TTC Super Ovulation part 2

[suemays]

hey ladies,

There are a few of us who are ttc after mc's, however there will be ladies out there who are also ttc for the first time or second or third without success. If anyone is on, considering or had success on a super ovulation programme then do join us. How long did it take ? Did you try IUI with it.. ? Did you have PCOS?

Kicking this off and hoping some of you will join....

part 1 here:
www.mumsnet.com/Talk/conception/1385998-TTC-Super-Ovulation

Interesting. She did say that the official stance on these other infections (I think she was talking about ureaplasmas and mycoplasmas) was that they were of no clinical significance.
Yes, Royal Mail, and it cost the princely sum of £2. I didn't go for recorded. After spending hundreds on stimulating my ovaries I was suddenly afflicted by parsimony in the post office.

Arian, that is interesting. I guess we all have something that is triggering the increase in NK cells. Infections in some of us, possilbly precancerous cervical cells in me, autoimmune conditions in others and so on. I wonder if treating the cause will be more successful for us than treating the effect? I did find a study somewhere on some of these infections (not hidden C but the others) which indicated that they were found in around 30% of infertile women and 15% of fertile. Which suggests that they have some role to play in fertility, although it might not be black and white (in that those who have the infections have fertility problems).

Ari sorry to hear that, but hope treating it helps. I've got an appointment for DH on monday, the earliest I could get. The GP I saw seemed more concerned with the 25 days than anything else, she said it would normally only be prescribed for 1 or 2 weeks.

I'm utterly confused today. We had an appointment with an IVF clinic that is part of an NHS referral, and he basically said the whole reason we are not getting pg is down to my eggs. He said the fact that my amh is low, i have less than average antral follicle count for my age, and that i needed a lot of stimulation with the last ivf round point to a likely low number and therefore low quality of eggs. He also said FSH levels were meaningless. This almost exactly opposite to what Mr S told me last week. I was hoping to do the anti b's and give it a few natural cycles to see what effect they had. This doctor has scared me into thinking if I don't do IVF immediately it will never happen. He also said that while IVF normally he would give a 40% chance of success for me its just 25%. I really don't know what to do. Am sure i need to sleep on it, but just needed to vent somewhere. Any thoughts much appreciated. Why can't they all fricking agree its so frustrating.

That does sound frustrating Care. What was your AMH, etc? And how old are you? (If you want to share these details.)

My amh was 8 and I'm 34.

CareBear, that must be very confusing and upsetting. I think I'd be inclined to trust whoever gives you more confidence. It's stressful enough having to go through all this treatment without being made to feel more desperate. I looked at the Create website earlier, incidentally, and there really are some inspirational stories on there. It just shows that there are always more options, whatever someone's situation.

Sigh .. So dragged OH up to TDL for his tests and the two of us to have blood tests, and just been told that they only do these blood tests on Mon to Wed. I did ask when I rang to make the appt and was told we could come in for these tests any day. OH is now fuming that he's taken off a half-day from work and we have to come back another day. Going to be difficult to get him up here a second time :(

Care I'm no doctor but your AMH level looks just fine to me? Have you thought of getting a second opinion?

I agree with Arian,Care that really doesn't look particuarly low to me. I thought you had already tried IVF? (It's at times like this signatures would be really helpful on MN!)

Arian how frustrating.

Care, yes, when I looked up AMH levels I was confused because yours seemed okay. Are there two different scales?

Ari grr how annoying, what is TCM?

Thanks for the replies, this has sent me into a bit of a spin.

I think there are different scales - on this one 15 is satisfactory, cant recall what good and very good was, very low was less than 3 I think. Mr S said the AMH was meaningless and an old school test, whereas this guy actually said to me 'dont wait'.

Yes euro I did IVF last year and got 9 eggs and 6 embryos which were all normal. Didnt implant on fresh or frozen rounds. This guy said my egg quality is probably low and he wants much more than 9 eggs!

Sorry for me me post, am very confused and now very worried about what the best thing to do is.

Sorry ari that was meant to be what is TDL?

Ps started the anti b's yesterday - no stomach upset so far

care I had mine tested by Mr S last year (annoying that he now calls it an old skool test when I paid to have it done at his suggestion!) and it was 12 on the same scale, with above 15 being normal, so 12 fell into the low fertility category. Mr S dismissed it saying it was fine. I was 35 when I had the test.

9 eggs and 6 embryos sounds like a great result. I thought that getting loads and loads of eggs meant that you were likely to be getting poor quality eggs? I think my friend got 30 eggs (!) but "only" 6 embryos from that. If you are making embryos, and embryos that survive freezing and thawing at that, I am struggling to see how that leads him to conclude there is an egg quality issue. But of course, I am not an embryologist, so what do I know?

Sorry to change the subject temporarily, but while I remember it, with the antibiotics from the Athens test, wouldn't Mr S prescribe them if we asked him?

Possibly, he seems quite open to giving prescriptions, but I did discuss the Athens test with him and he dismissed the whole thing

So just temporarily back to amh etc, Euro you make wise points as always. Thats what I thought before seeing this guy. I'd be interested in gorgys view on amh vs immune - DH got v cross when I suggested seeing him too and thinks we should stick ti one thing at a time. Euro what was Mr S plan for you next?

I hope you don't mind girls if I intrude your thread quickly to ask Carebear a question !

Care bear - I'm honestly not stalking you (!!!) but your name always catches my eye as I know you were thinking about going to the Agora. Can I be incredibly nosy and ask if that was where you were told about your egg quality ?

Reason I ask is that our first cycle with them has just resulted in a BFN .... ! I have very very similar statistics to you (age 34 - AMH 9 - Eggs collected 10 - Fertilised 6 - although none were suitable for freezing).

We do have a 'follow up' appointment arranged in 10 days or so. But obviously I'm too impatient to wait to speak with a consultant and am on a one woman mission to diagnose our failure myself .......... ! (I know, I know) I've made an appointment with Dr Gorgy in a month or so (it was immunes or the Maldives. Immunes won ..... !)

And thanks to here I'm now thinking of sending menstrual blood to Athens ..... !!! (I've never even been to Greece myself FFS !!!!!)

Hope you are otherwise well xxx

care I have no idea! I haven't actually seen him since around March, when he gave me a prescription for Pred and Clexane to take alongside IVF and wished me well. Of course, we postponed IVF (and we had decided not to take the CLexane anyway) and now I have had the abnormal smear while I am on my post-6 months Pred break, I am reluctant to take anything to suppress my immune system until that is sorted out.

We are booked in to see Gorgy soon to get more immune testing done (including the infection stuff) and taking a couple of months off ttc. In the autumn we'll review what to do next.

Hello, super ov-ers. I'm joining you again! I was on SO Oct-Feb, fell pg on the 5th cycle, and miscarried at 10 weeks . Back on letrozole tomorrow. I had normal NK cells and then tested High while pg an then recently tested 'borderline' so will be starting Pred with a bfp. I see on here there are a few other tests some of you are taking. I'll have a long read and see what I think.

Latest hormone levels from me: fsh 10.7, amh 2.24 (up from 0.67!).

Here's hoping letrozole is cumulative from last time (as mr S claimed this morning).

Looking forward to catching up with you all.

Welcome back jaffajiffy. In what way does Mr S think letrozole is cumulative? With more/better follies?

Hi Brightside, I'm so sorry about your BFN. Its so heartbreaking isnt it. Its such a build up that for it not to happen is so devastating. I never heard back from the Agora and then had my referral changed to the esperance. That was my first visit. How did you find the Agora? Do you have more NHS rounds? Better luck next time, I hope. X x x

Jaffa Mr S said to me that letrozole was cumulative but not sure how

Thanks Carebear. All the very best to you at the Esperance. DP and I still have very mixed feelings about the Agora (possibly heightened by the BFN). We have one more NHS go with them so will use that. We've decided to limit ourselves to 3 goes - and if we do have to be third time lucky then it will be credit card in hand to ARGC ..... (although really hoping it doesn't get to that !!!)

Take good care and best of luck for your next cycle.

xx

hey Ladies... I've not been on here for a while so just skimming through. Ari so you tested positive for the same 2 infections as me?
DH and I have just finished our hardcore anti bitoics... we are now taking pro biotics on the advice of Zita West nurtitionalist so we get the good bacteria back. I also saw your link on 'just momies' site and can see the pattern.

I hope you are ok?

Is pebbles ok ?

Had a dream about us all last night. We were on a coach going somewhere.

Anyway... sorry not to name check ..there are a few new names on the thread I see.

I will pop to NK thread to say hi now.

Hello all, I've not been on here much recently either. Seem to have found myself posting on the NK thread too, rather than here. It's been a ridiculous week of mentalling for me as AF decided to keep me guessing for an extra 5 days. She's here now so I'm back to square one on my 5th SO cycle. Only 2 more left and then, who knows? Mr S seems to think that I have as much chance naturally as I do with IVF. We'll have to look into that more as and when we need to. In the meantime, OH will have another SA test. Something called a FISH test, which reading up about it sounds like something we should've had years ago! I really can't understand why the NHS didn't do this test after our 2 TS21 pregnancies. Maybe it's new.

I will also be starting Hydroxy on this cycle. Looking forward to coming off Pred. Although last time I took anti malaria pills I had to stop because they made me feel dreadful!

Buzzybee, are you around? How are you getting on with the Gonal F?

Pebbles is quiet. Hope all is ok?

kittens i'm still around, I'm finding the Gonal F ok, felt a bit weird at first, I've had 2 scans now this cycle, usually I ov around cd12 so had scan on cd10 only 12mm, so had another on cd14 and the follie is only 14mm so i'm having some extra gonal f for 2 days and should ov cd17/18. He said he'd give me a stronger dose next time and something to thicken my lining. Mr B needs to give another SA and we might consider IUI soon

A friend of mine had a telephone consultation with Dr Fisch from the Sher Institute in the US where he told her that the intralipids were important. Shehata said I could have them if I wanted