To think it will be revealed WLI cause physical aging

[Tuliptana]

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

This thread is a cesspit of medical misinformation with a lump of ableism "rather be fat than blind" and a soupçon of ageism
Imagine looking old and haggard what a terrible thing to happen, imagine how bad it would be to look old
I I mean it's a useful tool to see which posters possess utterly odious beliefs and I suspect the OP has sloped off having got exactly what they wanted from this thread

Certainly not all chronic conditions, but obesity is widespread. Why are we medicating millions of people with strong drugs, the long-term effects of which aren’t fully understood, when ultra processed food and the unethical practices of the food industry are at the root of the modern obesity epidemic?

Obesity is one of the main causes of cancer though were you not aware?

@LimeGoose people are choosing to use WLI because they cannot afford to wait for the pace of societal change to remove things like UPFs and so on, if that's even achievable. I was morbidly obese, and my health was being affected - I could not have waited for 10, 20 plus years for society to change and for that to have some effect on my weight and health. Isn't that pretty obvious?

I don’t see any of these jaundiced, hiv suffering, wrinkled crones around. I see people who were huffing and puffing walking round school a year ago now springing about confidently in fancy new wardrobes. Is there a word for the opposite of rose-tinted glasses?

Do you think peoples obesity will be cured by not buying a packet of ham?

I have a friend with significant health conditions related to obesity. GP wants them to take one of the jabs. They won't because of the ozempic face narrative that is doing the rounds. That and they worry they will be on it for life which I don't understand as they are on other meds to deal with their condition and will be for life.

I didn't try and persuade them as I appreciate there may be risks but then again there are risks with all sorts of meds.

I know one person who took it to lose weight and they are a powerful advert for it and no issues with severe weight loss in face.

It's because the claim you make here about what's at the root of the modern obesity epidemic is unevidenced. It's a guess. There isn't actually a single example of a human society that hasn't started to get an obesity problem once they all had enough to eat and most of them weren't smoking. Even Japan is starting, granted from a very low base.

In contrast, the science surrounding the dangers of obesity is well developed. So we choose the thing that we know works and also has the benefit of being a change that's easier to affect.

Yep. I started taking Mounjaro after 10+ years of battling anxiety and anxiety-related weight gain. My risk of a specific condition that occurs in my family was heavily increased by my obesity. Having been obese at all I am still at a higher risk but nowhere near as high. I don't fear this happening to anywhere near the same degree. Mounjaro mimics a natural process in the body and corrects a misfire. I couldn't recreate that with wishful thinking or long, concerned posts on mumsnet unfortunately.

Yes, I understand that. But maybe we could think about a the potential for a generation of people who are fully reliant on the pharmaceutical industry, which doesn’t care about them in the slightest, and have no idea how to manage their own weight and health without powerful medication. WLIs have a profound physiological impact (good and bad) and we shouldn’t pretend otherwise.

You're clearly not thinking about how people who are already obese are liable to be reliant on the pharmaceutical industry whatever they do, though. And the understanding that nothing is proven to address obesity on a societal level other than sustained WLI use is not something that can be glossed over. It does have to be the starting point, even if you want to argue that there are other ways to prevent people from becoming obese in the first place.

Do you think that about people on all medications for chronic conditions, or is it just obesity medications you have a problem with?

The latest science on obesity shows that it is much more complex than we used to believe, with genetics and hormones playing a significant role. It's not just a matter of eating right and moving more for people who are struggling with obesity. Many of them will only ever be able to lose and maintain a healthy weight with medication.

I'm lucky that I've never been overweight, but I really cannot understand the mentality of some of the people on this thread.

I don’t need the manufacturers to care for me, I have people in my life who do that, I no more need them to care for me than I do Ocado.

I agree the injections have a profound effect, if they didn’t we would not see threads like this, I don’t agree it is anything other than good though, but I’m happy to look at evidence otherwise if you have any. I do understand the very rare side effects, like I do for nurofen or any other drug I might take.

but I also understand the much bigger positive effects, from reduced cancers on.

the bottom line is no matter how resentful or envious people are, we will not stop taking them, we have educated ourselves, see the benefits in terms of our health and are loving it.

so it’s ok for you not to take it, it’s ok in my book for you not to be able to get it given your fears, you can continue as is. No one cares bar you.

A common side effect of gastric weight loss surgery is that the body can't absorb enough nutrients, so I wouldn't be surprised if Kelly has some nutritional deficiencies that are contributing to the way that she looks.

There are some people out there who are praising the way she looks, and I think that's a horrific way to go. Whatever combination of things is causing it, she does not look healthy.

Kelly has said she is mentally struggling right now, and is struggling to eat due to it. Let’s all believe hee shall we, rather than attack how she looks, accuse her of lying about not taking the injections now or lying about how much she eats and she’s a secret deficiency. Let’s just. Shall we.

This is the type of language I would expect from someone in a cult. I’m not anti WLIs. I think they’re probably the right choice for some people, but they are potent systemic drug and IMO shouldn’t be in widespread use. They aren’t equivalent to nurofen.

One of the best lines I’ve ever read on here in the past is useful for this situation - there are no wrinkles on a balloon 😂

As you mention they shouldn't be in widespread use but are ok with them in some cases, could you give us an idea of what you think the population frequency should be, and the criteria to access? Presumably you've got a reason for thinking this, and some working out to show us.

@LimeGoose I’m not pretending that WLI haven’t had an impact. I don’t know about “profound” as currently in the UK there are still vastly more obese people who are not taking them than who are, due to private cost and the limited availability on the NHS. So there won’t be whole generations of people “fully reliant” on the pharmaceutical industry any more than there already are many people who are reliant on medication. I am already reliant on medication for my high BP for life. I don’t imagine that a pharmaceutical company cares about my weight or about my BP. They care about their bottom line like all companies do. But once generics become available then there won’t be the dominance of a couple of companies like there is at the moment and these medications will become more available and cheaper.

It’s also incorrect to say that people using WLI don’t have any idea how to manage their own weight and health without WLI. I know very well how to. WLI are a tool to help me implement what I know. A really effective one for once. I’m not going to get to target weigh and then be totally mystified about how I got there or how to keep the weight off.

This idea that fat people are thick is getting on my nerves. It's actually the people who say that who are lacking in intelligence because the latest science shows just how complex obesity actually is. It won't be cured by learning how to make a salad and going for a run.

No they aren’t, 2000 people a year die from using nurofen, not one death out of over 50 million people who have used the drugs globally has been recorded for wli, the small handful of deaths, about 200 have all been down to incorrect usage ie taking a lot, or fakes,

so no they are no where near as dangerous as nurofen.

and fortunately for the health of the population, and the nhs, your opinion doesn’t count, that of all the global health authorities and the who does count and they think it should be.

honeslty I feel sorry for you but the horse has bolted sweetie, you’re going to have to accept we can and do take these meds, one day you may get them too, don’t worry,💐

i don’t think anyone should have access to it if they aren’t clinically obese, but they obviously do and I don’t have the power to stop that. Unfortunately the fanatical responses on this thread have told me we’re probably too far down the line to go into reverse now. I just hope the long-terms side effects are the best case scenario, which I absolutely don’t rule out.

Do you really care, like really, do you think this poster has more information than the scientists and doctors at the world health organisation or the fda or mhra, or any other authority globally, as I’d bet good money her opinion is based in nothing more than jealousy and resentment. So who cares.

@LimeGoose so you’re not actually at all concerned about legitimate use of WLI, but only about misuse by people accessing it who don’t meet the MHRA criteria, or perhaps healthy weight people accessing it via expensive clinics who will prescribe off label?

It’s just you seemed to be raising issues about WLI in general, not specifically just about people misusing them.

Glp-1s have been in use for type-2 diabetes since 2005 and for weight since 2014. I think we have a fair amount of research on the long term side effects.