RESPONSE Trial for recurrent miscarriage: Thread#3

[Marchgirl]

For anyone on the RESPONSE medical trial for recurrent miscarriage, or thinking of joining. Peeps at all stages of the trial welcome!

Link to previous thread is here

I didn't have Any swabs etc done after 32 weeks so I have no idea how mine was picked up then x

Wow it's a scary thing then!! Thanks for clueing me up on it! I might mention it to my midwife too..
Ah a sonicade, the same as a Doppler yeah?
I've not been sleeping well lately but yday our new bed and mattress came and I slept like a baby!! So much love for the bed right now lol :)
Any luck testing this morning girls?
I'm off to the wedding dress shop today with my mam to collect my dress and buy the underskirt and veil - eeeeek! Enjoy your wkends :) xx

Yes Doppler, sorry ha ha!

No clue Claire, maybe yours was quite strong in your system early on?

And yey for better sleep and wedding dress!!!!!! Enjoy it!!

choccy - if it detected at any point it has to be treated during Labour so doesn't really matter I guess.

ooh enjoy philippa x

Ooohhh Enjoy dress shopping Phillipa

Bfn for me again

sorry about bfn kazz how many dpo are you again?x

Another bfn for me too :( af due in 2 days ????

13. Af due Monday. same as Genwah.

Trying not to be down. I'm away with my mate this weekend who is in the 2ww waiting to find out of her 2nd attempt at surrogacy has been successful and expecting a hysterectomy I'm the next 6 months at 32. She's literally the most amazingly lovely person you could ever meet. Puts our difficulties into perspective. I would do anything for her to get good news next saturday when they test.

Sorry for the bfns. Totally gutted for you both. Really hoping next month will be luckier x

Bfn again this morning and I can feel AF is en route so we're definitely out this month

Bfn again this morning and I can feel AF is en route so we're definitely out this month

Hope your okay kazz xx

Bfn again this morning and I can feel AF is en route so we're definitely out this month

Oh my God. how many times has this posted?! I'm ok. Had a great weekend with amazing friends and been reminded we're still very lucky because my friends situation is so much worse. Good luck to you and March now for the next bfps.

Sorry kazz. This process is shitty.

Hi ladies sorry I've not posted for a few days, been super busy!
I had my randomization appointment on fri, all went well & didn't take as long as I was expecting...was out in 3hours. I'm not finding the injections anywhere as near as bad as I was expecting! I've noticed I feel crampy since starting the injections, not really menstrual cramps just achey feeling across my lower stomach & occasionally in lower back...have any other ladies had this? Apart from this I'm feeling ok & trying to stay positive

Sorry to hear you got another bfn this morning kaz...I really hope next month will be your lucky month! X

AF has started to arrive. A day earlier than expected and it's bloody horrible. I'm in so much pain! just home after a 5 hour drive from south Wales and I'm exhausted! I think a takeaway may be on the cards because I just can't be bothered cooking!

brummie I had exactly the symptoms you described and also got throbby feelings in my boobs about 15 mins after injections too. I think knthese lasted for pretty much the full 12 weeks.
Sorry AF has arrived kazz. Get stuck into that takeaway!

Take away ordered and DH is searching out some pain relief for me!

Feeling a bit panicky atm after learning about the October deadline. based on that we have 3 more shots. but... if my cycles stay 4 weeks our middle remaining cycle will fall when were on holiday and I think I'd be a day too late to be randomised when back? (am i right you have to syart injections by 5weeks?) and cycle 3 could overshoot the deadline. so we may only have one guaranteed cycle

trying not to think about it though because it's out of my control!

I was thinking how awful that October deadline must be to deal with. It seems pretty brutal to be honest.
Hopefully you'll be automatically enrolled in the next phase of the trial which may start shortly after October? Time wise I presume that the latest the next phase would start is jan 2016, to allow those who conceive in October to reach the 12 weeks and have the full drug / placebo course.
Hoping you get some clarity from your trial team so you don't feel too much pressure.

The next phase of the trial? what do you mean?

How are you getting on Size? Are you past 20 weeks now. I lose track of everyone!

I wouldn't rule yourself out of the middle cycle kazz. If it's only a day you could just lie! Or maybe you could be randomised before you go away if you get the bfp early enough? Anyway, that's irrelevant because it's coming next month!!!

What have you heard about phase 2 size?

Kazz you're meant to start injections within 3 days of your bfp, so whether you get that at 3,4,5 or 6 weeks it doesn't matter so I was told anyway.

So sorry ad has arrived and hope you enjoyed your takeaway!!

Oh Kazz, that's pants. Get stuck in to the take away, I'm having a pot noodle!!!

Brummie, I had cramping across the top if my tummy after injections. Lasted a couple weeks maybe. I think Phillipa might say similar if I recall correctly.

As for the trial ending etc. I haven't heard about the October cut off. But my last chat with the nurse, she said they have found its taking a lot longer to get the BFPs than originally thought, they have over 50% of the original 150 needed. So I think they could go on for a while waiting to get 150 BFPs, so they are stopping soon so they can process the findings. Don't quote me on it though.