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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

To think it will be revealed WLI cause physical aging

830 replies

Tuliptana · 02/03/2026 07:14

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

OP posts:
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18
SilenceInside · 04/03/2026 17:01

And some people who don't take WLI seem sort of religiously convinced of the fact people who do, look worse and ill, in turn.

I know I look better and healthier because I know what I looked like before and what I look like now, unsurprisingly. I also know that I am objectively healthier - I have had blood tests that confirm this, BP measurements, fitness measures, and so on. A decent-sized body of data confirming vast improvements in my objective health. Even if I looked like shit, I still would know that I am actually healthier and that my awful appearance was simply cosmetic. But you might see my poor haggard and sallow face, @Soontobesingles , and decide that I am unhealthy, but you would be wrong.

RobinEllacotStrike · 04/03/2026 17:06

Of course, many women are obsessed with "looks".

Maybe it is difficult for these people to realise not everyone thinks the same way, not every women prioritises "looks" over everything else in life, and many many women simply don't GAF about other peoples opinions on if they look "old" or not.

Soontobesingles · 04/03/2026 17:12

SilenceInside · 04/03/2026 17:01

And some people who don't take WLI seem sort of religiously convinced of the fact people who do, look worse and ill, in turn.

I know I look better and healthier because I know what I looked like before and what I look like now, unsurprisingly. I also know that I am objectively healthier - I have had blood tests that confirm this, BP measurements, fitness measures, and so on. A decent-sized body of data confirming vast improvements in my objective health. Even if I looked like shit, I still would know that I am actually healthier and that my awful appearance was simply cosmetic. But you might see my poor haggard and sallow face, @Soontobesingles , and decide that I am unhealthy, but you would be wrong.

the reason you seem defensive is that you seem to think the negative things I have observed in some other people who take mounjaro apply to you, despite the fact I don't know you and you say they don't. I've obviously got no idea about how the drug is impacting, you and hope you are well and experiencing the benefits.

I do know the friend I saw yesterday, a man as a it happens, is so thin at aged 50 (he brags about being she same weight he was at 25) that he has visible kind of skeletal cheekbones. When I first saw him about 6 months after he started on the drug I literally went to the bathroom and cried, because I was convinced he had arranged the meeting because he was about to tell me he had a terminal illness. That's how bad it is. He is yellow with skin hanging off him. He looks frail like a terminally ill person before they die. He is also delighted to have lost all this weight and believes he looks great. I obviously said I was a little concerned he had lost too much and he laughed it off. I have a cousin who is similarly looking very, very unwell as a result of the weightloss from these drugs. Perhaps I am wrong and you can look emaciated and still be healthy. I don't doubt that these are game-changing drugs if you need them and take them safely. I can also see with my own eyes that they are dangerous for people who take them only because they want to look thinner.

Soontobesingles · 04/03/2026 17:13

RobinEllacotStrike · 04/03/2026 17:06

Of course, many women are obsessed with "looks".

Maybe it is difficult for these people to realise not everyone thinks the same way, not every women prioritises "looks" over everything else in life, and many many women simply don't GAF about other peoples opinions on if they look "old" or not.

Edited

If you genuinely think that people are not taking these drugs to look 'better' you are insane.

Nanda66 · 04/03/2026 17:14

I’m religiously convinced that I look better and I feel healthier, because I do. I look great. I’m in my late 50s so sadly my face does look a bit older but the upside is that I feel confident, am loving buying and wearing clothes and feel healthier. That is all good. If you looked at me before you would never have said I was obese, just overweight, but I was technically obese. Fortunately I had no health conditions and don’t take any medication. Like many others I weighed up the risks of WLIs just as I would with any other medication. It’s been 100% worth it even though I’m normally quite risk averse and I’ve lost the weight slowly, steadily and sensibly. There are more people like me than you realise, lots of us are looking and feeling great.

Binus · 04/03/2026 17:14

I can also see with my own eyes that they are dangerous for people who take them only because they want to look thinner.

As previously pointed out, no you can't, because a person can be obese and still only doing it for cosmetic reasons.

It really is an important point. The risks and benefits of both obesity and WLIs exist regardless of what one feels about them and why a person takes a particular decision.

Soontobesingles · 04/03/2026 17:17

Binus · 04/03/2026 17:14

I can also see with my own eyes that they are dangerous for people who take them only because they want to look thinner.

As previously pointed out, no you can't, because a person can be obese and still only doing it for cosmetic reasons.

It really is an important point. The risks and benefits of both obesity and WLIs exist regardless of what one feels about them and why a person takes a particular decision.

if they are obese, then they need the drug for health reasons? So I don't really get the point you are making? If you need a medicine, you need it, and it's likely to improve your life...I have never disputed this.

Notsosweetcaroline · 04/03/2026 17:20

RobinEllacotStrike · 04/03/2026 17:06

Of course, many women are obsessed with "looks".

Maybe it is difficult for these people to realise not everyone thinks the same way, not every women prioritises "looks" over everything else in life, and many many women simply don't GAF about other peoples opinions on if they look "old" or not.

Edited

Yes, the issue is the people posting all the negative stuff are the ones obsessed with looks and can’t fathom anyone else might not be, for them it’s about their looks versus other women’s, it’s all about the fact we can be slim, and they can’t or they have to work harder in their view.

you won’t get them to agree, because for them, it is all about looks, that’s where the envy and discomfort, the resentment comes from. The fact it is for others about health, isn’t something they can accept, as they grapple with their own body image issues and compare themselves to other women.

Binus · 04/03/2026 17:22

Soontobesingles · 04/03/2026 17:17

if they are obese, then they need the drug for health reasons? So I don't really get the point you are making? If you need a medicine, you need it, and it's likely to improve your life...I have never disputed this.

It sounds like who you're actually talking about then is people who don't meet the prescription criteria for WLIs and fall into the group who are only taking them for cosmetic reasons. You ought to be clear about your terms. That's particularly important when you've talked about a friend who fits into this category and decided that they were unnecessary in her case, despite the fact that if she met the prescription criteria there is evidence that the benefit is greater than the risk.

SilenceInside · 04/03/2026 17:22

@Soontobesingles if I take it that you mean people like me, it’s because you have been unclear in who you are referring to and have been grouping legitimate use in with illegitimate use.

Maybe you should tell your male friend very clearly that you think he looks terminally ill, like he has end stage cancer. If he’s yellow, presumably that’s liver damage which would be an urgent issue if it’s not already. Sounds serious, and I hope he isn’t as unwell as you perceive him to be.

Notsosweetcaroline · 04/03/2026 17:22

Binus · 04/03/2026 17:14

I can also see with my own eyes that they are dangerous for people who take them only because they want to look thinner.

As previously pointed out, no you can't, because a person can be obese and still only doing it for cosmetic reasons.

It really is an important point. The risks and benefits of both obesity and WLIs exist regardless of what one feels about them and why a person takes a particular decision.

And so what if they do it for cosmetic reasons they are still obese. You aren’t in competition with them, they aren’t with you. If they are obese and want to do it for cosmetic reasons, good for them. It will always improve their health markers, their longevity and their mental health as they love their appearance .

good for them I say.

TorturedParentsDepartment · 04/03/2026 17:23

Nanda66 · 04/03/2026 16:28

But most people pay for Mounjaro. It doesn’t mean that you’re not eligible or shouldn’t be taking it if you pay for it. It’s legitimately prescribed by private pharmacies. I certainly pay for mine, my starting BMI was 33 and I have no health conditions so I knew I wouldn’t be eligible on the NHS. In fact I don’t know anyone who has been prescribed it by the NHS, everyone I know who is taking it is paying for it.

Just because people are paying for it doesn’t mean they’re not eligible. There are so many misconceptions around this drug.

I had a BMI of something like 54! I was nearly 25 stone - however because I only had some creaky joints and am otherwise in decent health - I won't qualify on the NHS for a very long time as they roll it out gradually - I didn't have the required number of co-morbid weight-caused health conditions.

I could:
a) carry on waiting until the criteria relaxed - getting fatter and iller
b) carry on waiting until I developed enough health conditions - I do not fancy fucking with diabetes having seen the damage that can do uncontrolled
c) get off my arse and finance it myself

I won't apologise for choosing option c, clearly within the guidelines for people for whom the drug is indicated but taking the opportunity to pay for it privately - thus saving the NHS money in terms of initial cost of the drug plus the cost of not having to treat the obesity related health conditions I don't develop as the result of getting 10 points and counting off my BMI score. Plus the costs they're not going to incur as a result of me getting my mobility and activity levels up to a level I'm at the gym most days as a result of dropping enough weight to be able to do this.

The NHS has to juggle cost-benefit for anything it approves - it's not the arbiter of absolute prescription licensing - there are drugs and treatments it doesn't fund because the men in suits with calculators view the costs as not being justified by the benefits - we have to make the case for every communication aid iPad my service funds - we don't hand them out to everyone with communication problems... doesn't negate someone wanting to help themselves or their family and sourcing their own device or software if they don't quite meet our criteria. Same with mounjaro, wegovy and any other drugs in the pipeline.

Yes there are morons out there using it as the only way they're planning on losing weight, there are people trying to "cheat" (it's been tightened up a LOT from when it was launched) and there are idiots jabbing themselves with fuck knows what they bought from the hairdresser round the corner... but there are also a hell of a lot of people out there like I was - at the point where a body had become so limiting you were trapped by your size, who needed to calm the food noise (if you don't experience this you won't ever fully get the impact these GLP1 agonists can have where other stuff doesn't) and get enough weight dropped to be able to make longer term changes like walking and going to the gym - because moving a 25 stone body around is bloody HARD (not to mention the abuse you get).

Soontobesingles · 04/03/2026 17:28

Notsosweetcaroline · 04/03/2026 17:22

And so what if they do it for cosmetic reasons they are still obese. You aren’t in competition with them, they aren’t with you. If they are obese and want to do it for cosmetic reasons, good for them. It will always improve their health markers, their longevity and their mental health as they love their appearance .

good for them I say.

it's weird you think I see it as competition. In what way would my being concerned about my friends and family mean I am in competition with them? I'm not. I am 42 years old, married and happy. I see it as a public health risk. My cousin who looks very unwell has always been better looking than me in honesty, and never overweight, and I've never felt competitive about that. I am worried about her.

Notsosweetcaroline · 04/03/2026 17:29

Soontobesingles · 04/03/2026 17:28

it's weird you think I see it as competition. In what way would my being concerned about my friends and family mean I am in competition with them? I'm not. I am 42 years old, married and happy. I see it as a public health risk. My cousin who looks very unwell has always been better looking than me in honesty, and never overweight, and I've never felt competitive about that. I am worried about her.

A public health risk, 😂😂😂 bet you don’t react the same about other meds. Just the ones where women become slim.

a risk to your mental health maybe.

Soontobesingles · 04/03/2026 17:30

Binus · 04/03/2026 17:22

It sounds like who you're actually talking about then is people who don't meet the prescription criteria for WLIs and fall into the group who are only taking them for cosmetic reasons. You ought to be clear about your terms. That's particularly important when you've talked about a friend who fits into this category and decided that they were unnecessary in her case, despite the fact that if she met the prescription criteria there is evidence that the benefit is greater than the risk.

she met the prescription criteria because she didn't tell the only prescriber she was postpartum and breastfeeding. I mean, I was pretty clear about my terms in my first post - as it started with the point that they are a game-changing drug for anyone with a medical need of them.

Binus · 04/03/2026 17:32

Soontobesingles · 04/03/2026 17:30

she met the prescription criteria because she didn't tell the only prescriber she was postpartum and breastfeeding. I mean, I was pretty clear about my terms in my first post - as it started with the point that they are a game-changing drug for anyone with a medical need of them.

So she didn't meet the prescription criteria then. And no, you have not been clear about your terms. We've had vague descriptions based on your subjective perceptions, and even just in your first post you were talking about looking and seeming.

AstoriaQueen · 04/03/2026 17:36

Im on WLI and just had cosmetic surgery. I had multiple blood and other tests scans etc etc before and all were absolutely perfect. I think you just sound jealous 😏

Soontobesingles · 04/03/2026 17:37

Notsosweetcaroline · 04/03/2026 17:29

A public health risk, 😂😂😂 bet you don’t react the same about other meds. Just the ones where women become slim.

a risk to your mental health maybe.

React how? If I see anyone who looks ill because they are taking meds they have bought off an online prescriber, I'd be worried. I (genuinely) wonder if the defensiveness in you and others on the WLs is because those who have spent their life being jealous of thin women cannot conceive that some of us just don't really see other women (or men) in terms of competition in that way?

I also have actually done quite extensive campaigning through work about the risks of hormonal contraceptives, so I do think that women's health is important. A drug aimed at getting women to look conventionally more attractive (i.e slimmer), that can be sold for massive profit to the drug companies obviously has no risk whatsoever of being proven to be dangerous? You'd have to be ignorant of the history of women's health to think that.

Binus · 04/03/2026 17:38

SilenceInside · 04/03/2026 17:22

@Soontobesingles if I take it that you mean people like me, it’s because you have been unclear in who you are referring to and have been grouping legitimate use in with illegitimate use.

Maybe you should tell your male friend very clearly that you think he looks terminally ill, like he has end stage cancer. If he’s yellow, presumably that’s liver damage which would be an urgent issue if it’s not already. Sounds serious, and I hope he isn’t as unwell as you perceive him to be.

Yes, if someone is yellow that sounds like potential for a rather significant health concern! I do hope he's spoken to a doctor.

Soontobesingles · 04/03/2026 17:39

AstoriaQueen · 04/03/2026 17:36

Im on WLI and just had cosmetic surgery. I had multiple blood and other tests scans etc etc before and all were absolutely perfect. I think you just sound jealous 😏

And I think you sound like someone who has spent much of their life desperately insecure about how they look, and now, having accessed procedures to rectify that self-esteem issue, are desperately hoping those of us who haven't struggled in that way will envy you. It's genuinely sad, and I wish you peace.

likelysuspect · 04/03/2026 17:40

SilenceInside · 04/03/2026 17:22

@Soontobesingles if I take it that you mean people like me, it’s because you have been unclear in who you are referring to and have been grouping legitimate use in with illegitimate use.

Maybe you should tell your male friend very clearly that you think he looks terminally ill, like he has end stage cancer. If he’s yellow, presumably that’s liver damage which would be an urgent issue if it’s not already. Sounds serious, and I hope he isn’t as unwell as you perceive him to be.

He probably doesnt look anything like this.

I had similar, people saying I was too thin, 'skinny', dont lose any more

Im a normal weight!

Soontobesingles · 04/03/2026 17:41

SilenceInside · 04/03/2026 17:22

@Soontobesingles if I take it that you mean people like me, it’s because you have been unclear in who you are referring to and have been grouping legitimate use in with illegitimate use.

Maybe you should tell your male friend very clearly that you think he looks terminally ill, like he has end stage cancer. If he’s yellow, presumably that’s liver damage which would be an urgent issue if it’s not already. Sounds serious, and I hope he isn’t as unwell as you perceive him to be.

I have told him he looks ill. He doesn't agree and won't see a dr. Tbh it seems like an ED to me, brought on by the drugs and the high of losing weight. There isn't much I can do really other than continue to gently be there for him.

RobinEllacotStrike · 04/03/2026 17:42

Soontobesingles · 04/03/2026 17:13

If you genuinely think that people are not taking these drugs to look 'better' you are insane.

You seem quite determined to misrepresent everyone on this thread.

You seem so very concerned about so many people around you, when really you'd be better off minding your own beeswax.

SilenceInside · 04/03/2026 17:42

Just a point, WLI are aimed at treating obesity, they are not aimed at making women more conventionally attractive. I don’t think that was one of the clinical trial outcomes that was studied.

Soontobesingles · 04/03/2026 17:45

RobinEllacotStrike · 04/03/2026 17:42

You seem quite determined to misrepresent everyone on this thread.

You seem so very concerned about so many people around you, when really you'd be better off minding your own beeswax.

people I care about and am close to are my business? The social norms around women's bodies that we are establishing and that my dds will grow up in are my business. Honestly the defensive lunacy on this thread is mind boggling. I might be a little jealous of I don't know, the looks of someone like Jennifer Lawrence in her prime. Literally no one with a normal mindset is jealous of a 50 year old who has been obese their whole adult life, lost a few pounds and had a budget facelift!

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