RESPONSE Trial for recurrent miscarriage: Thread#3

[Marchgirl]

For anyone on the RESPONSE medical trial for recurrent miscarriage, or thinking of joining. Peeps at all stages of the trial welcome!

Link to previous thread is here

Sorry it's a bfn kazz, but you're still quite early aren't you? It's not over til the fat lady sings

I got my smiley a week last Sunday? so 11dpo? is that right? So yeah - still possible

Kaz2112 congratulations on the new job!! Fab news! Sorry you got a bfn this morning, you're still early so hopefully you'll get your bfp in next few days.

I didn't contact hosp yesterday as I retested in afternoon & it was still so faint so thought I'd wait till this morning to check & I'm pleased to say the line is still there & slightly darker! Will ring hosp at 9 to see what they say.
Not so good news is that my little boy who is 3 has woken up covered in chicken pox!! I know I definitely had it as a child so I'm hoping that means I'm immune.

genwah85 I was given 3 months supply of ovulation tests & I was given 12 pregnancy tests...I did think 12 wouldn't be enough for 3months if they're expecting you to test from 7dpo.

I got 3 packs of ovulation tests and 20 pregnancy tests so that's definitely not enough Genwah. any news from you?

Congrats on the job kazz!! And super congrats to you brummie!! Let us know what the hospital says :)

I've got an appt today to get my last batch of injections! Scary to think I'll not be having them :s
Saw the midwife for my booking appt yday and was given a pack etc, it's kind of made it seem more real!
Oh laughs at me... If I have cramp or random pains, I'm worried. If I don't have cramp or random pains, I'm worried! Honestly I just wish I could chill about it. Anyone else like that? X

Ffs kazz :( still not over!!

Brummie!! Yippee!! Hope you got an appt ok!! Re chicken pox, my ds got it when I was just over 7 weeks, I was told all ok as long as I'd had it already. Also told you can't catch shingles from chicken pox so that's good news :) Hope he doesn't suffer too much, thankfully my ds got away with only a few spots and back himself within a few days.

Philippa, yey on your last pack!!! Totally get you on the pain/lack of!!

Just had an email from my Response Research nurse. The trial research company have set a date of the 1st October to stop randomising.

No pressure then!

so if not pregnant by then you will come off trial kazz?x

Basically yeah. No one new will be randomised after 1st October. If I'm not pregnant now it gives me 3 more attempts assuming my cycles stay exactly 4 weeks!

same here kazz x

Hoping you ladies get your bfp before trial ends! There's still hope for this month.

I rang hospital today & I've been asked to go in tomorrow morning for to collect my first batch of medication...does anyone know what first appointment entails & how long I should expect to be there? I'm so nervous about the injections, I'm not good with needles & my husband is even worse lol I know how much I want this to work so I know I'll have to bite the bullet & do it, should be used to it after a few days...I'm hoping!!

No pressure at all! Fingers crossed you're all pregnant before then :)

Brummie it's all quite long winded! They take plenty of blood, I think about 8-10 vials? They do basic stats so height, weight, blood pressure etc, then ask you when you got your smiley. Your details are put into a computer and you get 'randomised', the long waiting is mainly for the pharmacy to do the prescription! Normally mine take about 2 hours! :/ You are then shown how to do the needles and diary, I get my oh to do mine as I don't have the bottle!! Then after your first injection you have to wait and hour to make sure there are no side effects, I think they redo your blood pressure etc then too maybe. Once all that's done off you go! It's easier than you think honest :) xx

Oh and we were there for 5 hours in total! X

Another bfn for me this morning :( I haven't had an email? I might give them a call as would like to know how long I've got, Eugh the last 2 times we tried we caught straight away, typical it wouldn't happen the month we tried!

Brummie, as Phillipa said. I was there about 4 hours.
Details, vital statistics, randomised, waiting for syringes, get syringes, shown and DO the first one, wait an hour, and then vital stats again.
Then off you go with your syringes.

Depending on the time you take your first injection, you can gradually move the time by four hours either way.
So my injection was midday, and I was racing home at lunch to do it. So I moved it to four o clock.
As long as your within 20-28 hours of the last injection.

Keeping everything crossed for all you ladies, hoping and praying it happens for your all soon xx

Brummie I got there at 8.45 and left at 2.30! It's not a quick process.
I used to do my injections at about 11am but I'm home all the time so it's easy, had I worked I'd have done it in the evening as if I did it in the morning and forgot I'd be screwed as I'd be out all day.

I was told about the October thing today too as I spoke to research mw, exact words I used about the no pressure then! I just thought it was new people signed up in June that only had til then, not everyone :(

I'm the same Genwah. Got caught within 2 cycles every time we tried last year. 7 months since last mc and despite not actively avoiding it for the first few months and very actively trying now for 3 cycles we've had no luck. So disheartened!

Looks like another bfn for me. Now going to get in the shower and have a good cry. I feel so frustrated! I just don't know what else we can do!

sorry kazz I know exactly how your feeling. 7 months since my last mc and we 've tried ever since with no luck. big hugs its so tough xx

I just don't know what we can do differently. The only difference between now and the first three times i fell pregnant is that I've put on weight bit were talking about 10lb. Not stones and stones. I'm 12dpo one and just feel.like that's it for this cycle. another down the drain

I feel same Kazz I really expected too just catch again, and I'm so frustrated only thing I can think of is that this is my first cycle since last miscarriage and maybe that had something to do with it, my af it's due in 3 days so just need to suck it up I suppose :( xx

Oh kaz, there's not much more you can do but believe it will happen. I know how much it sucks to hear all those cliches, but they are true, matters have been made worse due to the whole 1st October thing :/

Strangely for me, every 4th cycle we fell - BUT my weight fluctuated loads during that time and it never affected conception. My bmi's 35 now so I'm pretty overweight - reassuringly though, it never seems to have affected our fertility. Try not to get hung up on possible factors, remind yourself you and your do are doing all you can. Hugs x

Kazz I'm so sorry, it's so frustrating :(
Not saying it is the problem, but when I fell with this one, I'd just spent theonth before doing Jillian Michaels 30 days shred and eating super healthy. I lost my xmas and holiday weight (12lbs) and felt so much better in myself. We'd just had 3 months off trying too so I was ready to get at it. I think it just boosted me in the right direction and made me more confident trying again. Again, not saying that's the problem, but if you feel good in yourself I believe it helps massively xx

Ps af isn't here yet ;)