Immune / natural killer cell treatment when ttc or pregnant (aka the 15th pred thread)

[sunnyday01]

This is a thread for those diagnosed with high or very high natural killer cells and trying to concieve or are pregnant and taking steroids/intralipids etc

Newcomers very welcome

I know.. I am still utterly petrified. Just had a wee cry as keep sensing cm and worrying is blood.. It is a little tinged and hoping it's the cyclogest.
Growth was up 5mm since 6 days ago - 11 now which was told to be right for 7+1 (thought was 6+6).
I really can't imagine being being more of a nervous wreck. I think I need to find some mental health therapy - seriously. Thanks for ongoing support xx
Anything new with anyone else. Hope you're all doing ok xx

Rosa, this may seem a bit gross but have you considered inserting progesterone from the 'other' side? It's so much easier! There's no mess (just disappears) and no confusion over whether it's causing spotting.

Scan sounds like it went so well!

Yay, so excited to read your post Rosa. Such great news!!

Sounding positive from you too Drttc too! When do you think you will test? X

I'm not sure when to test. I have a 26 day cycle and last time I was pregnant I tested negative on day 25 so assumed I was out... :-/ I'll probably start around cycle day 23 and obsess for a few days!

I came across such a relevant quote today: 'Fear does not stop death, but it prevents life'

Drttc- your post about you didn't show when I wrote earlier.. Definitely not signs to ignore. The clear blue picked up for me on day 10.
Thanks off reminding me there are other ways. Have heard some other unpleasant side effects from the other route. I might try though. In my head I thought it might be more effective if closer to the uterus. So nervous of doing anything wrong .. X

Hope how many weeks are you now? Do you have any other big milestones before the major one? :) x

rosa with my DS I was using cyclogest in the 'normal place' and started to bleed at 6 weeks but it was a light brown colour. I was convinced I was miscarrying again and would never have believed I would be sitting here looking at my healthy 3 month old son! I switched the cyclogest to the bum and the bleeding stopped. It apparently doesn't make any difference where you put them plus i didn't get any side effects. I also noticed that there was less after spillage up the bum!

Thanks Suemays. I will prob do but might wait to check with Mr S etc assuming make it to that appointment on 11th., just because I doubled my dose after seeing brown and nothing really since. Touch wood. I've felt chronic fatigue today - not helped by waking at 4. No other symptoms though which of course is worrying me as felt bit sick and sore yesterday. I've been ok before twice at this point .. If only could speed up the next few weeks, and months. I read online after seeing a heartbeat at 7 weeks miscarriage risk is 2% but 18% if you've had recurrent miscarriages. And it goes up at but more for my age. Hm.. Worry, worry, worry! X
Happy Weekend all xxx

It is so exciting Rosa! It isn't just the heartbeat but that the baby is growing well and sac and everything looks good. I know it is a long haul, but all is where it should be right now and really think this will work out for you. Remember I had no symptoms at all on the pred until about ten weeks then I had awful sickness until 20 weeks. I'm at 28 weeks now so getting closer! I have a huge bump, indigestion and insomnia! Roll on 40 weeks!

Oh Hope I really really do hope you're right. I have more very very light brown tinged cm this morning. It's so worrying as this fortnight has never been good for me and that colour was a signal .. I just don't know what to do to stress less .. I get a few hours peace after a scan then for all I know it's going wrong. X

Ps absolutely delighted got you .. You really are well into the last trimester ... So, do happy and excited for you xxx

Hi ladies,
Hope you don't mind me popping on.
I'm currently under Dr Shehata having been diagnosed with high NK cells on Monday of last week. At the first appointment (2weeks prior) he'd told me not to get pg.... But low and behold last Thursday I did a test and it was a bfp ..... Queue panic!!
At Monday's appointment I told him and we started there and then with my medications:
Clexane for PT gene variant
75mg aspirin
400mg cyclogest
25mg prednisone

Today I'm 5 weeks and worried that aside from my boobs feeling marginally tender I have no symptoms. He did say that the steroids can mask the symptoms, has anyone else found this.
I have a scan a week Monday so hopefully that'll ease my worry a bit.
Thanks in advance

Rosa everything sounds like it's right on track! You're not describing symptoms that would cause anyone to worry... We'd tell you!

Hi, Seekingmiracles! Congratulations on your BFP! What's your history, if you don't mind me asking? Will you do Intralipids as well? X

Hi Drttc,
Thank you .... Very nervous as you can imagine but hoping everything will go to plan this time and the meds do their thing.
History: MC at 5+2 Dec 14, blighted ovum June 14, CP Oct 14. NHS diagnosed the pt gene variant but I wasn't convinced that was the sole reason for the mcs, hence the visit to DrS.
Trying to catch up on the thread so excuse me while I try and figure out everyone's stories.

Oh and yes... Got intralipids booked for 14th May (6+6) if all goes to plan

Hi seeking miracles congrats on yout bfp !

Drttc - sound like you ve had some promising signs, fingers crossed this could be your bfp.

Hey this thread is hotting up !! Keep em coming ladies xx

Hi seeking miracles ...welcome & congrats! As you'll see if you look back I'm anything but calm but (hopefully still) just over 2 weeks ahead. I've just felt some sickness, increased hunger and extreme tiredness over the last week or so but it fluctuates a lot .. And as everyone rightly reminds me every pregnancy is different and what's bad news for someone might not be for another. I'm training myself to sing que cera in my head over and over because all the stuff I can control is in hand .. I'm sure you're in great hands and have the best possible chance of success this time x

Hi Seeking Miracles, and congrats on pregnancy. Pred really masked my symptoms with this pregnancy. I was convinced I had miscarried at seven weeks for that reason but all was fine. No sore boobs, no sickness, just cramps! I was freaking out. It was very different to my previous pregnancy which I didn't take pred for. I have had seven miscarriages and have one son and am now 27 weeks pregnant with second one at almost 39, x

Thanks ladies,
I spent ages reading back last night so I'm a bit more up to date with where everyone is at now.
Congrats to you too Rosa and Hope.
Hopefully we'll both be a bit more confident when we get a bit further along Rosa!
Hope you must feel a bit of relief now, although I'm sure it still won't feel real
Until that baby is in your arms.
I hate how MC has made me such a nervous wreck but as you say Que Sera, sera... What ever will be, will be. We're all in expert hands!

Question...With cyclogest, does the remains of the pessary leak out if it's done up the bum?? I'm thinking of switching as feeling it leak out is really stressing me out. Sorry for the TMI!!

Seeking miracles I can really relate to that feeling of frustration at how much of a nervous wreck RM makes us. I am normally a pretty relaxed sort of person and thought that would carry through but I am still quite anxious. I still look for bleeding for example every time I go to the loo, which isn't even logical at 27 weeks (!) and always get worried about baby's movements even though he's usually kicking up a storm. Having said that I am much, much better than I was during the first 12 weeks as at least I can enjoy it now as well as feeling a little stressed.
I swapped between front and back with the pred.i didn't like the leakage at the front and thought it might be making me spot, but the back way made me even more constipated than I already was. Oh the joys! I never really found a good solution to be honest but was v.happy to stop it at 16 weeks. The pred made me look seriously gross too and that improved after 12 weeks, although have obviously looked better in my life unlike Duchess of Cambridge. She looks amazing but surely must besting inside to have pulled that exit off. I could barely walk after the birth of my so and I have a horrible feeling she was wearing heals. Bloody hell!

P.S. How are you feeling today Rosa?

Think i'll make the swap tonight and see how I find it.
It's so unfair that we end up feeling so crap and nervous about being pregnant/ ttc when so many people don't really even give it a second thought. I've found that one of the hardest things to deal with. I'm jealous of all those who get pregnant easy and have not a care or worry in the world through out.
How on earth did Kate look so bloody amazing?!! There must have been a tornado of hair and make up people tending to her! And heels??! Jesus!!

Ha I was looking at pics if Kate thinking the same.. She certainly will have had every top therapist and beautician in the capital at her disposal so that must surely help.. Plus her whole pregnancy would have been much more stress free than anything we can hope for which helps too!
Hope - I'm ok today .. Barely moved yesterday (discovered Cuckoo bakery in Edinburgh does gluten free banana and salted caramel cup cakes- amazing, you have to try!)
Hoping I can at least walk for half an hour - I'm piling on the pounds I fear already. With cyclogest, while could really do without more constipation I do want to try switching .. But really worried about it not being as effective as the brown scare was dealt with when doubled the dose.. But that may be a coincidence. I will feel a little better if see reassuring scan next week, and a lot better if see one end of the week after or around 18/5 which would be after the time my longest pregnancy stopped growing. My birthday is just before that and not sure what to do.. Not told anyone but have a twin bro who will notice I fear... And would rather not bring anyone else into my nerve wracking limbo. RM is so much harder than anyone can imagine- it really affects every part of your life and I do hope there's more support for people like us in the future. I'm so grateful to have found this forum x