to feel uneasy about what this means long term rather than surprised by the weight regain itself?

[HazelMember]

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

Well, yes but at no point did I say it was particularly important to me. Have a good weekend.

Well at least people have stopped pretending they're concerned or care on this thread. Now we're at the truth. You deserve to be fat. You did it to yourself and you should find the willpower to deal with it. I hate the fact that you're not going to be punished by illness and early death. Ban the medical cure and get back in the corner stuffing your mouth with doughnuts.

Yes. It's because I ate more calories each day than I burnt. However if you can't imagine many people's genetics make it a lot harder to maintain a healthy weight than others. I'm fine with ordinary hunger. I deliberately keep my dose low so I experience that. My body doesn't get just hungry though it constantly screams for food. Now I'm experiencing a normal appetite and I'm absolutely fine.

Even if you hate them at an individual level then think of the benefits to society and the public purse. I'll live a more independent life and use less nhs services. I'm footing the bill for my genetic makeup. Hurrah.

Finally, banging on about society fails to recognise that when people were slimmer they were smoking and prescriptions were regularly dished out for dangerous medicines. At their height in 1979, 30 million benzodiazepine prescriptions were written annually. By 1976, one in 20 prescriptions in Britain was for Valium. https://www.historyhit.com/mothers-little-helper-the-history-of-valium/ . In 1969, 1,700,000 prescriptions for amphetamines were made in England and Wales and that was a reduction on previous levels! https://hansard.parliament.uk/commons/1971-04-08/debates/00e3e71b-79fb-466a-9c58-4c08ffb7566e/Amphetamines. They may have been slimmer but they were drugged up to their eyeballs. No wonder they didn't have much appetite

You deserve to be fat.

Nobody, but nobody, has said or meant that.

Well at least you’re owning your bitterness and resentment now.

Bitterness and resentment of what?!

I am starting to understand the popularity of GLP1s, though.

God alone knows. Well him and you. Anyway I’m going to stop interacting with you. I wouldn’t even look your way in real life. So you’re not worth my time on here. No one cares about your opinions on fat people;

How do you know my opinion on "fat people"?!

But please do stop quoting me and making bizarre statements.

Yes they have. But it's fine. I called myself far worse every time I woke up 18 months ago. They'd rather we all pretend they're concerned or care. Anyone who can't appreciate that weight gain isn't some moral failure that's due to a lack of restraint is saying obese people deserve to be obese. I appreciate people don't like being called out on the impact of their words. I'm too old and fed up to pretend that they are motivated by concern for my health rather than the fact they hate the idea that I had proper medical support to make it possible.

Please point out where anyone has said or indicated they thought "fat people" deserve to be fat.

And how is it you know the weight of people posting?

I'll tell you what. I'll let others come to their own conclusions about the motivations of the care brigade. But at 18.20 yesterday the 'self-inflicted' debate was raging. Feel free to scroll back.

I neither know or care about people's weight. I care about their behaviour and what it reveals.

Exactly

Some folks will be able to use them to shed a few stone that has slowly built up over years of average diet and lack of exercise, or as in the case with a family member they have MS or similar and extremely limited mobility so calorie burn is difficult to manage and they slowly gain weight. Said family member has shed 3 stone that would otherwise have been impossible to lose without MJ, she’s off them now and time will tell how quickly the weight ‘piles back on’ but her diet is good in the sense she’s not an unhealthy overeater.

For others who suffer with food noise, gut dysfunction, binge eating, metabolism issues and so on the likelihood is they may need long term help in order to maintain.

Insulin resistance is self-created, behaviourally, and can be reversed, behaviourally through diet, weight loss and exercise

Right number 1

i should not have got sweary so apologies for that….though i did ask mumsnet to remove it, ideally before anyone read it 😀 so it will disappear any moment probably

your comment above is wrong, and this is the sort of thing that annoys people, there are issues that cause insulin resistance which are not self created, I have 2 of them. It is also very hard to reverse it through diet and exercise, not impossible but quite obviously more difficult to do in someone with those issues than without then

Bloody hell…see!!!!

post went two seconds ago 😀😀😀

People should stop engaging. I mean who actually cares if some random sitting at home, hiding behind a screen is getting their jollies from furiously posting on line how it’s their own fault people are fat.

I mean sure, sometimes it is, sometimes it’s mental or physical health issues that cause it.

who cares. Whatever bracket you fall into, there is a miraculous new drug out fhere which can help you become slim and healthy and stay that way.

it’s all good people.

And although you did really well reversing it with diet and exercise, honest congratulations there

it wasnt a lifetime issue…

You deserve to be fat. You did it to yourself and you should find the willpower to deal with it. I hate the fact that you're not going to be punished by illness and early death. Ban the medical cure and get back in the corner stuffing your mouth with doughnuts.

Nobody has said this. You sound like you have serious deep issues that need addressing,

The BBC are not going to stop publishing articles about WLIs and people are not going to stop discussing it.

Oh, right, but for the most part prediabetes and insulin resistance is reversed through diet and exercise and weight loss.

Insulin Resistance & Prediabetes - NIDDK

Yes absolutely can be

friend of mine is currently very overweight and when she loses a bit of weight her blood sugers do improve, she is yo yoing though, she is very petite and a foodie (not greedy as such but enjoys cooking and baking at pretty much a professional standard)

she knows it works though so is really trying hard to keep her weight low enough

Of course people will discuss it. There is a thread nearly every day on here from jeakous and resentful people about these drugs. Weight is something many people are totally mentally messed up over. Their own and other people’s.

and now there is a cure that is not widely available unless you can afford it. And it will bring out envy, resentment, etc from those who want it but can’t afford , those who have to work hard to stay a healthy weight, and think people on the drugs don’t need to work hard, or those who are a bit fat or chubby and are not eligible,

weight is a really contentious topic for many, I suspect you’re one of them.

I could probably benefit from using them for a while but I’m always a bit wary of new drugs, especially as
it is too soon for long term side affects to be known. Plus I couldn’t afford to pay for something like this long term. I don’t think I know anyone personally who takes them.

Like so many women, I gained weight when DC were younger, having been whippet thin all my life. It was, as is the case for millions of women, the result of a perfect storm of the factors we all know. Never having known 'food noise', I was suddenly drowning in it. And it was miserable. I yo-yo ketoed, HFLCed, IFed to pre-DC weight and always ended up overweight again, following considerable losses. I just couldn't manage to sustain maintaining.

In my case, a spell of extreme stress and subsequent grief caused me to drop a lot of weight over the course of 6 months. I've since been maintaining for a long time due to a realisation that I'll never be able to return to anything resembling the 'normal' I knew, ever: there'll never be a happy resting place of comfortable maintaining, just endless days in perpetuity of low-carbing and intermittent fasting, eating foods that don't really resemble 'meals' in a traditional sense, but rather studiously curated selections of items, the primary purpose of which is to fuel. 'Naturally thin' friends in my age bracket and demographic already lived like this, it turns out, I'd just not noticed.

If WLIs take the drudgery out of initial loss and subsequent maintaining, why not take them, or at the very least support other women who take them? And if a tablet or oral liquid form become the norm in the future, even better, as the plastic and sharps waste, and subsequent possible chemical landfill contamination, linked to WLIs in their current injectable iteration is worrying. I hope for a time when we're managing weight, including maintaining, by whatever healthy means and nobody suffers unnecessarily.

The fact that people on WLI repeatedly interpret anyone trying to have a discussion about a massive worldwide occurrence as being "jealous and resentful" is baffling to me. I can only conclude all of these accusations are projection of your (collective) envy, bitterness, and also anger, and aggression - which do come out in full force on these threads.

Why are you so threatened by a discussion?

Personally I don't mind these threads, they interest me. But I do think people aren't always aware of the context they're choosing to wade into. You have to be on them pretty regularly to observe some of the worst offending behaviour, as a lot of it gets deleted so there's no record. There was an absolute corker of a thread the other week where someone utterly lost the run of herself and started calling people on WLIs bad mothers, for example.

And obviously the people with the greatest interest in WLIs are those of us who are taking or considering them. So you end up with two groups. WLI thread regulars who have seen poor behaviour from people claiming to have concerns etc, and people who don't follow the subject on MN generally but whose interest has been piqued by a news article or thread title.

Yes I think you are right Binus

i don’t generally come on these threads and am shit with names so quite often miss patterns of behaviour