Active discussions

Meet the Other Phone. A phone that grows with your child.

Meet the Other Phone.
A phone that grows with your child.

Buy now

Please or to access all these features

Talk
Conception

When's the best time to get pregnant? Use our interactive ovulation calculator to work out when you're most fertile and most likely to conceive.

Original poster

Immune / natural killer cell treatment when ttc or pregnant (aka the 15th pred thread)

991 replies

sunnyday01 · 06/02/2015 20:10

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

OP posts:
dildoos · 12/02/2015 22:35

Trying it's sad that we become like this but feel we do to try harden ourselves to the blow. So at month 9 has given you a fair chance to fall without! I keep everything crossed that you won't get to that stage! Hope Monday goes well xx

Snoopysimaginaryfriend · 13/02/2015 16:33

Hi everyone just thought I'd update.

Had some light brown spotting but seems to be getting heavier.

Waiting for hcg tests but know in my heart it's happening again.

I'm scared no one will ever call me mummy.

dildoos · 13/02/2015 17:29

Snoopy, I know it is very hard but try stay calm. Are you to up your cyclogest? What's your hcg level at present? How many weeks are you? We will all cross everything for you! X

Tryingno1 · 13/02/2015 17:52

Oh snoopy I'm so sorry. I know it means nothing to us who miscarry but spotting doesn't mean it's all over. Loads of women do...how far along r u? Have u spoken to mr s midwife?
Don't worry, someone will call u mommy it's just ur journey is going to be longer and tougher. But they will and u will be a lovely mummy. (I worry the same too, but we both will get there just who knows when).

Snoopysimaginaryfriend · 13/02/2015 18:41

I'm only just over five weeks, so I guess it wouldn't even count as a miscarriage.

Just did the first blood test.

I don't want to pry but any of you had the full range of tests from Dr s and how much did it cost

Tryingno1 · 13/02/2015 18:47

Any loss after a postive test hurts no matter when it happens....

It cost about 2 grand. I got all my standard stuff done by nhs like thyroid, lupus and uss etc. have u had these done by the recurrent miscarriage team at ur local hospital? I then had nk cells etc done with mr s.

Try be positive if u can, I really hope the bloods are promising. Loads of ladies spot all through pregnancy and have a happy healthy baby. Will be thinking of u this weekend.

Seekingmiracles · 13/02/2015 19:32

Hi ladies... I will read back throughout promise.
Just wondered if any of you had any experience with Dr Shehata. We have our first appointment with him in April after 2mcs and a cp.
What can I expect? Had full thrombophilia screening with nhs and nothing has come up. Convinced I've got high Nk cells. Thanks in advance Smile

Snoopysimaginaryfriend · 13/02/2015 19:35

The thing is if this is going to end badly it will technically only be my second miscarriage. My gp was great and did my thyroid antibodies what else should I ask them for.

Is that just for the NK cells trying?

Thank you all for your kind words. I've actually stopped crying for the first time in ten days.

dildoos · 13/02/2015 20:12

Had all testing with dr s in October cost us £1850.
I ha chromosome testing on Nhs but dr s said it's a really dated test that means nothing really now.
I have high functioning nk cells so not over amounts but the ones I have over react to pregnancy and the more miscarriages I have the worse they will get as apparently like my body is going into anaphylaxis every time I get pregnant.
He is a clever clever man x

Tryingno1 · 13/02/2015 20:14

Seeking-hello, sorry u find urself going to mr s. best thing if to get all standard tests done by gp/ur recurrently miscarriage clinic to save u money! So-lupus,thrombophilla,thyroid, pcos, prolactin (uss and blood tests) amongst others I am forgetting! When u see mr s, he will go through ur history. And send u for some blood rests down the road-they cost about 2 grand! 2 weeks later u meet him and he plans tx with u! Lots of ladies have had sucess with him, but currently we are going through a rough stage on this thread. Apart from hope who is 20ish weeks preg with a boy after 7 miscarriages. Yay for hope!

Snoopy-try be postive. Try not to plan what to do if this one ends. Bean needs u to happy! I don't know if ur gp will do another tests as its not the majic "three in a row" but its the ones above I've written....rem most miscarriages are one of events and no cause....hugs. Sorry ur going through this uncertainty. I forgot, how old r u?

Tryingno1 · 13/02/2015 20:17

He tests nk cells and ur tnf status (it's either high or low) and I think ur th1 and th2 levels. So it's basically an immunology work up. It's the same tests they do for ivf patients who fail to implant/recurrent ivf failures.

I have high activity of nk cells (just) but nk levels are normal. My tnf levels are also normal.

I went to him after my third miscarriage. After my second my routine nhs tests came up normal. I tried again, miscarriaed my third and went to see mr s.

Seekingmiracles · 13/02/2015 20:25

I've had most of the nhs tests and they've all come back normal so far. Got an ultra sound next month at my follow up consultation. Hoping DrS can shed some light on immune issues. DH nearly just spat his tea out at the cost! Haha! But I'm very much in the 'fuck it' mindset.
Yay for Hope indeed, I hope everyone else has more success soon. This heart break is unbearable.
Thanks for your insight Trying Smile

Tryingno1 · 13/02/2015 20:38

Good luck seeking! One thing that mr s did do with my tests, which I didn't think of at time was test me for TB. That's incase I needed humira if my tnf was off. It wasn't, my tnf was normal, so I didn't need the TB test. Which I'm sure will have been a good few hundred. He could have tested me for TB if my tnf was off after, obv would have meant a good 6 weeks delay before I started ttc...but just a thought incase u really need to watch those pennies!

It is a really hard journey. I've suddenly lost the ability to get preg after 3 quick pregnancies and don't know wots going on. It's all pretty shit really. (And its not mr s plan (to take pred post ovulation before a bfp) coz I was a naughty patient and only followed it for 3 Months and haven for the last 4). So not sure what's up. Not my time for a baby yet I think.

Seekingmiracles · 13/02/2015 20:45

You'll get there Trying. I've fallen pretty quickly each time too... Generally 4th cycle after each MC. I'm paranoid that I'm now going to have issues falling again. There's always a worry isn't there. The thing that upsets me the most is the fact that I have all this worry. When most people have a generally worry free time getting pregnant and miscarriage doesn't enter their innocent little mind. Oh to be one of them! Hmm

dildoos · 13/02/2015 20:52

Seeking- I also thought that, but what I have found is that us who try so hard to be mummies are in the end so grateful of the gift of motherhood that we treasure them moments a bit more, I don't mean that the falling straight away don't treasure their children as the absolutely do, however I have 2 friends that will often agree that I stay calm, I guide, I allow messy play, I take time to do homework, read at bedtimes all those things I treasure and feel guilt of I don't do something as a mum as well as I could. We don't take any part of motherhood for granted. When all you lovely ladies get your turn at motherhood you will see how your parenting comes so differently to that of others xx

Tryingno1 · 13/02/2015 20:58

I know wot u mean dildoos. I've always thought, I can't imagine complaining when I'm fat and preg, or when I'm sleep deprived coz I'll have wanted it so badly and cried so much for it. But then maybe I'm being naive and all this will have been a forgotten memory when I have my baby?? I don't know!
Oh I know seeking, my first preg-I got preg 2 months was so naive and immature! The thought of miscarriage wasnt even in my mind! I was so jammy. Came tumbling down very quickly. How old r u if u don't mind me asking.
Good luck for ur appt when is it?

dildoos · 13/02/2015 21:03

Trust me trying it won't be a forgotten memory, they prepared me for 8 months that I was going to loose my little miracle and I prayed and prayed and she is almost 7 but there is never a part of me that forgets how lucky I am, I I never have another I have her to be grateful for. You all will too! You won't forget your to lovely to forget to be grateful x

Tryingno1 · 13/02/2015 21:08

Thanks dildoos. This whole situation has really made me think about life in a diff way. U dont know wots around the corner and things can change so quickly. I'm aware things can be so much worse too - so am grateful for a healthy and lovely DH and parents and brother. Hopefully when my time comes I'll really savour it, be grateful and a mature grounded mother. (Although I worry this whole exp is going to turn me into a anxious OTT mother who won't let her kid out of their sight!)

Snoopysimaginaryfriend · 13/02/2015 22:11

Trying I'm 29.

Gosh dildoos that sounds so scary, but if your body has done it once I'm sure it can do it again, it's just trying to get through all the setbacks and heartaches.

I'm bleeding now so I think this is it but I will have the second blood test in case of a miracle.

DH has already said we will try again.

I'm worried about work. My lovely gp had already signed me off until the 3rd March but my first day back is officer safety training.

Do you think that working shifts and the hypothyroidism could be having an impact?

From tomorrow I'll get back to my healthy eating. I think it helped me conceive quickly after the last mc. A green smoothie everyday!

dildoos · 13/02/2015 22:21

Snoopy I hope that the bleeding stops, feet up oxygen to the uterus and all that ! Takin it easy at work is always a good thing I be doing.
Is your next bloods Sunday? Did they not give you your hcg levels today? X

Snoopysimaginaryfriend · 13/02/2015 22:34

My mums lovely phlebotomist friend did the test at home this evening and dropped it off to the pathology lab at the hospital. I've been crying going to doctors, hospitals etc so this was better for me.

Snoopysimaginaryfriend · 13/02/2015 22:38

Should I use cyclogest this evening or is there no point, it all started too late for me to contact Louise.

I guess DH and I will have to discuss if we go for further testing. My mums pretty good at demanding things from gps so I will try that as well.

Tryingno1 · 13/02/2015 22:45

Snoopy keep using it. It won't do any harm and u would kick urself if everything turns out to be ok.

Ur thyroid should be well controlled , but I don't know at what level I'm sure mr s would tell u.

U could get ur Gp to do usual nhs tests-he would know most of them that need doing. 50 percent of time they are normal though.

Shift work I never know-people get preg and stay preg under the most awful stressful situations so I don't think it's linked...but I can't help but think stress might play a role. I don't think Anyone knows. When ur not at work look after urself and relax

Seekingmiracles · 14/02/2015 08:50

Trying I'm 30. I know I will treasure every moment of motherhood. I won't moan about trivial and inconsequential things. I will love all the mess, sleepless nights, tantrums along with alle lively moments too.
Snoopy - I really hope the bleeding stops. Thinking of you today.

dildoos · 14/02/2015 09:10

Snoopy how is the bleeding this am?
Have you called Louise?
Hi to everyone else.
X