Oxford initial news

[tobee]

Covid-19: Oxford University vaccine shows 70% protection www.bbc.co.uk/news/health-55040635

Re. Tanking in the markets and U.S licence, I wonder if there is a bit of irritation with the Oxford vaccine that this is a vaccine that is cheaper and logistically easier for the rest of the world to buy and may therefore affect moderna/ Pfizer sales?
Remember Pfizer tried to buy Astra Zeneca a few years ago but were blocked by the U.K. gov, so maybe a bit of politics coming into play?

I reckon so, why has one analyst been given so much airtime with what sounds like flippant comments.

Cheaper, easier, results look good

It’s probably a bit like trying to sell your expensive house and then your neighbour puts theirs on the market the next day for £50k cheaper and they don’t have a chain
You would be a bit cross!

It's a bit concerning that the US are saying that about the Oxford vaccine. It'll fuel the antivax people in other countries. There is a huge amount at stake financially here too so hard to separate science, financially motivated statements and people's innate tendancy to trust their own government more than others (Anyone for the Sputnik vaccine?)

@ForBlueSkies exactly spot on with your analysis. Unfortunately a poor loser to the mRNA vaccines. If the chimp adenovirus is the “issue” it’s a one trick pony too as won’t be repeatable if required say for annual boosters. Personally think U.K. need to buy up more of the better performing vaccines.

The U.K. is also developing an mRNA vaccine at imperial college that is in phase 2 I think. So if MRNA are the future of vaccines then we have something in development but at least the Oxford vaccine will get us through the next 12 months or so.

@sashagabadon that’s good 👍. I’m just a sore loser.

[quote ForBlueSkies]AstraZeneca are tanking in the markets today as there is speculation the vaccine will not be licensed in the US:

SVB Leerink analyst Geoffrey Porges said the treatment may never gain approval from US regulator the FDA, and said Astra had highlighted results from a “relatively small” number of patients

Adam Feuerstein
@adamfeuerstein
SVB Leerink analyst Geoff Porges sharply critical of $AZN #Covid19 vaccine, calls announced efficacy results “embellished” and raises questions about safety data disclosures.

Porges predicts the vaccine will never be licensed in U.S

The combination of lower effectiveness, a troubled trial design and the occurrence of severe safety events make Porges believe the product has no future in the U.S. The analyst also said Astra and Oxford officials would be “roundly criticized” for their lacking safety disclosure that was “hardly reassuring.”

www.telegraph.co.uk/business/2020/11/23/markets-live-latest-coronavirus-news-pound-euro-ftse-100/[/quote]
Looks like other people think it is also a bit shit as well then.

Obviously it’s ok for the here and now, better than nothing etc. etc.

But everything we do in the uk now, despite us constantly bleating about ‘world beating’ stuff is just a little bit shitter than what other countries can do.

We were first into trials, third to come out of them. Smaller sample sizes than the others, 70% ish effective (no one knows about the 90% yet and how long will it now take them to test the 90% dose as they used such a small test group size the first time and what dose will people get in the meantime) and a vaccine that can probably only be used once.

We’re world beating alright

[quote Oaktree55]@sashagabadon that’s good 👍. I’m just a sore loser.[/quote]
We’re not a loser though. We’ve produced a cheap, easily transported, effective vaccine in less than 10 months that the world will benefit from in 2021 at least even if it becomes less useful over time. We should be pleased and proud of the achievement.

The narrative has moved to it’s cheap and easy to transport 🤣. As we Brits love to say it’s the taking part that’s important!

@sashagabadon yes but the Germans and Americans have done better. The Ebola vaccine was apparently required to be stored at same low temp and it was achieved. It’s a shame the figures aren’t better that’s all.

Honestly Covid fears you were being negative like this on another thread too. It makes me suspicious of your motives?

The other two may well aid the developed world but there is no way that other countries will - its delivery and storage system is just too complicated and it is very expensive.

The US may not use it because why would they when they can charge for the far more expensive one

India for example will get the Oxford Vaccine - it produces it and will buy an awful lot of it. It will play it part

@Oaktree55

The narrative has moved to it’s cheap and easy to transport 🤣. As we Brits love to say it’s the taking part that’s important!

What 'narrative'?

Not much point having a highly effective vaccine if you can't afford it or the logistics make it very difficult to administer, as would be the case in much of the world for the Pfizer vaccine, but not the Oxford vaccine.

@Oaktree55

The narrative has moved to it’s cheap and easy to transport 🤣. As we Brits love to say it’s the taking part that’s important!

exactly! All the decent countries will be having the 90% effective ones and us (and the third world) will be stuck with the second rate one no doubt, because it’s cheaper.

@Oaktree55

The narrative has moved to it’s cheap and easy to transport 🤣. As we Brits love to say it’s the taking part that’s important!

But that is hugely important for many many countries Oh well carry on your negativity if you prefer, meanwhile I am delighted with the news

Eh? We’ve bought loads of the other two too. I think your just trolling now

@sashagabadon

Honestly Covid fears you were being negative like this on another thread too. It makes me suspicious of your motives?

No motive at all. Just sick to death of hearing people singing the often undeserved praises of what our country has to ‘offer’.

Yes, it likely has its place for one vaccination. Then what? All the millions that have gone into that vaccine.

the Germans and Americans have done better

Slightly pathetic to see this as some sort of contest, but if you insist on so doing, and even if we fully accpt your 'narrative,' then coming 3rd out of the 200+ nations on earth hardly makes Britain a 'loser'.

@Covidfears

Yes, it likely has its place for one vaccination. Then what? All the millions that have gone into that vaccine.

Sigh

It has always been known that it would need a mixture of vaccines to work - the oxford vaccine has done exactly what it set out to do. Be a stop gap of reducing it

And as a previous poster said even in the cases that had COVID it was a mild form.

We are likely to be able to get ourselves back to normal using the oxford vaccine quicker than using others - I dont get the downside.

I’m very pro Oxford vaccine success. But I missed the part about why only once?

Anyway, I’m leaving this thread now so you can get back to your backslapping and fist bumping

@MarshaBradyo

I’m very pro Oxford vaccine success. But I missed the part about why only once?

It may have to be jigged around with each year like flu vaccines. The mRNA vaccines may be longer lasting. That is how I understand it but happy to be corrected