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Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

Original poster

Immune /natural killer cell treatment when ttc or pregnant (aka the 16th pred thread!)

992 replies

sunnyday01 · 05/06/2015 19:22

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

OP posts:
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5
Snoopysimaginaryfriend · 13/06/2015 21:33

Sorry trying just saw your post. It more than likely wouldn't come to that anyway. You've got loads of options and like you're doctor said this time you only needed ten Smile

Excuse my ignorance but when I read your posts I always think 'SO' means 'super ovulation'. I know that's probably wrong so what does it stand for?

Snoopysimaginaryfriend · 13/06/2015 21:34

Oh and he did ring this Friday gone so as you can imagine I was a bit depressed and I just thought 'f* you!'

Samwaygangeee · 13/06/2015 21:39

Just peeping in with a happy story - I had very raised NKs, my progesterone was all wrong and a history of autoimmune disease.
I had ICSI at ARGC plus dex, clexane, progesterone suppositories AND bum injections, and aspirin. First cycle my HCG was v v v low but they upped the dex and IIt suddenly rocketed. The result of this has this afternoon drawn on his bedroom wall in laundry marker!
Second cycle they tweaked everything so started the dex sooner, two clexane a day not one big one, more prog, aspirin etc and both embryos implanted this time and I had twins, who have been little pests today too.

It can all seem so overwhelming and unfair but once it's over its like it never happened. Very best wishes and good luck to you all x x x

Tryingno1 · 13/06/2015 21:42

Yep it's super ovulation! Hula is about to start! Yay! Rosa got preg on it so hopefully more good news from it soon.

Im stressing about my weight too. I got my bmi to 24.8 pre ivf, it always hovers around 25. But last 3 weeks I haven't counted calories but I'm eating really healthy (7 of my 5 a day, lots of chicken and organic milk, nuts) (ok I am having one sweet thing a day like icecream or a Choc! But only a small one) but I know I've put on weight coz my trousers were tight tonight....I know I shouldn't worry but I just hope it doesn't add too much to miscariage risk . Also I refuse to weigh myself as I'm scared to see the result and I don't want to stress out and starve muself! My ivf doctor said during ivf it was imp not to be calorie deficient and it could be counter productive.
I think I've become a stress head!

Seekingmiracles · 13/06/2015 21:57

Thank you for your happy story Samway! That's amazing!!

My fish was 8.5!! Haven't had it retested so not sure if acu has helped. Not sure I really want to know. I just know I don't want it getting any higher.
I really don't want to wait to try again. I'm one of those who has to just get on with things. I feel like waiting would just be a waste of valuable months but I'll see what he says when I see him.
I also really don't want to know if the baby was a boy or a girl. It would break my heart further thinking of what could have been.

Why does SO seem to take a few cycles to work?? I've mentioned it to dh if we're not lucky by Christmas.

Tryingno1 · 13/06/2015 22:10

I know don't know the literature around So is mixed. Sunny took 5 months on it and then got preg without trying 2 months down the road! It's so bizzare. But rosa had sucess wuickly after a while of trying so maybe it's right for some
People

Samway thanks so much for ur story!!! I'm on Isci and on the same combo as u were! It's exhausting taking all the meds and I feel shit! But it's just given me an extra boost knowing this might work. Congrats on ur two kids how wonderful xxx

Tryingno1 · 13/06/2015 22:13

Actually I'm not on the bum rogesterone. But I may ask for my
Levels to be monitored if my consultant lets me. But I am
On tds rather than bd so maybe that's enough.

Snoopysimaginaryfriend · 13/06/2015 22:15

Thank you samway, it's always good to hear success stories, especially twins! And you're right, when we all get there we will eventually forget how much this journey hurts.

seeking when I saw Dr s earlier this month after my third he said to at least wait until Af arrives to give you a little time to recover. DH wanted to get straight back to TTC but he is adamant that wee follow doctors orders to the letter this time so we are waiting. I too really want to be pregnant again but If I'm honest I havent missed all the anxiety that now comes with TTC and bfps. Oh when I think back to when we first tried, first few weeks off of the pill success straight away, it almost makes me cry

Snoopysimaginaryfriend · 13/06/2015 22:18

Oh and trying I'd imagine that all of the meds play havoc with your metabolism so don't worry. I'm starting to develop a little belly from comfort eating and if the newspapers are to be believed I batter shape up fast or I'll probably be sacked Grin

Tryingno1 · 13/06/2015 22:19

I know snoopy me too. I got preg first month of trying (tWice) now I've ended up needing isci?! Wot the fuck!? I know I've repeated this so many times but I still
Find it shocking. Sorry for the use of the swear word but it was required! It goes to show u don't know wots around the corner and life can change and be so unexpected. Hopefully we will get there and we will forget it all....hope stories keep me going
Night girls x

Tryingno1 · 13/06/2015 22:21

Yeah I know snoopy. I've been so tired I haven't been able to excercise and I do comfort eat. But I haven't touched alcohol or coffee or coke for 3-6 months and I eat very healthy(minus the odd cake!)

Original poster
sunnyday01 · 14/06/2015 08:10

Morning Arrived late last night in Turkey, woke up this morning to briwn blood when I wiped - can't believe it. Trying not to think the worst but I am so scared.

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Seekingmiracles · 14/06/2015 08:33

Oh Sunny.... I'm so sorry you're on holiday and now you have this worry. I know my journey hasn't ended well but DrS really wasn't too worried about my brown discharge and I genuinely don't think it was an indicator of things to come. Try to take it easy and if you have any further concern try to see a DR over there. I will keep everything crossed that its just a bit of old blood working its way out. I know for us, with our history anything out of the usual is absolutely terrifying!

Trying how are the embies doing?? Hope all are maturing well!!

Tryingno1 · 14/06/2015 08:39

Oh sunny! Don't worry. Obv that's impossible. Just think postive. Ur on the meds and u had a great scan. Brown is common and ur on asprin.
Lie in the shaded sun, read a magazine and drink lots of water and think postive. Big hug. I think rosa had brown too early on...this journey of TtC and miscarriage is so hard for us isn't it. Ugh. One worry after another.

Seeking no call yet! They said it would be later today so as usual I'm feeling nervous! Although my regurge bloating and generally feeling shit is better! Ithink it was a mixture of nerves and post egg revival. I felt shocking yest! Going to watch what I eat now I'm over the worst or otherwise I'm going to become a whale!

How r u? Did u sleep ok? When is ur d and c again? Re the gender u could tell mr s u don't want to know, that's wot I was going to do but never got results. Only problem if its a girl it could be ur DNa they tested and u can't be 100percent sure. But I agree knowing the gender would break my heart more :( but for some maybe they prefer it I don't know.

Seekingmiracles · 14/06/2015 09:27

I feel like a whale too...8 weeks of no exercise and being a little less controlled on the diet front has left me feeling fat and gross. Going to write myself a little get fit, get healthy, get pregnant again plan. D&c tomorrow early morning Hmm. I feel ok... Still very numb about it all. I can't believe it happened again. I'm not asking for much... I don't want loads of kids I just want one. Is that too much to ask for??
Hope you get the phone call soon so you can at least relax for a few hours before the worry sets in again.This whole journey is absolute bull shit isn't it?! It shouldn't be this hard.

Tryingno1 · 14/06/2015 09:39

It is such bullshit. I can't believe first u have to get preg and then not miscarry and then God forbid all the other awful things that happen!
Aw, it's tmrw. I'll be thinking of u lots. I find I go into coping mode and just get on with it. The emotions hit me after. I'm so sorry :( well done for being so brave. Xxx

Seekingmiracles · 14/06/2015 09:57

I'm the same... Practicality first. Emotions later. Otherwise I just wouldn't cope.

Original poster
sunnyday01 · 14/06/2015 10:02

Thanks girls, had a bid old cry which made me feel better. I do t want it to ruin our holiday so I'm going to try and get on with it without worrying too much - easier said than done. It's only been brown so far and no clotting, plus just done tour of hotel and when came back wasn't much there so hoping its going to stop. I think I can deal with it easier if no red blood or clots.

Thinking of you trying and seeking. Hi to everyone else

OP posts:
Tryingno1 · 14/06/2015 11:04

Had the phone call. Not sure wot to think. They seem To be devolping v fast. I've dropped grades too. The embryologist didn't seem To worried or bothered and said this was quite common for things to go up and down. I can't help but think the grades will keep falling. Oh what a drama :(

Hula2 · 14/06/2015 11:39

Trying - it s so hard not to worry but if they seemed happy just try and trust in them, they ve done it hundreds of times and i m sure they d get u in sooner if they were worried you wouldn t make it to tues. These days to ET must be like torture !

Seeking hoping everything goes smoothly for you tomorrow.

Sunny - sorry you ve got this worry on holiday but try to stay positive. Rosa definetly had episodes of brown and i think Hope did also. Keeping everything crossed for you.

Tryingno1 · 14/06/2015 12:17

Thanks hula. All my top grade ones r really ahead of devolpement in terms of cells and one is already becoming a blastocyst. So they about a day ahead?! I don't know if that's ok, online some people saying it's bad and some saying it's good?? Ilol just have to wait till tmrw and I'll know more. I suppose none of them have died which is good???

Snoopysimaginaryfriend · 14/06/2015 12:46

seeking I hope everything goes well for your D&C (as well as things can go in these horrible times) and it's as stress free as possible.

sun I know it's useless telling you to relax because that fear is always there but you had a good scan, try to hold on to that.

trying what time are they doing the transfer thingy tomorrow? Yes, that's the technical term!

Oooh hula when will you start your SO (I know what that is now Grin)

So, wen, I or I should say we did something stupid last night and dtd unprotected Blush had nothing in the house and was working out in my head that surely if I was going to ovulate in my wtf cycle it surely would have happened by now. But today I did an opk. It's not positive but it's definitely close. So now I'm just hoping I was post ov or that one time won't knock me up. Do your opks have a line after you've ovulated or do they go blank again? So stupid!

Hula2 · 14/06/2015 12:57

I ll start next cycle and i m 8 dpo now so it ll be in just over a week !

Re the pos opk mine usu go blank within about 24 hrs of the peak. Left over hcg can also give false positive on opks. Have you tested out neg on hpt ? We did the same in my post mc cycle and i got ecwm the next day, it s so hard specifically not preventing after all the active ttc. I d prob make sure a preg test is neg now and then start testing again in 10 days so if you had caught then you d know its a new preg and you coukd start meds asap.

Snoopysimaginaryfriend · 14/06/2015 13:03

Oh bollocks. Yeah I did get a negative hpt not long after everything passed.

loads of women have unprotected sex for months and don't get pregnant, this is a bit weird, hoping not to get pregnant. I feel like a naughty teenager!

Does the SO increase the chances of multiples or does it just tend to make one really strong egg?

I've learnt so much on this thread

Tryingno1 · 14/06/2015 13:20

Snoopy my LH surge lasts 2 days so it's pistive for 48 hours

Transfer is tuesday!