Harmony Test is available outside of London but it is a lot more expensive so it is worth looking to see if you'll save money by travelling there. Nearest place to me that I've been recommended is just outside of York but it is £600 without train fares. Going to London with my OH will cost us £380 WITH travel costs. That's from Manchester. Personally I won't go anywhere for it that I haven't been recommended anyway.
Fetal Medicine Centre puts the money back into research. It's the same clinician who developed the nuchal fold measurement test in the first place so definitely reputable. They're pushing for Harmony to be available ASAP on the NHS but to back it they'll need the positive research. I can't wait to be a part of it.
Those who aren't having the down's screening, just thought I'd add that I didn't with my first baby either as I was 23 at the time and suffering from anxiety (I was in a difficult job at the time and always at risk of harm) and the midwife talked me out of it because she thought it'd just make the anxiety worse. I didn't think I'd mind about DS but I hadn't researched it thoroughly at the time. Once I got the diagnosis at the 20 weeks scan of her heart defect (half of babies with DS have heart defects and require surgery of some description) they recommended amnio and that's when I got the diagnosis.
I wouldn't go back and have the screening and change things, but I do think it is probably harder to decide what to do once you have felt your baby moving around, seen it several times etc. Even her 16 week heartbeat sounded absolutely fine. I'm not saying you should change your minds but it is worth researching DS thoroughly because they don't tell you enough when you're pregnant (because there just isn't time to warn you about these things). A huge number of babies die before term or before they are 1 year old with DS, males will never have children (only 2 recorded fathers with DS), females have an extremely high miscarriage rate... early dementia, 1 in 100 will have leukemia, unknown severity of learning difficulties, gastrointestinal problems... for me there were too many things to put my baby through. She would definitely have needed open heart surgery if she'd have ever gotten strong enough for it.
The only reason I wouldn't go back and change whether I had the screening or not is because I got far enough for my OH to feel her kick (sadly after the diagnosis) and that was a very special moment to us.
Your whole life would change whatever you decided to do if your baby had DS, or any disorder for that matter. There isn't an easy option. My friend got 1 in 330 at her screening and they nearly talked her out of the amnio because she was 22. She insisted and she was the one and had her baby 4 days after I had my baby. 2/3 of babies with DS are conceived by younger mums (this is because younger mums have more babies in general, so older mums are still more likely to have babies with DS but they just have less babies in general).
On a final note, people think I didn't want my baby because I'm young and didn't want the lifestyle change. I'm a student social worker and passionate about disability rights. I know all the available support avenues. Nothing in this world would allow me to keep her knowing it was for my benefit rather than hers though. It hurts having to sign on the dotted line to end your baby's life. I never thought I would do it. I was Catholic and lost huge parts of my life in those two weeks. My baby and part of my identity. It wasn't worth keeping them and hating myself if she had died in pain though for the sake of being able to keep her a bit longer.