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Oxford vaccine approved!

218 replies

Rosehip10 · 30/12/2020 07:01

Good news

news.sky.com/story/covid-19-oxford-astrazeneca-vaccine-approved-for-use-in-uk-12155958

OP posts:
ineedaholidaynow · 30/12/2020 11:17

Briefings are better when politicians aren’t involved

Notthemessiah · 30/12/2020 11:21

[quote sonicbook]@Notthemessiah and nobody is bandying about 90 percent -every report I have seen has emphasised the 60

@PurplePansy05 because they just don't know about it and will, understandably, be looking to cover their back in terms of litigation. I'm with you, I'd probably have it pregnant or not. [/quote]
I wouldn't say they have emphasised it. The graphic on the main BBC article still has 62%-90% as its effectiveness and mentions the 90% figure twice, even though we know now that this shouldn't even be being included any more.

Also the Daily Mail mentions both figures but does not seem to state that this approval is only for the two full dose regime (unless I've missed it - don't like to linger too long on the Mail website).

I get the desire to be trumpeting the good news (and it is definitely good news), but we still need to look critically at everything the government says, especially over something as important as this.

PuzzledObserver · 30/12/2020 11:30

@PurplePansy05 - if what you disagree with is pregnant/ttc women not being allowed to choose for themselves, then your wish is granted.

Good luck.

Spiratedaway · 30/12/2020 11:45

@Dongdingdong

You can all say what you like about the UK’s handling of this, but as a nation we’ve done bloody well to get 100 million doses of this vaccine on order. The Washington Post said we’ve been leading the pack as a country.

The only people who won’t like this news are those MN posters who have appeared to relish in scaremongering and spreading doom and gloom throughout the pandemic. With a vaccine being rolled out and the Brexit deal done, what will they have to moan and scaremonger about now?

Well said
PuzzledObserver · 30/12/2020 11:51

@Notthemessiah

As I said, I think this is definitely good news and certainly better to have this vaccine than nothing at all, but I am concerned about the mixed messages regarding it's efficiency and the changes in doses and timings and the fact that these seem to have been discovered more by accident than design.

My prediction is that at least 90% of those who said they were probably or definitely going to have the vaccine when asked will not care a stuff about the figures. When they are invited, they will go, and won't spend hours quizzing the administrator as to whether it is 62, 70, or some other number effective. They will be glad to have finally got it.

And if they are told that the second dose is needed to make protection "long-lasting", which was what was being said at the press conference, they will present themselves for the second dose as well, whether that is 4, 8 or 12 weeks later.

Abraxan · 30/12/2020 12:01

@CeeJay81

Am I the only one that can't get excited excited about a vaccine that could only be 62% effective. The vulnerable should have the Pfizer one at least.
I find the news great. I'm group 6 and work in a school. I've had covid but as there's no way of knowing if I can get it again - and the complications covid has left me with another issue which increases my vulnerability to it - I'm eager to be vaccinated as soon as possible.

Re the effectiveness, the flu vaccination effectiveness varies each year., for example.

Oxford vaccine approved!
LouiseBelchersBunnyEars · 31/12/2020 03:29

The fact that these results, like the half dose thing, seem to have been discovered by accident rather than design does not exactly inspire confidence

Lots of great things in science have been discovered entirely by accident.

Penicillin for one off the top of my head.

I don’t think you can read too much into ‘accident rather than design’ beyond being thankful the ‘accident’ occurred 🤷‍♀️

NeurotreeWenceslas · 31/12/2020 07:30

Oh gosh yes, half of science is accidental and from observed results rather than planned!

BernadetteRostankowskiWolowitz · 31/12/2020 07:37

62% is better than 0%. If the only contraceptive available was 62% effective would you never have sex again? Or would you use it and think "better than nothing"

There are still steps we can take to minimise our risk of catching it (avoiding those with symptoms/ hand washing/masks etc)

Nc135 · 31/12/2020 08:27

This vaccine is at least 60% effective at no symptoms at all and 100% effective at keeping people from developing severe disease/needing hospitalisation. What is not to like?

This is a bloody miracle. We now need to stop moaning and get as many people protected as quickly as possible. And how bloody lucky we are to live in the U.K. with now two vaccines approved.

Nc135 · 31/12/2020 08:30

Read this from the head of the research. I posted it upstream but so important people don’t speculate and read it from the scientists themselves. This is a game changer.

Prof Sarah Gilbert of Oxford University’s Jenner Institute, who led the research, told the Guardian that people in both dose groups were protected in the trials from severe illness after just one jab.

“I have no qualms about using the high dose/high dose regimen, which is what the majority of people in the trial have had,” she said.

“It’s really important to note that within 21 days of the first vaccination, nobody was admitted to hospital with Covid or had severe Covid and that’s just after one dose – that’s after any one dose in these trials – no admissions to hospital, and that’s a really major result for public health benefits.”

Both the Pfizer/BioNTech and the Moderna vaccines have reported 95% efficacy in their trials, but Gilbert said it was important to see how well the vaccines did after six months or a year. “It’s great to see high level of efficacy but that’s not the final answer on any of the vaccines really because it’s something that we need to accumulate data on over time,” she said.

There is no evidence yet on the durability of protection from the other two vaccines, both made with novel mRNA technology, whereas Oxford used an adenovirus vector – a technology that has been shown to provoke a long-term response, she said. “We shouldn’t get too hung up on comparing these early numbers.”

Nc135 · 31/12/2020 08:32

@BernadetteRostankowskiWolowitz Yes and this vaccine is even better than that. It 100% stops hospitalisations.

Nc135 · 31/12/2020 08:34

It doesn’t matter if you have the half dose/full dose regime. Or the full dose/full dose regime. The point is that ONE jab 100% stops hospitalisations. Whether that is a half dose or a full dose. Read the head of research.

MarshaBradyo · 31/12/2020 08:35

@Nc135

This vaccine is at least 60% effective at no symptoms at all and 100% effective at keeping people from developing severe disease/needing hospitalisation. What is not to like?

This is a bloody miracle. We now need to stop moaning and get as many people protected as quickly as possible. And how bloody lucky we are to live in the U.K. with now two vaccines approved.

Yep well put
Truelymadlydeeplysomeonesmum · 31/12/2020 09:32

Notthemessiah

Have you ever heard of penicillin?

Some of the greatest scientific discoveries in history have been found by accident whilst experimenting for something else.

Truelymadlydeeplysomeonesmum · 31/12/2020 09:36

@Nc135

This vaccine is at least 60% effective at no symptoms at all and 100% effective at keeping people from developing severe disease/needing hospitalisation. What is not to like?

This is a bloody miracle. We now need to stop moaning and get as many people protected as quickly as possible. And how bloody lucky we are to live in the U.K. with now two vaccines approved.

Yep
Nc135 · 31/12/2020 10:10

The other miracle with this new Oxford vaccine is that the majority of protection happens after only one dose. That means - no severe disease or hospitalisation after one dose. Whereas we know that the Pfizer vaccine needs both doses for the max protection. Within 3 weeks.

Again both vaccines a bloody miracle but I am wanting my parents to get the Oxford vaccine because that will give the highest level of protection as quickly as possible.

That was from an interview with a scientist from Imperial this morning.

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