19 Vaccine AstraZeneca administered in
the UK by 21 April was 22 million giving an overall case incidence of 9.3 per million doses. The
data suggest there is a higher incidence reported in the younger adult age groups and
the MHRA advises that this evolving evidence should be taken into account when considering the
use of the vaccine. These reports have also been analysed by the Government’s independent
advisory body, the COVID-19 Vaccines Benefit Risk Expert Working Group, which includes lay
representatives and advice from leading haematologists.

OP posts:
User657849 · 29/04/2021 17:18

Why wouldn’t they just give out more information about this four second dose cases?

They could tell us if it’s following the same pattern in terms of 4-20 days.

Can we assume that if any had died, they would have mentioned it in the report?

Emma2021 · 29/04/2021 17:23

This reply has been deleted

Message withdrawn at poster's request.

Emma2021 · 29/04/2021 17:26

@User657849

Why wouldn’t they just give out more information about this four second dose cases?

They could tell us if it’s following the same pattern in terms of 4-20 days.

Can we assume that if any had died, they would have mentioned it in the report?

Yes, the media questions are controlled and they are often too scared to ask and when some do, they are ignored.

We need to know when people get the warnings.

Sadly, it looks as though the second dose is just as big of a gmable and I await for some to correct me.

They've also not states re the 4 clot cases second does out of how many jabs.

Disappointed a lot

OP posts:
bookworm1632 · 29/04/2021 17:32

So an incidence rate of 9.3 per million, although that will likely climb since the total number vaccinated include all the >60's who are least affected by the clots.

But 19% fatality rate - which will likely fall as we're more aware of the issue now and people and medical staff will be on the look out for symptoms - early treatment is important. Also younger patients likely to be more resilient.

But taking the current data, the fatality rate due to clots would be .19* 8 per million = 1.6 per million.

User657849 · 29/04/2021 17:36

@Emma2021, I think the report mentions 4.4 million second AZ vaccinations.

I would personally also appreciate a statement from the Government saying that since it’s been established that this condition can be diagnosed with a blood test, they guarantee that those with the known symptoms within the known time frame won’t be sent home without the test.

As far as I’m concerned we have a deal: for my age group you only provide this brand, you owe me first class care if something happens.

Emma2021 · 29/04/2021 17:37

@bookworm1632

So an incidence rate of 9.3 per million, although that will likely climb since the total number vaccinated include all the >60's who are least affected by the clots.

But 19% fatality rate - which will likely fall as we're more aware of the issue now and people and medical staff will be on the look out for symptoms - early treatment is important. Also younger patients likely to be more resilient.

But taking the current data, the fatality rate due to clots would be .19* 8 per million = 1.6 per million.

Thank you but just read Reuters and they mention the things i and others have stated ie no data on how many second doses for the 4 people getting clots.

I also want to know when people start getting the warning signs re clots is it at 4 days 7 18 etc we need to know so people are more educated what is the secret?

From reuters

Britain's medicine regulator on Thursday said there had been a further 41 reports of rare blood clots after doses of AstraZeneca's COVID-19 vaccine, but that the benefits of the shot continued to outweigh the risks for the majority of people.

In a weekly update on side effects from COVID-19 vaccines, the Medicines and Healthcare products Regulatory Agency (MHRA) said there were a total of 209 clots with low platelet counts following vaccination with AstraZeneca's shot, compared to a total of 168 reported last week.

There has been scrutiny of the AstraZeneca vaccine on the issue of the very rare clots, with a higher incidence in younger people. Some countries, including Britain, have recommended that only people over a certain age get the shot.

There were 41 deaths following the clots in Britain, the MHRA said, an increase of 9 from last week's figures, although experts say historic cases might still be feeding through to the totals, and the clots are set to remain a rare event. read more

About 22 million first doses of the AstraZeneca vaccine have been administered in Britain. Four cases of rare clotting were reported following a second dose, but the MHRA did not say how many second doses had been given.

Britain has advised that under-30s receive an alternative to the AstraZeneca-Oxford vaccine, after the MHRA medicine regulator found there was evidence of a link to rare clots with low platelet levels, and officials are considering whether to change advice for people under 40 too. read more

Officials have emphasised the side effect is "vanishingly" rare and advised that most people still get the shots, and AstraZeneca has pointed to regulator recommendations that the vaccine is safe and effective.
www.reuters.com/business/healthcare-pharmaceuticals/british-regulator-cites-41-more-blood-clot-reports-following-astrazeneca-shots-2021-04-29/

OP posts: