TTC Super Ovulation part 3

[Arianrhod]

Hey ladies -

There are a few of us who are ttc after mc's, however there will be ladies out there who are also ttc for the first time or second or third without success. If anyone is on, considering or had success on a super ovulation programme then do join us. How long did it take ? Did you try IUI with it.. ? Did you have PCOS?

Kicking this off and hoping some of you will join....

part 1 here:
www.mumsnet.com/Talk/conception/1385998-TTC-Super-Ovulation

Part 2 here:
www.mumsnet.com/Talk/conception/1475108-TTC-Super-Ovulation-part-2?pg=1

Sorry about the bfns :( xx

Just joining here as Duggs kindly sent me the thread having asked the question on my behalf!! Thanks for all super advice on humira... wanted to asked Choccypud how you felt when taking Humira and did you have any side effects... I was told humira stayed in my system for 6 months and then my TNF's rebalance again but anyhow it is months rather than weeks. I am pleased to hear you don;t think it has any effect on subsequent pg's and really looks like you act fast whilst it is in the system in actual fact

Just to say welcome callincusp x

Just the rather aggressive allergic reaction rash I've described previously...!

Totally devastated. AMH results back and they couldn't have been worse. 1.5, in the very low/undetectable region. The mystery is solved, and I never thought the answer would be as banal as that. And my FSH was still in the ideal region! I think that's going to be it for us now as there's no point throwing good money after bad. :(

brown So sorry to hear of your results .. this is exactly why I'm not getting my AMH tested. With not great FSH I'm fairly sure my AMH won't be great either. But you know, if you read the Fertility Friends forums there are many stories of women with lower AMH than yours still getting pregnant. Medical science doesn't know everything, clearly. Will you definitely give up on this, or could you perhaps take a little time to think about it? Big hugs to you and whatever you decide remember we're here for you.

brown I just did a quick google on AMH 1.5 and you know, there are LOADS of posts from women who had this or lower and still went on to have a baby, either ICSI, IVF or even naturally. I found this part of a longer post and thought it might help you a bit:

/quote
Plus, as others have mentioned, AMH indicates numbers and not quality so if you are 35 or 40 plus your AMH will be lower. That is entirely NORMAL and any 40 year old conceiving naturally is likely to have low AMH. The key is egg quality and, as with everything, some people may be luckier than others in terms of how well their eggies age. But there ARE things you can do to make sure you produce the healthiest eggs possible and give yourself the best possible chance.

Good luck to all and try not to obsess about your AMH!

/end quote

Brownstag, if it helps at all I had my AMH levels tested in May and they came back 2.04, so also in the low/undetectable range. I was devastated, despondent, hopeless etc. 2 Months later I got pregnant.

Thanks ari, I appreciate that. My dear little boy kind of understood why I was crying this evening and he drew me two cards, one of a baby and the other of a tray of eggs! I had to laugh.
You know there are two scales for AMH, and my one was the one using larger numbers so 1.5 is probably virtually nothing on the other one. Plus it would have been artifically high because of the DHEA! Christ knows what it'd be like normally!
Obviously I will think about it more but there is a little bit of me that is almost relieved, to be free of this enormous obsession ...

havingkittens, really? Wow, that does give me some hope. Which scale were they using? On this one 40 to 60 is 'ideal'.

This is how mine reads;

0 - 3.07 - low/undetectable
3.08 -21.97 - low
21.98 - 40.03 - satisfactory
40.04 - 67.9 - Optimal

There you go, same scale as kittens. Who gives us 'oldies' all hope :)

And remember, DHEA doesn't affect AMH - AMH is quantity of eggs not quality, DHEA doesn't give you more eggs, it (sometimes) improves the quality of eggs you have.

DHEA definitely does increase AMH; there are lots of studies showing that, with graphs :). Which makes my results all the more horrendous.
How old are you Kittens?

I'm a couple of months off 43.

brown I thought AMH were meant to guide how aggressively they treat you. I know your levels are low and that is quite devastating but give yourself some time to think about it. Mr S encouraged me to get my AMH levels done and I was gutted when the result came back, but he said they were OK. What did Mr S say about yours? It took me at least a couple of days to get my head around the fact I did not have the fertility of a teenager!

I think it was Choccy who appeared and gave her expert view on my results. Remember it just means that your stores are low, but it only takes one egg.

hmm Ok, I didn't know that about AMH. But I still wouldn't put too much store in the AMH value brown, honestly.

I meant I didn't know that about DHEA. Can't type worth a damn tonight.

Lemon, I didn't get mine done by Mr S, but a company called DuoFertility. I rang their fertility advisor to discuss the results and she seemed surprised there was so much discrepancy between my FSH (7.8) and my AMH. So it might be worth retesting. Also my results had been delayed as there was some kind of problem and they had had to send them to a different lab. She was going to find out what that problem was and whether it might have affected the results.
Incidentally, she said normal for a woman of my age was 3 to 9.
But I also googled AMH and endo and find crap AMH is highly correlated with stage of endo, of which I have the worst stage.
Assuming these results are right, I don't think I can face the panic and desparation of ttc in the face of dwindling egg supplies ... knowing I really need IVF and can't afford it.

Hi there. Old poster here lurking from time to time. I wanted to encourage you, brown, that a low amh isn't the end. Mine was 0.67 (same scale as kittens) in sep 2010 and I have conceived twice since then, both times via super ov. I was devastated when that result came through, so I understand your concern, but both mr S and my acupuncturist were not concerned at all.

Wishing each of you on here well x

Think ill go buy some dhea but doesn't mr s not rate it? How much should you take?
I'm sure the levels change I remeber being told I was premenopausal but then the next month it was better as it wasn't long after mc.
Those ladies who have had the tnf test, how early in themorning can you have blood taken? Is it just 1 tube? I live in York but hubby goes to Harley st once a fortnight but leaves at 1.30 am so don't know if I could get someone to take blood that early then him drop it off at 7 am or if it won't be any good. I can see me just going to London again :/ why can't they do it at Surrey?
Another tough time on this page this week so wishing you all a lovely weekend, hugs and strength in whatever you all decide xx waves

Thank you everyone for your support. All night I was tossing and turning dreaming about AMH.
mel, mine come from Vitasunn, they take a couple of weeks to arrive from the US. Most studies use 75mg, but I started on 50mg to see what happened. On 75mg I have bad acne, including on the scalp and very itchy, increased sex drive, vivid dreams, increased fertile CM, better sleep and a feeling of well-being. I probably only had all these benefits because I was actually premenopausal I now realise!
Yes, I think it's about 4 or 5 stops on one line from Charing Cross to Regent's Park (Bakerloo?), then you turn left, cross over one small road and the next road on your left is Harley Street. The tube part takes about 10 or 15 mins and the walk about ten mins tops.
What I don't understand is that if there's a correlation between reduced ovarian reserve, low AMH and endometriosis, why when I google endometriosis and early menopause nothing comes up?

Brownstag I know you are disappointed with your results but a friend of mine who is in the same situation as us conceived her daughter naturally after finding out her AMH was 0.something. It definitely can happen. Also panic over about the dodgy Pred from my post a couple of days ago. I saw my friend yesterday and she is taking suppository ones, so not the same type as us.

Brownstag, I think you should wait until you get a chance to have a chat with Mr S before getting too worried. I really was in despair about mine and made my own assumptions based on the ranges quoted. All of my results were in the lower end of what they should be, or in the case of FSH, higher. I then gave myself a talking to and reminded myself that I was a Make up artist trying to draw my own conclusions from my results and what I really needed was a doctor, at the very least! Mr S was far less concerned than I was and put me on a combination of Tamoxifen and Gonal-F, which worked.

Thanks BellyD and HavingKittens. I will talk to Mr S again. I now have a vague date for my laparascopy, early January, so I will have that, and then talk to Mr S again. I am hoping to get another FSH test at my doctor's on Monday. What I don't understand is why I've responsed reasonably well to letrozole before, 1 follie on 5mg and 4 on 7.5mg. Shouldn't I be a 'poor responder' with such rubbish AMH?