Uk hospital now saying covid patients don’t seem as sick as they did at beginning of epidemic

[Blueberryham]

Just saw on yahoo news

All respiratory viruses lose their virulence in summer months.

Unless you live in Arizona, I guess.

Being serious, folk in AZ live indoors in summer. Their summer is like a cold country's winter for living indoors as much as possible.

Bubonic plague is actually still hanging around, mainly in DRC, Madagascar and Peru!
www.who.int/news-room/fact-sheets/detail/plague

Florida dashboard is way way cool. Another place in summer right now. And the further south you go, the more cases, seems like.

Coronaviruses are actually much more likely to mutate than chickenpox, a member of the herpes virus family. Herpes viruses have DNA genomes, whereas coronaviruses have RNA genomes. When RNA replicates it lacks the error checking mechanism that DNA replication has; hence more mistakes are made and mutation happens more regularly.

I've seen various reports on MSM but not sure if any have been peer reviewed yet.

The 2 theories seem to be

Less viral load. Which could be due to SD and quieter places and mostly outdoors.

A virus needs a host to breed. Therefore if it's too lethal (and again with SD) it needs to be less fatal so host can transmit it.

But I also think we do still have the strain of Spanish flu around? So I guess some do die out with regards high transmission wise but are still around?

The plague killed millions. But I think that in 2020 we shouldn't have any such killer virus with all the money that goes in to medical research.. We are also much cleaner than the middle ages.

Coronaviruses are actually much more likely to mutate than chickenpox, a member of the herpes virus family. Herpes viruses have DNA genomes, whereas coronaviruses have RNA genomes. When RNA replicates it lacks the error checking mechanism that DNA replication has; hence more mistakes are made and mutation happens more regularly.

This is normally true with RNA vs DNA viruses (no second strain to compare against) but is actually NOT true with coronaviruses. They have a unique error checking process/molecule involved in viral replication so they actually have an unexpectedly slow background mutation rate compared to RNA viruess and many DNA viruses - which is a good thing for vaccine and antiviral treatment development.

@GuiltyBark

I imagine it's helped that they are admitting more moderate cases now for the oxygen like Boris had. In early days you'd have to be more poorly, blue lips and gasping and at that point it was likely to be a poor prognosis anyway.

It took a few weeks to clock that moderate cases were dropping off a cliff with no notice, if memory serves as you could go from being unwell to suddenly in crisis, but as criteria for admission was so high people ended up dying at home. Once they allowed more people in to hospitals at an earlier stage on they could pull more people through.

Think you have it here

There's little context so it's fairly meaningless.

There were 160 plus minutely different genotype incursions of corona, so we might be lucky the severe dying out the mild staying, need gene experts to test that. More likely all of the things mentioned before in this thread are relevant summer, better care, quicker more accurate assessment etc. etc. But make no mistake it is shaping up for a second very patchy wave. Viewed from animal science point , Vit D important and Vit E and Vit A are also highly relevant but use correct dose rate. Vitamin C not to be discounted. The much published Dexa story is in fact old but now confirmed by RCT. The real problem is that in the last H1N1 major flu outbreak very very little high quality research particularly RCT was done on the main NSAIDs. Right now there is scramble to check them out. Very likely they have a major role but have to be used for right patient at right time. Used incorrectly (just like steroids) can make things worse. NSAIDs and steroids are used (judiciously) in animals a lot with certain respiratory conditions . Time and place is everything.
Not looking forward to winter unless we have some major research break throughs.

I imagine it's helped that they are admitting more moderate cases now for the oxygen like Boris had. In early days you'd have to be more poorly, blue lips and gasping and at that point it was likely to be a poor prognosis anyway.

It took a few weeks to clock that moderate cases were dropping off a cliff with no notice, if memory serves as you could go from being unwell to suddenly in crisis, but as criteria for admission was so high people ended up dying at home. Once they allowed more people in to hospitals at an earlier stage on they could pull more people through.

From my understanding this is why Germany's death rate is so low. They had corona taxis and treated people with oxygen at home from early on in their illness.

That's helpful @NewNewt