Page 20 | Is it the begining of the end for Weight loss injections?

BeginingoftheendforWLI · 2026-01-02T18:54:53+00:00

Just watched a report on BBC news, they did an item on a woman who had type 2 diabetes and was prescribed Mounjaro, doctors were impressed she managed to come off insulin within a month. She had some weightloss and now goes to the gym regularly. Her doctor admitted that there was widespread concern in the medical field that people who were buying it privately for cosmetic reasons not for medical reasons could face some consequences in the future such as muscle growth and bone degeneration and lack of nutrition - they simply don't have this data at present. Feel like this is going to be big news in the foreseeable future.

MargoLivebetter · 28/01/2026 09:54

@T1Dmama does food rot inside the body? I've never heard of this before. Wouldn't we all have sepsis if that were the case? Where did you find out about this phenomenon. I think you should share this important medical information please.

MeridaBrave · 28/01/2026 09:55

T1Dmama · 28/01/2026 09:14

Loosing weight quickly is bad, because if you loose it too fast your body burns fat for energy but also looses muscle tone and your body feels fatigued.
when you stop using the injections and regain the weight, you regain the fat but not the muscle…. So then your body has a higher percentage of fat than before and lower metabolic rate than before before muscle burns fat!
Also the way in which these injections work
is to slow down digestion, which in turn slows down the absorption of glucose into the blood (which is the diabetes side
of things) it also works by reducing the resistance the body has to insulin.. the side effect is feeling full or feeling sick if you over eat as the undigested food seeds festering in your bowel/stomach…. It is reasonably well known in the medical field that these injections carry a long list of health risks BUT when used short term to reduce someone’s insulin resistance and put their type 2 diabetes into remission, the risks type 2 diabetes carries long term out weigh the risks of the injections short term!
Type 2 diabetes carries risks and increases your chances of developing so many illnesses due to the strain on the whole body and nervous system that comes with having high/low blood glucose… so it is deemed ‘worth the risk’ putting diabetic people in these injections if they lower these long term risks.
The same could be said if a patient is morbidly obese I guess, however it’s a short term fix and not really worth the increased health risks of being on these injections long term.
The issue comes when people who are only a bit overweight are lying on line to get these injections to loose and keep off weight, hugely increasing their risks of muscle mass loss, bowel cancers, stomach cancers (from the rotting food sitting around in their stomach or bowels longer than it should) … also risk of bowels becoming lazy/giving up .. I believe it is predicted that lots of these people abusing these injections and not being monitored by a GP ay end up with stoma bags later down the line …
Its fairly obvious really that slowing digestion and having all that rotting food sat in acid in your stomach and intestines for longer than it naturally should be is bad bad news!!

I lifted weights and ate a lot of protein and didn’t lose any muscle mass. Muscle loss is the same issue as with all low calorie diets where strength training is not a priority.

Can you point me to studies showing the cancer risk please? I don’t have “rotting food” in my stomach - I j have regular bowel movements.

Hangerbout · 28/01/2026 10:23

I’m a former amateur regional athlete who has diligently maintained some strength and fitness for over ten years since my peak. I’m definitely not at my peak anymore, but am probably stronger and fitter than the majority of middle aged women. I have many, many years of data to analyse.

I went on the drug for all of 5 months. It caused a straight line reduction in muscle mass. My power, speed, endurance also nosedived well beyond what could be reasonably expected with natural ageing. It was frightening to see the numbers drop so severely. It’s taken me the best part of a year and a half to build myself back up.

I stopped the drug because I had to conclude that, while I may have lost weight, I was setting myself up for some kind of rebound diabetes ten years down the line. This is because Muscle = metabolism. Strength also = bone health.

My fear is that the majority will not realise this is happening, even if they are an endurance runner, for example. Very few people push themselves to the max, therefore won’t clock the top slicing going on in their bodies.

I realise I might be an extreme example, but even so I predict massive health problems in a generation’s time.

I’m never going back on that drug. I’d rather be a bit fat, but strong and metabolically healthy, than slim and weak and with uncontrollable diabetes when I’m an old lady.

SwingTheMonkey · 28/01/2026 10:26

MeridaBrave · 28/01/2026 09:55

I lifted weights and ate a lot of protein and didn’t lose any muscle mass. Muscle loss is the same issue as with all low calorie diets where strength training is not a priority.

Can you point me to studies showing the cancer risk please? I don’t have “rotting food” in my stomach - I j have regular bowel movements.

Show quote history

They won’t be able to because it’s bollocks. Why do people purposely make themselves look so stupid?!

SexyFrenchDepression · 28/01/2026 10:40

MargoLivebetter · 28/01/2026 09:54

@T1Dmama does food rot inside the body? I've never heard of this before. Wouldn't we all have sepsis if that were the case? Where did you find out about this phenomenon. I think you should share this important medical information please.

Its a load of nonsense. This thread has really shown up a load of crap.

Also most people do not actually lose weight quickly they lose 1-2lb a week but consistently for a long period of time. This would be around a stone every couple of months (plus the usually 1st week or 2 whoosh like with most diets) so actually that does appear quick whilst it isnt actually. Same with muscle loss, this would happen to anyone losing weight without doing a lot of strength training alongside (which is recommended along with high protein diet when its prescribed).

I do wonder why people spout such rubbish.

Nearly50omg · 28/01/2026 10:46

My reactive hypoglycaemia I’ve had all my life even though I’ve not been overweight till menopause etc and then got pre diabetes- all stopped as soon as I started mounjaro! It’s sorted a lot of other medical conditions I have had all my life and apart from the monthly cost which I’m having to pay until the doctors sort it out on prescription I never want to stop the stuff as it’s been life changing! People will do all sorts to lose weight - but was one of them as a teenager who had anorexia badly- - but no one banned salt because people use it to make themselves sick when they have eating disorders did they 🤷‍♀️

Binus · 28/01/2026 11:15

Hangerbout · 28/01/2026 10:23

I’m a former amateur regional athlete who has diligently maintained some strength and fitness for over ten years since my peak. I’m definitely not at my peak anymore, but am probably stronger and fitter than the majority of middle aged women. I have many, many years of data to analyse.

I went on the drug for all of 5 months. It caused a straight line reduction in muscle mass. My power, speed, endurance also nosedived well beyond what could be reasonably expected with natural ageing. It was frightening to see the numbers drop so severely. It’s taken me the best part of a year and a half to build myself back up.

I stopped the drug because I had to conclude that, while I may have lost weight, I was setting myself up for some kind of rebound diabetes ten years down the line. This is because Muscle = metabolism. Strength also = bone health.

My fear is that the majority will not realise this is happening, even if they are an endurance runner, for example. Very few people push themselves to the max, therefore won’t clock the top slicing going on in their bodies.

I realise I might be an extreme example, but even so I predict massive health problems in a generation’s time.

I’m never going back on that drug. I’d rather be a bit fat, but strong and metabolically healthy, than slim and weak and with uncontrollable diabetes when I’m an old lady.

Worth pointing out that without WLIs, it's not a prediction but a certainty that we'll have massive health problems in a generations time. And now, and in two generations. Because that's what obesity does, and because sustained WLI use is the only proven way to reverse it.

DarkForces · 28/01/2026 11:44

Hangerbout · 28/01/2026 10:23

I’m a former amateur regional athlete who has diligently maintained some strength and fitness for over ten years since my peak. I’m definitely not at my peak anymore, but am probably stronger and fitter than the majority of middle aged women. I have many, many years of data to analyse.

I went on the drug for all of 5 months. It caused a straight line reduction in muscle mass. My power, speed, endurance also nosedived well beyond what could be reasonably expected with natural ageing. It was frightening to see the numbers drop so severely. It’s taken me the best part of a year and a half to build myself back up.

I stopped the drug because I had to conclude that, while I may have lost weight, I was setting myself up for some kind of rebound diabetes ten years down the line. This is because Muscle = metabolism. Strength also = bone health.

My fear is that the majority will not realise this is happening, even if they are an endurance runner, for example. Very few people push themselves to the max, therefore won’t clock the top slicing going on in their bodies.

I realise I might be an extreme example, but even so I predict massive health problems in a generation’s time.

I’m never going back on that drug. I’d rather be a bit fat, but strong and metabolically healthy, than slim and weak and with uncontrollable diabetes when I’m an old lady.

That's not been my experience at all. I've lost fat fat faster than muscle and especially visceral fat which is the most dangerous is now down to excellent levels. On top of the increasing evidence that weight loss injections reduce inflammation and the associated risks you certainly sound like an unusual case.

SilenceInside · 28/01/2026 11:54

@Hangerbout if this medication actually causes T2 diabetes, it seems a bit strange that it's used as a treatment for T2 diabetes. Can you explain a bit more about the evidence that it will cause T2 diabetes as people age?

When you were previously in a similar long term calorie deficit to lose weight, without using Mounjaro/Wegovy, what was the impact on your muscle mass and fitness then? I'm wondering about how that compares.

Personally, I would rather be at a healthy weight and take the risk of being "weak" and developing T2 diabetes as an old lady, than remain morbidly obese and probably not make being an old lady.

northernlight20 · 28/01/2026 12:16

All these posts worried about 20yrs time and when you get old, you do realise that being obese you may not have the privilege to get old? All the misinformation on here about food rotting in the tummy and losing lots of muscle. I have lost almost 7 and half stone and I havent lost much muscle and im lifting heavier than ever. Just because something happens to one person doesnt mean it will happen to everyone, sick to the back teeth of the nonsense pedaled by idiots on this thread. If you dont want to take the jab, fine, but leave others to it, jeeez, its not that hard. You dont need to make shit up to try and put others off using it.

HeidiLite · 28/01/2026 13:03

My muscle mass is great and while I'm not an athlete, my performance has certainly improved - so much easier to run or do push-ups when not carrying a few extra stone.

Nevernonono · 28/01/2026 15:35

northernlight20 · 28/01/2026 12:16

All these posts worried about 20yrs time and when you get old, you do realise that being obese you may not have the privilege to get old? All the misinformation on here about food rotting in the tummy and losing lots of muscle. I have lost almost 7 and half stone and I havent lost much muscle and im lifting heavier than ever. Just because something happens to one person doesnt mean it will happen to everyone, sick to the back teeth of the nonsense pedaled by idiots on this thread. If you dont want to take the jab, fine, but leave others to it, jeeez, its not that hard. You dont need to make shit up to try and put others off using it.

Well done or your achievements! Ignore the doom and gloom merchants!

Nevernonono · 28/01/2026 15:38

Hangerbout · 28/01/2026 10:23

I’m a former amateur regional athlete who has diligently maintained some strength and fitness for over ten years since my peak. I’m definitely not at my peak anymore, but am probably stronger and fitter than the majority of middle aged women. I have many, many years of data to analyse.

I went on the drug for all of 5 months. It caused a straight line reduction in muscle mass. My power, speed, endurance also nosedived well beyond what could be reasonably expected with natural ageing. It was frightening to see the numbers drop so severely. It’s taken me the best part of a year and a half to build myself back up.

I stopped the drug because I had to conclude that, while I may have lost weight, I was setting myself up for some kind of rebound diabetes ten years down the line. This is because Muscle = metabolism. Strength also = bone health.

My fear is that the majority will not realise this is happening, even if they are an endurance runner, for example. Very few people push themselves to the max, therefore won’t clock the top slicing going on in their bodies.

I realise I might be an extreme example, but even so I predict massive health problems in a generation’s time.

I’m never going back on that drug. I’d rather be a bit fat, but strong and metabolically healthy, than slim and weak and with uncontrollable diabetes when I’m an old lady.

Unlike massive health problems that come with obesity? Assuming you reach an older age.

3flyingducksarrive · 29/01/2026 02:17

Gastroparesis is a symptom of gastric cancers, not a cause.