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When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

Original poster

Immune / natural killer cell treatment when ttc or pregnant (aka the 15th pred thread)

991 replies

sunnyday01 · 06/02/2015 20:10

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

OP posts:
Drttc · 27/05/2015 18:51

The month the opk didn't work I skipped the pred. Not just because I couldn't pin point ovulation, it was also because I just felt something was off with my body. I knew something wasn't right & taking the steroids weren't going to help it.

This month I had a positive ovulation test on CD12, which is bang on what I always was before pred. I decided to take pred on CD19 to minimize cycle damage if I got a BFN this month. I've also heard of other women doing this. It's completely personal to you, and everyone's body is unique. If my cycle had not been altered before, I would have taken pred exactly when instructed. Personally, I feel like skipping the pred last month helped my cycle return to normal this time. Could have been coincidence though!

I gave it a lot of thought each month & even discussed with my husband before making any decisions. I made sure I was completely happy with my decision in the long run, so it's best to decide on exactly what you're comfortable with! You probably want to at least try the strict protocol because you'll feel at ease that first month- plus you may catch! It also may have no affect on your cycle, so no changes required! I'd see how it goes :)

Seekingmiracles · 27/05/2015 19:26

Glad your intralipids went well Sunny and good luck with yours Friday Drttc. It's fine, the nurses are used to small talk. My nurse was there 2.5 hours and it went really quick.

Glad you're feeling up to ttc again Snoopy, don't go back to working til you feel ready and be very pushy with them and what you feel comfortable doing.

I've generally always used ic opks and they've always worked for me. Generally I ovulate around cd18/19.
Obviously I didn't use them this time as I fell of between 1st and 2nd appointment with Dr S. Do the plan as you feel comfortable. I've been taking aspirin since March but I do have a slight blood clotting issue. As others have said, many Drs have differing opinions but they also have differing opinions on Nk cell testing altogether.

I'm feeling very positive for this thread ladies.... Positivity all round Smile

Snoopysimaginaryfriend · 27/05/2015 19:58

Hmmm there is a lot to think about isn't there.

I don't really have high hopes for my wtf cycle. I don't think I tend to ovulate so I don't bother usually. But if it were to happen I would want to be as far along as possible before going on holiday.

Don't worry I won't be rushing back to work. I've had colleagues take more than six weeks off for having a minor crash at less than 15mph, so I think I deserve a little more than a week to recuperate.

seeking I had intralipids a couple of weeks ago and it was funny trying to find something appropriate to watch on Netflix for two hours whilst the nurse was there, but she was very nice, she used to work for zita west.

Hula2 · 27/05/2015 20:21

Wow it s all go on here ! Great news Drttc and Rosa so pleased your scan was all good. Lets keep the bfps coming ! Trying i ve got a good feeling for you.

Afm af showed up yesterday so i need to crack on with next round of Humira (what fun....at least i can t have anymore after that !) Then should be good to start SO next month. Have an appt with Dr S to get set up next week. Interesting what you did with the pred drttc as i m convinced the 10 day course messed my cycle. Maybe i ll try a shorter course on a superov cycle.

Tryingno1 · 27/05/2015 20:34

Hi hula sorry stupid af arrives again. Glad u have taken plunge for so-I hope it works for u! U will know exactly when u ovulate so can time
Pred perfectly...hope the humira works for u this time! Did u ask mr s why they didn't go down?

Tryingno1 · 27/05/2015 20:36

Just wanted to say, we r all really
Lovely cheering Eachother on..... Glad I have u guys to obsses with :) and looking fwd to lots of BFP babies and then second babies! (Maybe?!)

Pre af emotions?!

Hula2 · 27/05/2015 20:56

Thanks trying. I haven t spoken to dr s but before i did it he said in some people the levels dont go down or even go up (5%) after 1st round but with a second round the studies showed the women still has as much sucess getting pregnant (and some more than those that didn t flare). Who knows, but feel like i ve started so i prob need to see it thru tho would have much rathered i d only needed one course but this journey is never going to be straightforward so not surprised.

Bet you re itching to get started !

Tryingno1 · 27/05/2015 21:12

I know its a hard slog isn't it, but the thread is hope for us all at the
Moment and hopefully we will have some news to add too ;). That's great that the chances r just the same-I really hope they go down for u!

Have u ever thought about ivf out of intrest?

I can't wait to start, bloddy af not here yet! The one time I want it. I think it should come tmrw then the jabs can begin. ive got a lot of time
Off from work coming up so I hope I won't need to call in sick. I feel postive about the whole
Process, I thought I would hate it all but I can't wait to get through it. I'm
Gonna be a mess in the 2ww so u guys will have to hold my hand tighthly!

Seeking thinking of u and ur bean tmrw x

Rosa27 · 27/05/2015 21:26

Trying - meant to say I've seen her when lived in London recording radio - really funny. She's also coming to Edinburgh to do an live show this year so must try get a ticket. I'm also addicted to watching Have I Got News for You on Dave. And Scandal- brilliant. Whatever helps and sees you through!

Rosa27 · 27/05/2015 21:28

Good luck Seeking tomorrow xx

Rosa27 · 27/05/2015 21:38

My DH told me he wants me to tell you all he's wishing you all lots of love and luck and even through he doesn't know you he things about you too and hopes it will work out for all of you. He made me promise I'd write this!

Snoopysimaginaryfriend · 27/05/2015 21:56

Aw rosa that is so sweet.

When I having a down moment DH says to me 'but an hour ago you were just telling me about so and so on mumsnet and all they've been through and they have a baby/ are pregnant now so you can't give up'

Rosa27 · 27/05/2015 22:09

I know it's tough for them too and they know there are more of us.. He looks genuinely sad when I tell him one of you are struggling and is also genuinely rooting for you all :)

Drttc · 27/05/2015 22:17

Awwww Rosa!!! That's so sweet!! Send him our thanks :)

Snoopysimaginaryfriend · 27/05/2015 22:42

I just texted your post to DH, he's coming to the end of a late shift, and he says it proves there are nice people out there, he just wishes he had met more of them this evening haha

Hula2 · 27/05/2015 22:55

Ahh Rosa thats lovely.

Trying we were about to start the ball rolling for ivf when i concieved my son. We ve ruled it out for no 2 as my chances would be very slim with my age and amh level and we are so so lucky to have DS that we feel it would be too much to put us all through as a family (dh definetly wouldn t go for it). So SO is as assisted as we will go so just gotta hope it works......ds just jumps at the oportunity to play with other kids at the park now and asked the other day if his cousin could be his brother.......Sad he hasn t asked directly yet for a sibling but i know the question will come soon and it ll break my heart particulary having lost the baby last year. I so hope i can do this for him.

Tryingno1 · 28/05/2015 08:10

Oh hula, I'm sorry. It must be heartbreaking when he said that I really really Hope SO works for u. Ur doing everything u can, let's hope it's soon.

Drttc · 28/05/2015 09:09

Just got my Intralipids! Am I supposed to store them in any place in particular?

Tryingno1 · 28/05/2015 09:23

I just left mine in the utility room! Don't think they need putting in the fridge...well I hope not!

Seekingmiracles · 28/05/2015 09:26

Drttc, they don't need to be refrigerated, so just keep them out of the sun.

Rosa - send your dh a big thanks from us, I'm always relaying stories from mumsnet to give my dh hope that it can happen. Big hugs to all our supportive husbands, it's tough all round.
Hula I really hope SO works for you and you can give ds a sibling, sounds like he's going to make a brilliant big brother! Smile

Original poster
sunnyday01 · 28/05/2015 11:30

flying visit - I just left mine in the box in on the kitchen floor - no special treatment required. What I did find funny is that the nurse has to take 100ml of the liquid out of the big bag and then puts the white stuff in it so it mixes up!

OP posts:
Catmum73 · 28/05/2015 11:47

Hi there. I'm a newcomer. POAS this morning and got a BFP Smile . I've miscarried 3 times this past year, and have been diagnosed with high NK cells. I've started my prednisolone this morning, and see my doctor on Saturday morning. I just wanted to check in as I'm not sure about how I feel about the roller coaster coming my way!

Would love any tips or stories.

Thanks ladies

Tryingno1 · 28/05/2015 12:06

Hi catmum and welcome and congrats. The thread is a happy place to be right now so hopefully it will send u some good luck!
Are u under Mr s too?

Seeking what time is ur scan?

No af yet Angry. Had acupuncture this am so hoping it will get it going!

Seekingmiracles · 28/05/2015 12:23

Welcome and congrats Catmum, you're in good company here, a wealth of knowledge and support from some very strong and brave ladies. Any questions - I'm sure someone here will have an answer for you. And if it's just support your after we're here too.

Come on Trying's AF!! Hope the acupuncture speeds her along!
Appointment is at 6.50..... Fingers crossed!

Snoopysimaginaryfriend · 28/05/2015 16:37

Yeah catmum congratulations and welcome!

I don't know what's up with me, I was feeling so positive yesterday but today I feel like this journey is never going to end. Every mc just kicks me back to square one.

I think I'm getting more upset because the due date for my first is coming up. I just wanted to be pregnant again by that date and instead I'm getting over a third miscarriage. I feel like there's no light at the end of the tunnel Sad