to feel uneasy about what this means long term rather than surprised by the weight regain itself?

[HazelMember]

I’ve just read a BBC article about research into weight loss injections like Ozempic and Wegovy showing that people who stop taking them tend to regain weight quite quickly.

I’m not shocked that weight comes back. That happens after most weight loss attempts whether they involve medication or not.

These drugs are increasingly talked about as something people might take for years or even indefinitely. That raises questions for me about what happens when someone cannot afford them anymore, when supply changes, when side effects become an issue or when a person simply does not want to stay on a medication for life.

If stopping leads not just to regain but to a fairly rapid rebound, it feels less like a temporary aid and more like something that is very hard to step away from once started. That sits oddly with how casually they are sometimes discussed.

AIBU to think the real issue here is not that people regain weight after stopping, but whether we are quietly normalising a treatment that may be difficult to discontinue once begun? Or is this simply the reality of managing a chronic condition?

Because?

A self-inflicted condition, as I said.

Look upthread^

More or less, yes. I’m overweight and I know fine well why I am!

Self inflicted

That isnt what the science says though

Theres lots of nuance and complexity to it

What about alcoholism?

I don’t have an opinion it.

I get that. I’m glad it’s available for you. But I don’t see it as a long term solution for society. It can be long term solution for individuals. And you’re right you shouldn’t have to wait for society to find this solution, I don’t believe they ever will though not when it’s more profitable to allow people to gain and then sell them a medication to loose.

It's not a matter of 'allowing' people to gain. Curb the worst frankenfood shit, yes, but most humans can now access more food than they need, for whole lifetimes. That's not stopping.

We did it with smoking though didnt we

At an individual level the person makes the choice whether to have a fag or not

But society encouraged it, it was cheap, it was glamourous

The social message changed, it was judged and judged badly, few places where you could smoke, no smoking anymore on public transport, restaurants and cinemas going no smoke areas. Hving to smoke outside in smokers corner. Age limits were increased. Packaging had warnings and then no advertising at all.
People had medical support by way of gums, patches, vapes. We didnt see it on telly as much

Imagine if this were done with UPFs.

your opinion is limited to fat people? People should refer to it as a self inflicted condition, not just a condition, it’s important to you that it’s stated it’s self inflicted when obesity is stated as a condition in front of you. That’s what you’re saying? It’s important for you that fat people are always stated as having done it to themselves?

It is a self-inflicted condition - unless you have a rare genetic disorder like Prader-Willi syndrome, or have medication-induced weight gain.

Is it?

I became peri menopausal and developed a very high cortisol problem. Google it. Then come back and tell me it was self inflicted.

Er, how else did it happen? Food entered your mouth somehow, one assumes you put it there.

One has to work around body changes, and certainly against a continued stress response.

Ok don’t bother googling then. Nor should you bother googling the resulting insulin resistance. Lol.

Okay. Don't bother looking inside yourself for a locus of control, then.

Tedious OP.

The BBC - which btw is probably the worst or at least lay persons source of scientific and current medical information - probably does have content on that, but because it also works on a business model of web traffic, will tend to entrap people like you looking for the latest headlines to get traffic.

I’ve spent 25 years in biotech and have a science background so don’t attempt to BS me with your nonsense.

You can't just pluck words at random out of a sentence and decide that is what they mean!

Internal Locus of Control means you believe you have some power to effect changes yourself.

You take some responsibility for your behaviour, you change your behaviour.

Insulin resistance is self-created, behaviourally, and can be reversed, behaviourally through diet, weight loss and exercise.

The underlying problem (as I see it) is the obesogenic environment.
We have only survived as a species because we have strong impulses to eat what ever food we can get our hands on. We shouldnt be surprised that humans can be prone to excess adipose tissue.

I do agree with this. It absolutely can be reversed through diet and exercise. I reversed my gestational diabetes in two pregnancies both with a low carb diet, and no metformin or insulin at all.

The obstetrics consultant said most women lacked the willpower to do it without any drugs, and he.was surprised I did it with nothing except the diet alone.

The thing is, the doctors probably know this is what is the true thing that focuses on reversing the type 2 diabetes caused by foods and poor diet. Surely it makes sense then that food should be the factor to reverse it too? Or is taking a drug such an easy (ahem profit making) thing that they just tell people to use it instead?

What worries you specifically?
What Skin do you have in the game?
For what other health related issues have you picked up a mantle?

Are you replying to the OP?

I think that being on the drug forever could be a fair trade off for those who had negative medical effects from being overweight. Those who just wish they were thinner to buy smaller clothes and don't really have any other problems might want to wait and see. This rebound effect has been mentioned from the start, and is one of the reasons I am still waiting and seeing.