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Share your dilemmas and get honest opinions from other Mumsnetters.

To think it will be revealed WLI cause physical aging

830 replies

Tuliptana · 02/03/2026 07:14

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

OP posts:
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18
Binus · 04/03/2026 10:35

Forestgreenblue · 04/03/2026 09:13

I think it’s great that a lot of people who were significantly overweight and unable to lose weight before have managed on the jab. Loose skin is purely from rapid weight loss and loss of collagen.

However the weight loss jab ultimately doesn’t magically solve the reason they were overweight in the first place and if they don’t work on their own eating habits and healthy habits I would imagine stopping the jab would cause weight regain. It is also not without its risks.

Personally we have had 2 people in our family who have been on them - one ended up in hospital and had her gall bladder removed - now will have life long issues as a result - and one hid her symptoms of dreadful gastro issues and significant pain for months before stopping, though she was happy with the results of her weight loss, she actually looked really poorly a lot of the time and had the reported ‘ozempic face’. She was actually grey at one point. We were terribly worried about her as she wasn’t actually particularly overweight to begin with. She’s regained most of her weight though since stopping.

Long term I would be concerned about premature loss of bone density, particularly where the weight loss jab is being used by people who don’t medically qualify for it OR are using it when they are already underweight - Kelly Obsourne for example. In females this is something we will naturally decline with in age so early progression is a huge concern.

Id imagine with the majority of people who are getting their jabs from unregulated suppliers that their bone density isn’t being checked or tracked in any way.

Whilst people say, quite rightly, it’s a medication that has been utilised by diabetics for years so their assumption is that it’s completely safe - well an diabetics other option of not using it is frankly death. The jabs are a medication with risks associated to it, no matter which way you look at it.

Actually, the weight loss jab does very much solve the reason the person was overweight in the first place for many of us. That is, eating more than we burned off. Which isn't something that needs pathologising or can be cured, because it's a normal human behaviour.

Stopping the jab does usually lead to weight regain. As does traditional dieting. There's only one thing shown to successfully address existing obesity, and that's sustained WLI use. This obviously comes with risks, but so does being obese. Being obese and losing weight are both risks for gallbladder problems!

Lastly, I dont think 'not terribly overweight' is a very helpful description. People can be clearly obese, with all the risks that entails, and not be perceived as such by those around them.

likelysuspect · 04/03/2026 10:46

Binus · 04/03/2026 10:35

Actually, the weight loss jab does very much solve the reason the person was overweight in the first place for many of us. That is, eating more than we burned off. Which isn't something that needs pathologising or can be cured, because it's a normal human behaviour.

Stopping the jab does usually lead to weight regain. As does traditional dieting. There's only one thing shown to successfully address existing obesity, and that's sustained WLI use. This obviously comes with risks, but so does being obese. Being obese and losing weight are both risks for gallbladder problems!

Lastly, I dont think 'not terribly overweight' is a very helpful description. People can be clearly obese, with all the risks that entails, and not be perceived as such by those around them.

A friend of mine falls into the obese category, she is simply a stone more than me and Im a few lbs into the overweight category. Its as small as that, or as big as that however people want to see it

And absolutely the WLI 'cures' the reason for being overweight, which is overeating. We are designed to seek out high calorie foods as a species, its why we are still here, our bodies are designed to survive, like any animal. You dont see cats, dogs, bears, tigers picking away at nibbles, they eat high calorie dense food, they seek it out. They'll eat too much of it given the chance.

Thread after thread you get the pearl clutchers and po faced self righteous going on about 'deep seated issues' and 'therapy'. Most people become overweight through habit, ease of consumption, society and culture. The UK (or US/Australia) doesnt have any more 'deep seated' issues around food than other countries which have less obesity, what we have is a food culture that leads to overeating and plentiful opportunity. Simple as that.

Binus · 04/03/2026 10:52

likelysuspect · 04/03/2026 10:46

A friend of mine falls into the obese category, she is simply a stone more than me and Im a few lbs into the overweight category. Its as small as that, or as big as that however people want to see it

And absolutely the WLI 'cures' the reason for being overweight, which is overeating. We are designed to seek out high calorie foods as a species, its why we are still here, our bodies are designed to survive, like any animal. You dont see cats, dogs, bears, tigers picking away at nibbles, they eat high calorie dense food, they seek it out. They'll eat too much of it given the chance.

Thread after thread you get the pearl clutchers and po faced self righteous going on about 'deep seated issues' and 'therapy'. Most people become overweight through habit, ease of consumption, society and culture. The UK (or US/Australia) doesnt have any more 'deep seated' issues around food than other countries which have less obesity, what we have is a food culture that leads to overeating and plentiful opportunity. Simple as that.

And honestly, obesity is on the rise in nearly all developed countries. Even Japan. The only one that's managed to curb it recently is the US.

There aren't actually any examples of human societies that didn't hadn't develop an obesity problem once they had enough resources to provide the whole population with more calories than they need and also didn't have loads of the population on appetite suppressant drugs. It just happens sooner in some than others.

HeadDeskHeadDesk · 04/03/2026 10:58

Stopping the jab does usually lead to weight regain. As does traditional dieting. There's only one thing shown to successfully address existing obesity, and that's sustained WLI use. This obviously comes with risks, but so does being obese. Being obese and losing weight are both risks for gallbladder problems!

Agree. HRT raises the risk of breast cancer but most of us are prepared to take that risk on the chin given that our lives can be immeasurably improved by HRT. Statins are not without risk or side effects. Neither is chemotherapy. Sometimes the chemo will kill us before the cancer does. Every drug given to solve one issue carries a heightened risk of something else. Name me one that doesn't. It's a trade off. Always has been, always will be.

Exercising vigorously and taking part in sports heightens the risk of breaking bones, having accidents, needing joint replacements, rotator cuff problems, sometimes arthritis, reptitive strain injury, or simply dropping dead of a heart attack because in spite of appearing ostensibly fit and healthy, the extreme exersion highlighted a heart defect you didn't know you had, and might never have really troubled you if only you hadn't run that marathon.

But people are encouraged to do exercise and play sport because it's good for you in all sorts of ways, social, mental and physical that are deemed to outweigh those risks.

KimberleyClark · 04/03/2026 11:39

Re exercise, it’s known that the health benefits of moderate exercise over no exercise are far greater than the benefits of intense exercise over moderate exercise.

Notsosweetcaroline · 04/03/2026 12:21

Well I’ve been on nearly two years, maintaning for the last year on a low dose, all my blood test results now very healthy, it’s night and day compared to two years ago where I was an event waiting to happen . I look better, I feel better, I’m healthier, and without a doubt, I look younger. Mentally I am in a much better place, as feeling exhausted and not liking your appearance takes it’s toll.

so I shall keep on keeping on.those who are all covered in concern, i suspect you don’t need to worry as you can’t get them anyway, and that’s the real issue for you, for those of us lucky enough that we can get them. We are fully educated and will continue to make our own decisions, supported by our prescribers or GPs.

oh and I had no side effects either. Some mild nausea when I moved up to 5mg, not repeated, since. No consitpation, no sulphur burps, no nothing. Just improved health markers across the board.

but those pretending concern as you’re resentful and jealous as you can’t get them, if it’s cost it will come down, if it’s weight, then yup you need to keep struggling to maintain, sometimes life just isn’t fair.

Calliopespa · 04/03/2026 12:44

SherbetDipDap · 04/03/2026 10:19

God fat women can’t win, can they?

If they’re fat, they’re disgusting and unhealthy.

If they loose weight they’re haggard, old crones who have ‘cheated’ to loose weight.

A lot of thin women have a massive superiority complex.

A lot of women who were always thin are haggard and gaunt.

I just think whoever she was put it well when she said that after a certain age, it's a "choice between your bum and your face." That's the "bottom" line.

And I think we should just be a little bit judgmental of both sides of that coin. People tend to pick a side and say "well I'd rather be haggard than FAT" or vice versa.

Why not all just be a bit gentler and accept aging is hard. Peri can pre-dispose women to weight gain without them needing to be piggish gluttons, and it is hard not to look wrinkly if you keep to BMI levels that you had as a 16 year. A thin figure on a 61 year just doesn't look as lovely as on a 16 year old. That's life.

I mean if this were medieval times most posters on these threads would be dead so anyone over 40 is doing pretty well in that context.

To me it's all about a little bit less judgment and a bit more acceptance. Fat isn't "disgusting" anymore than wrinkling is "ugly"; they are less than ideal ramifications of getting older and I don't see why one has to be seen as morally inferior.

TheIceBear · 04/03/2026 12:48

Kellie Osborne does look very different and it’s quite worrying . But I know loads of people (colleagues etc ) who have lost weight recently who I suspect were using the injections and none of them look like that at all. I mean , that’s extreme really. I think having a bit of weight on can make some people look younger but being very overweight or obese ages people in my opinion.

Notsosweetcaroline · 04/03/2026 12:48

Calliopespa · 04/03/2026 12:44

A lot of women who were always thin are haggard and gaunt.

I just think whoever she was put it well when she said that after a certain age, it's a "choice between your bum and your face." That's the "bottom" line.

And I think we should just be a little bit judgmental of both sides of that coin. People tend to pick a side and say "well I'd rather be haggard than FAT" or vice versa.

Why not all just be a bit gentler and accept aging is hard. Peri can pre-dispose women to weight gain without them needing to be piggish gluttons, and it is hard not to look wrinkly if you keep to BMI levels that you had as a 16 year. A thin figure on a 61 year just doesn't look as lovely as on a 16 year old. That's life.

I mean if this were medieval times most posters on these threads would be dead so anyone over 40 is doing pretty well in that context.

To me it's all about a little bit less judgment and a bit more acceptance. Fat isn't "disgusting" anymore than wrinkling is "ugly"; they are less than ideal ramifications of getting older and I don't see why one has to be seen as morally inferior.

Miaow, you ask for acceptance but start off saying a lot of thin women are haggard and guant. Good grief, what an awful jealous thing to write.

Notsosweetcaroline · 04/03/2026 12:51

If feels like the new stick to beat peiple with,

like we tried long term effects, safety, side effects, it’s been in use so long and proven so safe we can’t use that any more so let’s go tell them they look older lol.

imaginw being so jealous you do that. Even in front of all the evidence otherwise, it’s utterly cringeworthy,

Calliopespa · 04/03/2026 12:57

Notsosweetcaroline · 04/03/2026 12:48

Miaow, you ask for acceptance but start off saying a lot of thin women are haggard and guant. Good grief, what an awful jealous thing to write.

Edited

Well I've always been quite thin, so there you go. No jealousy there.

The truth is older women don't look like they did when they were young. That is my point. It isn't necessarily because they have been overweight first. I am just trying to say it's lose-lose in every direction if you take a judgemental view.

There is just too much mud-slinging across the sides of the fence on these threads and all it really does is entrench women's lack of self-acceptance.

No-one is allowed to say anything about the possibility of the drugs having side effects, others won't accept people can look gaunt from age not drugs.

All these things can be true and I think it's about time we started building a vision for older women that wasn't so tied to how they look. There is way too much unhealthy pressure.

ETA the truth is the decisions are hard. personally I think where obesity is genuinely causing health problems, the drugs seem sensible. But an overly zealous approach to what is an untenable weight means people who don't need to take the possible risks are going to start taking them. That is why I think the suppression of any discussion of possible risk is dangerous.

Calliopespa · 04/03/2026 13:04

Notsosweetcaroline · 04/03/2026 12:21

Well I’ve been on nearly two years, maintaning for the last year on a low dose, all my blood test results now very healthy, it’s night and day compared to two years ago where I was an event waiting to happen . I look better, I feel better, I’m healthier, and without a doubt, I look younger. Mentally I am in a much better place, as feeling exhausted and not liking your appearance takes it’s toll.

so I shall keep on keeping on.those who are all covered in concern, i suspect you don’t need to worry as you can’t get them anyway, and that’s the real issue for you, for those of us lucky enough that we can get them. We are fully educated and will continue to make our own decisions, supported by our prescribers or GPs.

oh and I had no side effects either. Some mild nausea when I moved up to 5mg, not repeated, since. No consitpation, no sulphur burps, no nothing. Just improved health markers across the board.

but those pretending concern as you’re resentful and jealous as you can’t get them, if it’s cost it will come down, if it’s weight, then yup you need to keep struggling to maintain, sometimes life just isn’t fair.

The pictures posted on this thread are really positive examples of exactly what you are describing.

Shinyhappyapple · 04/03/2026 13:09

Binus · 02/03/2026 08:15

Well the first thing to remember is that dress size isn't a remotely scientific measurement. Presumably you don't think M and S joggers and Primark skinny jeans are going to be exactly the same, even if they both say size 12. Lots of women are indeed 5 foot tall, but as someone who's 5 foot 2, I can assure you I did indeed have some size 12 trousers before starting WLIs and having a 31 BMI.

Also you said earlier they were barely even overweight, which means low end of overweight BMI, perhaps 26. But now it's 24. 2 BMI points is actually quite a big difference!

I imagine you have good muscle tone , that makes a difference comparing weight to dress size. I’m 5’3”, generally wear a 16 but in some trousers I’m an 18 to accommodate my waist. I have BMI of under 28. My muscle tone is very poor.

BIossomtoes · 04/03/2026 13:22

Shinyhappyapple · 04/03/2026 13:09

I imagine you have good muscle tone , that makes a difference comparing weight to dress size. I’m 5’3”, generally wear a 16 but in some trousers I’m an 18 to accommodate my waist. I have BMI of under 28. My muscle tone is very poor.

Dress size is a ridiculous metric. The labels in my wardrobe range from 10 to 16. All those garments fit me. I believe BMI has been discredited too, not only because it fails to account for the higher weight of muscle, but because it doesn’t take age, ethnicity or anything else into account. It’s a very blunt instrument.

EnterQueene · 04/03/2026 13:24

Fat isn't "disgusting" anymore than wrinkling is "ugly"; they are less than ideal ramifications of getting older and I don't see why one has to be seen as morally inferior.

It is nothing to do with fat being 'morally inferior' what nonsense. Being fat is bad for your health. Wrinkles are not linked to increased risk of health conditions and disease as you age. If you value yourself, you will choose to be thin and wrinkled every time.

Notsosweetcaroline · 04/03/2026 13:26

BIossomtoes · 04/03/2026 13:22

Dress size is a ridiculous metric. The labels in my wardrobe range from 10 to 16. All those garments fit me. I believe BMI has been discredited too, not only because it fails to account for the higher weight of muscle, but because it doesn’t take age, ethnicity or anything else into account. It’s a very blunt instrument.

People always say this, but I’ve never experienced it. When I was a 16 I couldn’t get into a 10 and at a 10 an 16 always drowned me. Maybe it’s not the brands I buy from, but as much as I think most of us straddle two dress sizes, ie 8- 10, 10- 12, a 10 - 16 is outwith my experience.

SilenceInside · 04/03/2026 13:32

BMI is not discredited. It has always been a simple tool that indicates obesity rather than diagnoses it. It is accurate for a very large percentage of people, in that if BMI indicates that you are obese, measurements of your actual body fat will usually also show that you are obese, with a few exceptions. Eg athletes with a lot of muscle mass.

The NHS BMI calculator does take ethnicity into account.

Calliopespa · 04/03/2026 13:55

EnterQueene · 04/03/2026 13:24

Fat isn't "disgusting" anymore than wrinkling is "ugly"; they are less than ideal ramifications of getting older and I don't see why one has to be seen as morally inferior.

It is nothing to do with fat being 'morally inferior' what nonsense. Being fat is bad for your health. Wrinkles are not linked to increased risk of health conditions and disease as you age. If you value yourself, you will choose to be thin and wrinkled every time.

It is nothing to do with fat being 'morally inferior' what nonsense

Plenty of people treat obesity as inferior - just have a good search through these boards - and one of the things people feel criticised for over the WLI is a sense that people are implying they have somehow cheated. There ARE complicated issues of moral condemnation in it all.

In reality people are mostly just doing their best.

RobinEllacotStrike · 04/03/2026 14:07

I've lost 52 kilos on WLI - over 18 months.
BMI dropped from 41 to 24.

I do have wrinkly skin on my body but I can live with that.

I do have more & deeper wrinkles on my face & I do think I look older for it, but everyone tells me I now look 10 years younger.

Whatever - I'm really not bothered, I have no interest in the male gaze and I am feeling & (I think) looking pretty fantastic. I'm lighter, stronger, fitter and probably healthier thatn I have been for 40 odd years.

Personally I would never get fillers/botox etc - they hold no appeal for me. We get wrinkles as we age. Its really silly to get all worried about it.

TheNinkyNonkyIsATardis · 04/03/2026 14:08

SilenceInside · 04/03/2026 13:32

BMI is not discredited. It has always been a simple tool that indicates obesity rather than diagnoses it. It is accurate for a very large percentage of people, in that if BMI indicates that you are obese, measurements of your actual body fat will usually also show that you are obese, with a few exceptions. Eg athletes with a lot of muscle mass.

The NHS BMI calculator does take ethnicity into account.

I'm a combination of obese BMI, an athletic amount of muscle and a tall, broad frame. My shoulders are 2" wider than the highest average range for women, for example.

I wear a high BMI well - I think 20-27 is a more representative range of health for me.

I think a more holistic approach to health measures would benefit people more - resting heart rate, waist to height etc.

A size 6 WOULD look skeletal on me - I start to have pronounced collarbones etc at about 16st. Everyone would benefit from being more in tune with their health measures.

Mrsredlipstick · 04/03/2026 14:11

Forestgreenblue · 04/03/2026 09:53

They showed up 2 years prior though ?

I believe if they are unsymptomatic and at a size where they can possibly pass naturally then they are left in situ - however as you said you ended up being blue lighted to hospital and I am presuming in pain (so now symptomatic after weeks of using the jabs) leading to you having your gall bladder removed. I’d hardly say this is a good result of taking the jab.

On a further note gall bladder removal surgery is massively increased in the NHS at the moment because of the suspected link of the jab - which is reported and being reviewed on.

15% increase in gallbladder removal apparently.
Mine were caused by cheese apparently. I used to love cheese and wine.

My comment re a result was I had an undiscovered tumour which would have killed me.

FurForksSake · 04/03/2026 14:13

@Mrsredlipstick you are so lucky they found that. I know someone else who took mj (god knows how) it flared up their very long standing gallstones (previously refused to go ahead with surgery) and then discovered they had a tumour due to the flare caused by the mj. Sadly they are very much going to die from it. Biliary cancers are very, very often found too late and are inoperable. Thank goodness they found yours.

Mrsredlipstick · 04/03/2026 14:24

@FurForksSake it was a different type of tumor. It was showing on a second scan.

They couldn't take my gallbladder until they did the major surgery.

I'm now into my seven stone reduction but I wasn't allowed to diet until I finished my chemo drug.
I'm tall and tbh I'm really happy at a 14-16 ( having been a 24) I'm 60 and I'm not looking for a new Mr Lipstick!

likelysuspect · 04/03/2026 14:49

Seems to be a surprise to some people that collar bones are meant to be on show. Was a surprise to me anyway when I saw mine, never even knew they were there!!!

BIossomtoes · 04/03/2026 15:04

Notsosweetcaroline · 04/03/2026 13:26

People always say this, but I’ve never experienced it. When I was a 16 I couldn’t get into a 10 and at a 10 an 16 always drowned me. Maybe it’s not the brands I buy from, but as much as I think most of us straddle two dress sizes, ie 8- 10, 10- 12, a 10 - 16 is outwith my experience.

Well it’s most definitely within mine. I take exception to being called a liar because it doesn’t fit your narrative or your experience. Vanity sizing is also a factor - a 1980s size 10 was a very different proposition, it’s now labelled 8 or in some cases 6. When I was young size 6 didn’t exist.

Anyway, all of this is missing the point which is that dress size is a very unreliable metric for weight and size.