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Share your dilemmas and get honest opinions from other Mumsnetters.

To wonder if there will be any fall out from skinny jabs?

559 replies

TheLemonGuide · 20/04/2026 16:40

Everyone I know is now suddenly very slim. Okay, im exaggerating slightly, but genuinely, most of my friends who were previously overweight are all now slim thanks to skinny jabs. I am delighted for them! It seems unbelievable to think that a jab can cure this obesity crisis, but I am so pleased my friends and a couple of family members are able to live a healthier life thanks to this.

My only slight concern is, is this something that is going to be too good to be true? Do you think there will be any long term repercussions, or are we right to just celebrate this medication as a cure for something that so many have been battling for so long?

OP posts:
Yuja · Today 06:04

All medicines have side effects. WLIs won’t be any different - side effects will manifest in a small percentage.
I previously suffered severe anorexia. I no longer have this diagnosis but I do as an adult still have disordered eating and I am very thin. I have to be honest that the more I see people who aren’t even very overweight being able to get their hands on them easily, the more the idea appeals to me. I wouldn’t, but the social side effect of these for people like me is dangerous - the concept of something to stifle your hunger and make your attempts to starve yourself easier is attractive when you suffer from ED/disordered eating.

Just another perspective. I do know a couple of people on them whose lives have been transformed and don’t appear to be suffering side effects and I think that’s great for them.

pdjafcwtaoa65 · Today 07:30

IberianLynx · Today 05:49

A good friend of mine took the contraceptive injection for years and now has a brain tumour linked to this (I don’t believe that this has much publicity but is very real for a lot of women). There is bound to be side effects and risk with WLI, I agree that it will be interesting to see what these are and if they are serious in the future.

I am far, far more afraid of hormonal contraception than I am these drugs because they are so overlooked. We push young teen girls on them and I think they are hugely harmful, I don’t think we’ve properly explored at all the impact on anxiety and wider mental health when on these drugs. Plus more evidence coming out now about impact to health when you stop ovulation. But we’ve dismissed this for decades because a) we don’t care about women b) men want sex.

CautiousLurker2 · Today 07:31

icecreamflowers · Today 01:38

People, like my previously normal-weight friend with the lengthy history of bulimia, are just getting them off the internet somehow.

And my mother, who also had anorexia and bulimia, abused laxatives - she would go into every chemist within a 5mile radius several times a month to ensure she could take 70+ a day. They were a contributory factor in her death at 56yo, weight 7 stone at the time. They are a commonly abused over the counter medication that clinicians and the psychiatric community have been aware of since Karen Carpenter’s death. But no-one on here or at the Daily Fail is bewailing their existence and saying they should be banned or even just regulated, are they? I wonder why that is…

Craftycariad · Today 07:47

gamerchick · 20/04/2026 16:59

Well a lot of people at work have been on them a while and packets of rennies have started to show up on desks. So I'm wondering who's going to be the first to get booked in for gallbladder removal.

Not that I'd say that out loud. It's an interesting private experiment.

Having gallbladder issues is common when you lose a lot or weight, however you lose it . So yes it may happen but that isn't because of the jab.

CautiousLurker2 · Today 07:54

Craftycariad · Today 07:47

Having gallbladder issues is common when you lose a lot or weight, however you lose it . So yes it may happen but that isn't because of the jab.

Yes, and GPs who say they are seeing more gall bladder issues since WLI are doing so because more people are losing weight than previously. According to Google there has been a 20-30% increased in gall bladder issues in both the US and UK over the last 30 years, with 10-15% of people experiencing issues (with approx 70,000 cholecystectomies performed annually in the UK even as far back as 2019, before WLI were a thing).

When a handful GPs say they are seeing more of them since WJI they are mis-applying two largely unrelated facts and incorrectly inferring causation, when there is not even a correlation. They need to update their training in this area before giving patients their ill-informed opinions.

Being GP does not make you an expert unless you have actually chosen to specialise in this area and done the appropriate professional training.

Feelingworried26 · Today 08:22

OwlBeThere · Today 01:42

Fair. I didn’t express what I meant very well there. I just meant it’s no different to any medication in the respect that if you take it as prescribed then there is no more to worry about than any other medication. No one is sitting about angsting over the potential side effects of paracetamol. Because people accept that the risk when used correctly is outweighed by its effectiveness.

Yes its a judgement call each time you take a drug. But I think that the high numbers taking WLIs might possibly reveal more side effects.

measuringtaep · Today 08:24

icecreamflowers · Today 01:38

People, like my previously normal-weight friend with the lengthy history of bulimia, are just getting them off the internet somehow.

You know this is a problem with many people suffering illness and a huge array of prescription medications though?

Frequency · Today 09:50

I think the fallout from them will come mainly from the way they are being marketed, the way they are far too easily accessible, and the way they are being used irresponsibly by both the people who do not need them and those who do need them but want fast results.

I know in MNLand everyone who uses them does so responsibly, works out and eats well, and is the correct BMI to obtain them, but back in the real world the rest of us have eyes and know that's not the way they are being used by the majority.

Most people are losing weight far too quickly, which will have a lasting impact on their general health, muscle mass, and bone density. It's far too easy to get hold of them, even if you don't need them. They are not being prescribed with enough oversight because the people prescribing them are primarily profit-driven. They don't care about your health; they just want your money.

anon666 · Today 09:56

Yeah, there will be a flipside, but the question is whether that is as bad as the obesity crisis was.

It's natural to think "nothing can be achieved without a payback". Its how we think. But there are genuine examples of medical progress, like antibiotics. And this might be one. Time will tell.

Meanwhile, half the population who were grappling with a previously "unsolveable" health problem have had a solution.

I don't think the costs will outweigh the benefits

Witchonenowbob · Today 09:56

Tuesdayschild50 · Yesterday 20:07

People might look slimmer but they also look older due to loss of facial volume wrinkly skin loose skin on the body because its being lost too quickly .. id rather have a curvy body with no lose skin ... as always people just hammer the jabs .. don't change their eating habits still don't exercise .. so eventually will end up back the same way or skinny but wrinkly and loose.

Edited

You be curvy and overweight, but others want to be slim? Some exercise, change eating habits etc.

Just like any other diet!

You sound really unkind with your skinny and wrinkly comment, it’s like you want people to end up like this, so you can prove a point.

pdjafcwtaoa65 · Today 09:58

@Frequency that’s quite a statement to make with no evidence, the “majority” are using them wrong, how can you possibly know that? I also dispute your claim that people are losing weight too fast, most people I know on them have been on them for a long period and after the initial larger losses (common across all weight loss methods) the average weight loss is often around 1lb a week, that is not “too quickly”.

CautiousLurker2 · Today 09:59

Frequency · Today 09:50

I think the fallout from them will come mainly from the way they are being marketed, the way they are far too easily accessible, and the way they are being used irresponsibly by both the people who do not need them and those who do need them but want fast results.

I know in MNLand everyone who uses them does so responsibly, works out and eats well, and is the correct BMI to obtain them, but back in the real world the rest of us have eyes and know that's not the way they are being used by the majority.

Most people are losing weight far too quickly, which will have a lasting impact on their general health, muscle mass, and bone density. It's far too easy to get hold of them, even if you don't need them. They are not being prescribed with enough oversight because the people prescribing them are primarily profit-driven. They don't care about your health; they just want your money.

I do agree with some of what you say- there is no reason for people to be losing 6 stone in 6months on the higher doses. I took 15m to loose that amount at about 1lb a week, which was sensible. Largely on 10mg, carefully monitored by my provider, with monthly zoom appointments with a clinically trained professional (nurse). They asked for updates on blood tests for thyroid etc when I had them with my GP. That SHOULD be the protocol.

Binus · Today 10:14

pdjafcwtaoa65 · Today 09:58

@Frequency that’s quite a statement to make with no evidence, the “majority” are using them wrong, how can you possibly know that? I also dispute your claim that people are losing weight too fast, most people I know on them have been on them for a long period and after the initial larger losses (common across all weight loss methods) the average weight loss is often around 1lb a week, that is not “too quickly”.

Source- she made it up!

dh280125 · Today 10:21

Drugs like this have been used for decades to treat diabetes. There are a number of mild side effects that most people experience that fade over time, and a smaller number of serious side effects that few will experience and none of which are as serious as the negative effects of obesity when taken as a whole. You should certainly adjust your diet, and do resistance based exercise, as well as take the drugs. The main fall out will be a divided society between those who can afford the drugs, and will be healthier, and those who cannot. There is significant emerging evidence that GLP1 drugs are also beneficial for dementia, addiction and other issues, not just diabetes and obesity. I speak as someone who is significantly healthier having lost over 1/3 of my weight on "the jab."

susiedaisy1912 · Today 10:29

Why are people so worked up about what the possible consequences are of those taking the is medication. All the reasons mentioned so far are neither here nor there in the grand scheme of things. Obseity, smoking, alcohol, drugs, a diet heavy in Upf and fat along with a sedentary lifestyle are far far bigger issues for the NHS.

susiedaisy1912 · Today 10:31

dh280125 · Today 10:21

Drugs like this have been used for decades to treat diabetes. There are a number of mild side effects that most people experience that fade over time, and a smaller number of serious side effects that few will experience and none of which are as serious as the negative effects of obesity when taken as a whole. You should certainly adjust your diet, and do resistance based exercise, as well as take the drugs. The main fall out will be a divided society between those who can afford the drugs, and will be healthier, and those who cannot. There is significant emerging evidence that GLP1 drugs are also beneficial for dementia, addiction and other issues, not just diabetes and obesity. I speak as someone who is significantly healthier having lost over 1/3 of my weight on "the jab."

There are many trials going on worldwide to determine whether these drugs can help with addiction. Just think of how many lives might be transformed if in a few years addiction could be treated with a jab. It’s exciting stuff.

JayJayj · Today 11:31

OwlBeThere · Today 01:45

How are you taking half doses?

Really good. It has curbed my appetite but not having any other symptoms thankfully. When I took a normal dose I felt rather unwell. I am eating small portions but not silly small. Before this I could have 2 breakfasts and still feel hungry an hour later. I know people think it’s cheating but I just needed some help.
ha ha sorry I read how are you feeling!!!

I simply measure to 0.15 instead of 0.25

Mintchocs · Today 11:35

I'm really happy for anyone benefiting from them. I've always had a low body weight (mostly from always being v active I think as I'm just made that way). I think how lucky I am quite often that I don't struggle with food and weight. Not yet anyway, not menopausal yet!

Anyway, the only potential problems are likely to be bad bone loss in people who lose fast and don't eat protein/lift weights, and regaining the weight if you can't afford to keep injecting.

MyBrightPeer · Today 11:43

People are so desperate for jabs to go wrong out of I don’t know, jealousy? A sense that it’s “cheating”?. We treat other medical conditions medically, it is perfectly reasonable to treat obesity and excessive weight as such too.

Would you still be worried about “the fall out” if people on jabs lost all that weight without intervention?

Frequency · Today 11:46

No one is desperate for them to go wrong; they have genuine concerns about the long-term use for a variety of reasons. This idea that everyone is just jealous is bizarre. Anyone who has access to Google knows how to get hold of them at a lower body weight. If they were jealous they'd be doing that instead.

Washingupdone · Today 11:59

dh280125 · Today 10:21
There is significant emerging evidence that GLP1 drugs are also beneficial for dementia, addiction.
If this seems to be able to help a host of other additive problems, thinking of gambling, illegal drugs, alcohol, can only come too soon enough.

Pikachu150 · Today 12:20

Frequency · Today 11:46

No one is desperate for them to go wrong; they have genuine concerns about the long-term use for a variety of reasons. This idea that everyone is just jealous is bizarre. Anyone who has access to Google knows how to get hold of them at a lower body weight. If they were jealous they'd be doing that instead.

Maybe they already have a lower body weight, but they believe that they've worked hard to achieve it and don't like the fact that other people just seem to be doing it with medication. That's the way it comes across with some people on here.It just seems so unlikely that people are particularly concerned about long term effects the weight loss drugs when they don't seem concerned about many other drugs including those which have been around for much less time. The weight loss drugs have been around for about 20 years.. There seems to be another agenda.

SwingTheMonkey · Today 12:22

Frequency · Today 11:46

No one is desperate for them to go wrong; they have genuine concerns about the long-term use for a variety of reasons. This idea that everyone is just jealous is bizarre. Anyone who has access to Google knows how to get hold of them at a lower body weight. If they were jealous they'd be doing that instead.

Thats disingenuous. I’ve read enough WLI threads on here where posters have openly said they are ‘looking forward to’ the negative consequences of using WLI to show up. Actually looking forward to it. And these aren’t just overweight people but slim people who seem to think weight loss should be difficult as a punishment for being overweight in the first place.

Witchonenowbob · Today 12:22

Pikachu150 · Today 12:20

Maybe they already have a lower body weight, but they believe that they've worked hard to achieve it and don't like the fact that other people just seem to be doing it with medication. That's the way it comes across with some people on here.It just seems so unlikely that people are particularly concerned about long term effects the weight loss drugs when they don't seem concerned about many other drugs including those which have been around for much less time. The weight loss drugs have been around for about 20 years.. There seems to be another agenda.

Oh the long term effects of obesity, yet oh so concerned about the effects of losing weight.

teaandtoastwouldbenice · Today 12:30

Hopefully the repercussions will be a reduction in obesity related illness

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