Immune / natural killer cell treatment when ttc or pregnant (aka the 15th pred thread)

[sunnyday01]

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

Hope af arrives soon Trying... how exciting that your about to embark on your new journey. Really wishing everything goes well for you!!

drttc - i've literally had no symptoms, only my boobs hurting before i started taking pred. It's masked everything.

Swnanny, Determined, it sounds like you're both doing everything within your power to get to where you want to. I'm sure it's all just a matter of time before something clicks and works for you both.

I've had yet more down cm. It's driving me insane. It goes for a few days and then comes back. With my 8 week scan looming it's making me very anxious. I just hope little bean is comfy and doing well in there.

Trying, I've used progesterone to delay AF and it usually comes in 2 days! Not sure if they've given you something slightly different.

Seeking, I read somewhere that woman who aren't experiencing symptoms while on pred should enjoy it... Lol! Maybe try to apply that perspective? Hard I know! 8 weeks is exciting though :)

Hi Drttc - sorry you're getting these symptoms, think I only had that a couple of times. I'm weaning off pred so down at 15 at mo and have less symptoms (almost nothing) than when was in higher dose..which seems odd.. Getting worried about MMC again. But compared with other pregnancies I would say nausea less with pred but fatigue as bad or worse (prob because of insomnia and cyclogest).
Trying .. I won't get Harmony tests until Wed/thurs next week... And 12 week booking scan next Thurs too. The final countdown to the first big milestone is taking ages as predicted! Hope your AF shows up do you can get your new show on the road .. So to speak! X

Rosa can't bel ur nearly out of trimester one! It's so true, ur life can change within a month. To think where u were a few months ago. The fear of a mmc will always linger I'm sure but hopefully u will feel like this is real after the results next week. I still have everything crossed for u!

Yeah drtcc that's the same thing! I was told 2-5 days...Hopefully it will come on Thursday ow have acupunture booked to try help it along! Good luck with ur test

Well it's only 10dpo but...

I got my BFP!!!

No idea how to feel, except as though I'm a step closer. The beginnings of the faintest BFP started at 8dpo... I'm already questioning what it means! Never had a BFP this early. Which means I'm only CD23... 3 weeks pregnant?! Maybe I ovulated very early! Praying this is the healthy pregnancy we've longed for. Have contacted Dr S but Louise is gone so trying to sort things with Cheryl. Waiting on her to get back to me about Intralipids. My MC tend to happens so early that I'm going to be shitting bricks for at least 3 weeks. Then I can move on to just being terrified...

Hope you all have a lovely day lol!

Oh how amazing Drttc! I really hope this is it for you :) it is weird getting a + at 10 dpo isn't it.. Mine was there on the digital 1-2 weeks- but faint on my GP's test. It's hard to get your head around but everyone thing and everyone starts at some point!:) I also know what you mean about the levels of fear. I'm burnt out from fear.. Not felt preg the last couple of days and so so worried about MMC. I've a scan later this morning ... Last one before the 12 week next Thurs... X

Congrats drttc ! Gosh this thread has really picked up. Hope u get the intralipids etc sorted. Yay!
Rosa good luck xxx

Wow that's brilliant news Drttc!!! Congratulations! You are not alone with the fear!! Don't worry! We'll be here to hold your hand as you have been for me. My mcs were always around 5/6 weeks so those first weeks were hideous, slowly it's getting better but it's still bloody terrifying! Fingers and toes crossed for you!!
Rosa are you hang NHS scans as well as with Drs? I wish I'd arranged another for next week rather than wait the two weeks to see Drs again!! Can't wait for tomorrow to be here.

Thanks, Rosa! Good luck on your scan & can't wait to hear to good news :) it's crazy how in my mind your pregnancy is flying by!

Cheers, Trying! Yes, it is really all happening now after a gloomy dry spell! I'm not liking how long they can take to get back to you... It's all urgent to me!

Thank you, Seeking! We've said it a million times but god it is SO hard to ignore our past experiences... Even now I'll check for spotting, when AF isn't even due until saturday! Going to try my best to be positive though :)

wow Drttc - that's fab news - totally with you in the scary scary phase at the moment! I'm 5 +4 today so still very early and so very scary - I can't talk about it at all, even to DH - I keep thinking if I don't think about it, time will go quicker - it's not!

I'm especially worried as still have no symptoms, but have been on the pred for a week now so guess have enough in my system to cover anything I may have.

I have my first intralipid this morning - very nervous despite having one before. find it a bit odd that they come to your house - not sure what me and the nurse are going to do for 2 hours! I'd rather do somewhere for it I think!

Well if there is any truth in too many scans make your baby left handed mine will def be left handed! Had my 9th today (one private, one with Mr S all the rest with hospital). They thought 11+2 and HB. Phew... If I can just get to next thurs with good news on Harmony test and booking scan I might start to breath properly.
So great do many now on the right path... I'm actually having to remind myself who! There was nobody for a while on this thread .. Then only Hope for so long. It's really encouraging for everyone to see that it can happen .. Even with very tricky history and profile and when you feel maybe it can't. I hope I can stay this positive .. And everyone else feels it too x

*so many

Great news rosa! I think the fact mr Shehata was so sure u would be ok last time with dropping ur steriods etc was a sign he thought u were right on track.
All the positivd news is making me excited and I really Hope I can join the world of bfp soon. I had insomnia last night which I usually get pre af so hopefully it should come tmrw.

Sunny yes let me know wot u did for 2 hours I have mine next Friday as u have it pre egg collection in ivf. Am I have no idea what u do! Have a chat?!

Just finished! Was actually all fine, the nurse was lovely and the whole experience much better than when I went to wimbledon. We just sat on the sofa and chatted about various stuff including mc as she had had 2 since having her little boy. Had the tv on in the background!

It's all so common isn't it. I think if I opened up to people many more around me prob have had similar issues. But we only hear of the ones who blink get preg, and live happily ever after.
I'm feeling postive at the moment, I've started watching snippets of comedy stand up every night for ten minutes to make me laugh! I really recommend it at uplifting ur mood! I've found a comedian I generally find quite funny. (Does this sound like I'm insane?! )

Me too Trying - hope this can be a 100% positive thread ... I'm sure everyone's time will come. Let me know what comedy you watch - I also like that. Sometime serene music etc makes me to melancholy.
Sunny - I've to get my 3rd soon though actually it's 4th as had one months back..and get someone different every time. They always chat away though and I just have a furry hot water bottle ready for my arm, cups of tea and the remote. The time goes fairly quick I thought.
Can't believe will reduce to 10 on pred tomorrow and a week tomorrow will be my last day on it.. Def put on weight though .. About a stone! X

Yeah well done drttc!!!!

All you guys are an inspiration. I'm so happy there are so many positive stories on here right now.

I seemed to have stopped bleeding and got a negative hpt, so DH wants to get straight back to TTC.

I'm very scared. We are going away to the U.S. for two weeks in September so if I'm going to be out of the danger zone i would have to get pregnant pretty soon. DH says I'm being silly, that it won't happen again, he has complete faith.

I'm trying to be hopeful but I'm scared. Simple things like doing opks and early hpts scare me. What if I read it wrong, what if I start the steroids on the wrong day? What if an early positive is just a chemical? What if I struggle to get pregnant on pred, DH is used to getting pregnant every time we try.

I'm still not back at work. I told them I'm not working shifts and I'm not dealing with anything so stressful anymore and my line manager has agreed but no one has taken any steps towards identifying a new position so I'm in limbo.

I'm also concerned about taking aspirin every day as some doctors seem to think it hinders implantation but I have been taking it. What were your experiences?

Sorry this post is so me me me, but I think only the people here will understand.

I have me fingers crossed for all of you.

Congrats Drttc! So pleased for you and all you ladies with your positive news! Who hoo

I'm glad you are not back at work yet snoopy...you are doing the right thing by making some changes there! Re aspirin diff docs believe diff things so I think I either go with my gut or do what my doc says so I've done everything but the book! It's a hard one with so many ch conflicting info

Xxx

Thanks, Sunny! Glad to hear your Intralipids went well :) Ive just booked my first Intralipid for this Friday... Was surprised I sorted it so quickly lol! Guess I'll have to tidy now... When is your first scan?

Rosa- yay on your scan!!! Sooooo close to the 12 week mark. And your harmony results!

Thanks Snoopy! Hope you're okay. It's very scary going back to trying after experiencing loss. We understand and will be here for advice.

Cheers Determined :)

You know, I also think the stats they have on loss are well underestimated. It's a tough subject to be open about as people don't want to bring others down... But I agree that a lot more people than we expect are suffering silently (even from their GP's).

Hi snoopy. The asprin thing is a huge debate and people have different views. I spoke to mr SHehata about it and he said it was based on one study that he thought was crap! He pointed out most ivf units use aspirin-which is true. Well mine do regardless of immune issues or not. So pick a a side u feel
Comfortable with and go for it! Most
Of us on here were fine with pred-think drtcc and hula felt is affected their cycles.....

Rosa I listen/watch to Sarah micillian. I find her hillarious. Just 5 mins at night to get some endorphins going!

Well I guess I will respect DHs wishes and follow Dr S's plan to the letter. It's definitely working for lots of people here

Well you guys are going to get bombarded with a hell of a lot of pictures of opks with the question 'is this positive yet?' Haha

Hi again Snoopy- just wanted to say that yes pred definitely affected my cycle. I've always been like clockwork then suddenly the month after taking pred I couldn't detect ovulation (no fertile CM except for on CD7!) on clearblue digital ovulation kit, started spotting early on (unusual), and had only a 23 day cycle.

Because I suspected something wasn't right I skipped pred during that weird cycle (last month), and everything went back to normal this time around. I started pred on CD19 this month & was going to stop after 4 days if I got a negative test. But got a BFP :) So still on it!

That's ok snoopy post away! The clearblue ones r exp but give u a simple smile or not! I used ones from home bargains and they were my fav. Tested at 2ish after holding wee for 3 hours and not drinking. Always got a postive on a day 15. U will see the lines darken every day.
Don't panic if u don't get a postive sometimes People miss their surge etc. I know some women haven't used Sticks and just take pred day 16/17 as most women would have ovulated by then.

Snoopy - I almost religiously followed Mr S plan too.. But I did wait until BFP to start asprin (as no sticky blood issues) and I also waited a day or two after ov to start pred so was taking a bit less each month and to hopefully not affect my cycles (it didn't). So that could be an option but of course your choice and I'm sure the total religious following of the plan is better .. But you do also have to feel good about waft you do. All the best and bug the hell out of your work to sort the new role out ASAP. X

So did you just guess what day to start from your average cycle length drttc if the opks weren't working.

I tend to have a 33 day cycle and seem to ovulate on day 19 when things are working.

I've got some internet cheapies so I can pee away and not worry about wasting them.