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Is it the begining of the end for Weight loss injections?

489 replies

BeginingoftheendforWLI · 02/01/2026 18:54

Just watched a report on BBC news, they did an item on a woman who had type 2 diabetes and was prescribed Mounjaro, doctors were impressed she managed to come off insulin within a month. She had some weightloss and now goes to the gym regularly.

Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition - they simply don't have this data at present.

Feel like this is going to be big news in the foreseeable future.

OP posts:
Alpacajigsaw · 02/01/2026 19:54

chellewillnotbebeaten · 02/01/2026 19:04

I agree - admittedly I don’t need wli but I have been very overweight in the past and would have probably snapped them up at the time - early to mid twenties I fried every fad diet, pharmacy only shakes, everything (heartbreak diet solved the issue in the end haha) BUT I do think they are poorly regulated/controlled…… people are injecting insulin when they are not diabetic! That’s so dangerous! (I work in healthcare and have seen devastating effects and death from incorrect insulin management for people that actually are diabetic). Then again, I smoke and ecig and I’m sure in years to come there will be consequences with that.

What’s people injecting insulin got to do with WLI?

OP. Those of us taking them responsibly know they are serious meds but - the potential risks are less of a concern than the known risks of obesity. These kind of drugs are here to stay in how we manage and treat obesity and will improve people’s lives in a number of ways in years to come.

they are not for cosmetic weight loss they are for the serious health condition of obesity

Garroty · 02/01/2026 19:55

It's not exactly easy to get WLI for 'cosmetic' reasons. Even if someone's primary motivation for taking them is to improve the way they look, you can still only get them (safely at least) if you're obese. If you're obese you're at risk of a wide range of health concerns which weight loss can assist with. It's not like you don't get the medical benefit of weight loss just because your primary purpose is to look better.

All medication has side effects. When it comes to WLI the side effects are generally less concerning than the risks of being obese.

BeginingoftheendforWLI · 02/01/2026 19:55

TheRealMagic · 02/01/2026 18:56

What are you on about? You watched a report about a WLI success story and from that concluded that they are actually a terrible thing that will soon be stopped? Do you normally struggle with comprehension?

The report was about a success story was for the woman who had diabetes and had managed to come off insulin. People taking it for cosmetic reasons not so much.

OP posts:
usedtobeaylis · 02/01/2026 19:55

BeginingoftheendforWLI · 02/01/2026 19:51

I'm just saying what the news report said - they are great for people that need it for medical reasons, cosmetic reason not so much. Do you normally struggle with understanding basic stuff?

So why is it the beginning of the end for WLIs?

Arraminta · 02/01/2026 19:56

DarkForces · 02/01/2026 19:46

It's so lovely how many people 'care' about my health now I'm on wlis but didn't when I was obese and at far more risk. Makes me feel all warm inside.

Yes me too. I have 2 acquaintances who regularly express faux concern about my 'worrying thinness' (I'm 5ft 6 and 9st 8lbs, so hardly skin and bone).

I wonder why they never expressed any concerns when I was 3 stones heavier and mentioned my cholesterol was creeping up and up?

Nannyogganny · 02/01/2026 19:56

Garroty · 02/01/2026 19:55

It's not exactly easy to get WLI for 'cosmetic' reasons. Even if someone's primary motivation for taking them is to improve the way they look, you can still only get them (safely at least) if you're obese. If you're obese you're at risk of a wide range of health concerns which weight loss can assist with. It's not like you don't get the medical benefit of weight loss just because your primary purpose is to look better.

All medication has side effects. When it comes to WLI the side effects are generally less concerning than the risks of being obese.

'Obese' is not that big for some people.

Im a size 14 - 16. Im short 5 foot 3.

If I use a BMI calculator, It calculates me as obese. Therefore, I was able to get Mounjaro

Lolare · 02/01/2026 19:57

I say this as someone whose lost 50 pounds slowly over the course of 12 months naturally

So many of the people who I’ve seen that have lost weight using jabs look awful. Honestly like they have deflated or were stuck on a deserted island. I, in contrast, have not sagged at all (only 39 and had baby weight to lose).

Being on the jabs for life is really the only option for most. As they haven’t made the changes necessary to maintain such a loss. Who wants to be on medication for life? It will all come back. Magically switching off your appetite is not really a solution. You need to commit to genuine lifestyle changes for a healthy outcome.

Tattiana · 02/01/2026 19:58

Funnywonder · 02/01/2026 19:39

Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition - they simply don't have this data at present.

This is what stands out for me in the OP. People using the injections privately ARE doing it for medical reasons. Or health reasons if you will. It’s not all about fitting into a size 8 dress FFS.

I mean I’m sure there are many people doing it for health reasons but I think in the main it is absolutely about being thin/cosmetic. I know LOADS of people on WLIs who perhaps needed to lost a stone or two, but they certainly weren’t life-threateningly obese.

KimuraTan · 02/01/2026 19:59

I think the OP @BeginingoftheendforWLI is referring to the WLIs used without prescription to lose weight but these users not attending the gym to maintain muscle hence losing lean muscle as well as fat and thus losing strength. I completely agree - this will have huge ramifications in the future. It’s such a short sighted move to go on WLI but not build muscle and maintain strength. Natural selection 🙄

MyCatStoleSausages · 02/01/2026 19:59

Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition.

I think that this is due to people using these WLI to enable an eating disorder. I've seen it on threads here women on WLI egging each other on with I've eaten 2 peas today and couldn't possibly eat another bite. Losing weight can be addictive, I'd imagine if you are quite large then losing weight fast must feel awesome,discovering that you can eat fuck all in a day and have no hunger signals is like a cheat code to getting skinny fast.

Like anything these injections need to be used responsibly, people need to understand that food doesn't just make you fat or skinny it fuels your body and you need a certain amount of the right foods or your health will suffer. Even with that understanding though there are still people who will get sucked into thinking that it won't happen to them, they'll be fine etc. Skinny has always been desirable and some people have always been willing to risk their health to get there.

Ukefluke · 02/01/2026 19:59

Lolare · 02/01/2026 19:57

I say this as someone whose lost 50 pounds slowly over the course of 12 months naturally

So many of the people who I’ve seen that have lost weight using jabs look awful. Honestly like they have deflated or were stuck on a deserted island. I, in contrast, have not sagged at all (only 39 and had baby weight to lose).

Being on the jabs for life is really the only option for most. As they haven’t made the changes necessary to maintain such a loss. Who wants to be on medication for life? It will all come back. Magically switching off your appetite is not really a solution. You need to commit to genuine lifestyle changes for a healthy outcome.

Get back to us when you have maintained your excellent habits for a year.

BeginingoftheendforWLI · 02/01/2026 20:00

MigGirl · 02/01/2026 19:06

I am concerned about the long term implications of these drugs. I agree they are a great tool and work really well for a lot of people, but I don't agree thay they should be available over the Internet and from online pharmacies. They are a medical drug and they should be monitored by a doctor, weather that be the NHS or private.

And yes I'm aware that would make them more expensive then they are now.

Agree with you, someone talking sense. Its well known people are wearing numerous clothes and putting weights in their pockets. The medical companies don't care as they are making billions.

OP posts:
Lolare · 02/01/2026 20:01

Ukefluke · 02/01/2026 19:59

Get back to us when you have maintained your excellent habits for a year.

I have. 5 years of maintenance. No kore kids so no more baby weight. I have an eggs and veg for breakfast. And a salad for lunch. And whatever I want for dinner. That is the only regime I now follow. I make sure to walk as much as possible and rarely use my car. Even with three kids

SilenceInside · 02/01/2026 20:01

@BeginingoftheendforWLI anyone getting a legitimate private prescription from an online prescriber meets the clinical criteria for the medication. It is not for cosmetic reasons, it’s for health reasons. It’s odd that the doctor in this story apparently raised a concern about something that is nothing to do with peiple being legitimately prescribed WLI. There may be an issue with people acquiring POM illegally for conditions that they don’t have, but that’s not going to affect the legitimate uptake of WLI for those who meet the prescribing criteria.

BunnyLake · 02/01/2026 20:02

I have heard that if you don’t have diabetes then there could be some reactions from it but I don’t know what they might be. Research the meds before taking is probably the best bet.

SilenceInside · 02/01/2026 20:04

I am also quite happy that the MHRA is more of an authority on what is appropriate than concerned posters on MN.

Boohoo76 · 02/01/2026 20:04

Nannyogganny · 02/01/2026 19:56

'Obese' is not that big for some people.

Im a size 14 - 16. Im short 5 foot 3.

If I use a BMI calculator, It calculates me as obese. Therefore, I was able to get Mounjaro

A size 14-16 is big for someone of your height. Like many people, you have lost sight of what a healthy weight is.

pinkypoo8 · 02/01/2026 20:04

Oh here we go 🙄resents those on WLI – get a grip - you mean the cheaters? who aren't taking it for medical reasons - jog on

ColinOfficeTrolley · 02/01/2026 20:05

Yawn OP.

Another person who doesn't understand WLI and shows faux concern about the future of all wli takers.

People who make posts like this, I believe it's usually someone who's mate/family member has dropped a load of weight after wli's and has been getting positive attention and it pisses them off.

Always the green eyed monster lurking as they think it's 'cheating' and it really gets under their skin 😂.

Posts ALWAYS dressed up as concern.

Boohoo76 · 02/01/2026 20:05

Tattiana · 02/01/2026 19:58

I mean I’m sure there are many people doing it for health reasons but I think in the main it is absolutely about being thin/cosmetic. I know LOADS of people on WLIs who perhaps needed to lost a stone or two, but they certainly weren’t life-threateningly obese.

I was obese at 2 1/2 stone overweight.

MyCatStoleSausages · 02/01/2026 20:06

SilenceInside · 02/01/2026 20:01

@BeginingoftheendforWLI anyone getting a legitimate private prescription from an online prescriber meets the clinical criteria for the medication. It is not for cosmetic reasons, it’s for health reasons. It’s odd that the doctor in this story apparently raised a concern about something that is nothing to do with peiple being legitimately prescribed WLI. There may be an issue with people acquiring POM illegally for conditions that they don’t have, but that’s not going to affect the legitimate uptake of WLI for those who meet the prescribing criteria.

This isn't true though? I've only read a few threads on WLI here but there have been posters who have said they are 5'2" for instance instead of 5'6" so this pushes their bmi up to whatever is needed to get the drugs. That is lying to meet the criteria. In person prescribing would mean that people can be weighed/measured/monitored properly. Signs of eating disorders discovered faster etc. I don't see why anyone would have a problem with needing to go to in person clinics throughout their weight loss and it would make it safer for everyone which is a good thing.

ColinOfficeTrolley · 02/01/2026 20:09

pinkypoo8 · 02/01/2026 20:04

Oh here we go 🙄resents those on WLI – get a grip - you mean the cheaters? who aren't taking it for medical reasons - jog on

Obesity is a medical condition.

People who aren't overweight shouldn't be taking it, but why should fat people not take it? Literally paying, THEMSELVES, to assist in fixing an issue that affects many health conditions they may have.

How the fuck is that cheating? Just admit, you resent it.

Nannyogganny · 02/01/2026 20:11

Boohoo76 · 02/01/2026 20:04

A size 14-16 is big for someone of your height. Like many people, you have lost sight of what a healthy weight is.

I didn't say I was thin. I said I don't think I am obese.

Obese is the highest weight range possible

A size 14 is not obese. Should I be in the same category as someone who is 28 stone?

Boohoo76 · 02/01/2026 20:12

pinkypoo8 · 02/01/2026 20:04

Oh here we go 🙄resents those on WLI – get a grip - you mean the cheaters? who aren't taking it for medical reasons - jog on

So tell us about you….are you a fatty who is feeling under pressure as people become thinner around you or are you a thinny who is worried that they will no longer be able to feel superior around the fatties?!!

northernlight20 · 02/01/2026 20:13

Lolare · 02/01/2026 20:01

I have. 5 years of maintenance. No kore kids so no more baby weight. I have an eggs and veg for breakfast. And a salad for lunch. And whatever I want for dinner. That is the only regime I now follow. I make sure to walk as much as possible and rarely use my car. Even with three kids

Edited

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