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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

Artmumcreative · 22/11/2025 16:10

Does anyone know what puberty blockers actually are? Is it like taking testosterone or estrogen, or something else?

Christmasisaroundthecorner · 22/11/2025 16:17

Children do take part in medical research, where there is no alternative and generally where whatever is tested has first been tested in other ways first. Something that aims to stop physical, emotional and cognitive development is very different from other trials though. Development is such a cascade of complex interconnected biochemical processes, I can’t see how we know enough to do this without risk of significant harm.

Also, a well-designed follow up study of people who previously had puberty blockers would give much better information, and more ethically. If there were any good outcomes you would think previous puberty blocker prescribers would want this info to be known. Any organisation that blocks access to relevant data should have public funding cut off, and any individual should be struck off by their professional body.

I am so saddened to read of this trial, heartbreaking that children think that their beautiful unique selves are not good enough and that their body is wrong, heartbreaking that they do not get clear and kind support through the challenges of puberty, heartbreaking that adults who should care for them might consent to stopping their development . Appalling that researchers are earning money and aiming for academic esteem from this work when their skills are needed for other constructive research; they should really examine their consciences and ask themselves if they’d put their own children in the trial .

Ihatetomatoes · 22/11/2025 16:50

Christmasisaroundthecorner · 22/11/2025 16:17

Children do take part in medical research, where there is no alternative and generally where whatever is tested has first been tested in other ways first. Something that aims to stop physical, emotional and cognitive development is very different from other trials though. Development is such a cascade of complex interconnected biochemical processes, I can’t see how we know enough to do this without risk of significant harm.

Also, a well-designed follow up study of people who previously had puberty blockers would give much better information, and more ethically. If there were any good outcomes you would think previous puberty blocker prescribers would want this info to be known. Any organisation that blocks access to relevant data should have public funding cut off, and any individual should be struck off by their professional body.

I am so saddened to read of this trial, heartbreaking that children think that their beautiful unique selves are not good enough and that their body is wrong, heartbreaking that they do not get clear and kind support through the challenges of puberty, heartbreaking that adults who should care for them might consent to stopping their development . Appalling that researchers are earning money and aiming for academic esteem from this work when their skills are needed for other constructive research; they should really examine their consciences and ask themselves if they’d put their own children in the trial .

The research funding budget for this is almost £11 million.

The ethical considerations appear to overlooked hence why some clinicians gave concerns. Also why stop a perfectly natural process of nature due to mental health issues, surely treat that or allow time for brain development and understanding by the child of what being male or female is. It feels so wrong.

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Ihatetomatoes · 22/11/2025 16:56

Artmumcreative · 22/11/2025 16:10

Does anyone know what puberty blockers actually are? Is it like taking testosterone or estrogen, or something else?

Puberty blockers are gonadotrophin releasing hormone (GnRH) analogues, which block puberty hormone receptors to halt the progress of puberty and delay the development of secondary sexual characteristics.

Stop puberty. Some girls might love the idea of not becoming a woman with all the problems women face, but stop them from even developing naturally.... you wouldn't do it to a dog or cat, however a child.... some would do this.

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FunMustard · 22/11/2025 17:40

I don't understand why this is even needed?

Isn't there enough data from a) the children already experimented on, b) those that had puberty blockers for precocious puberty reasons? I'm sure Lupron (?) had a court case brought against the pharmaceutical company besides it caused osteoporosis in some young women?

This is despicable.

TheodoreisntBeth · 22/11/2025 17:53

DiaAssolellat · 22/11/2025 14:26

State-sanctioned child abuse

Couldn’t agree more. Which parent is going to “offer up” their child to be experimented on?

Children who went through the GIDS service were 10 times more likely to have a parent who was a sex offender, so it seems like at least some of the parents who will do that may be motivated by keeping the child prepubertal for their own reasons Sad

FelineFeasts · 22/11/2025 17:53

Ihatetomatoes · 22/11/2025 16:50

The research funding budget for this is almost £11 million.

The ethical considerations appear to overlooked hence why some clinicians gave concerns. Also why stop a perfectly natural process of nature due to mental health issues, surely treat that or allow time for brain development and understanding by the child of what being male or female is. It feels so wrong.

I was curious how a trial of 220 children could possibly cost that much, so Googled it. The figure you’re looking at is for the entire 6 year research project, not just this small trial. It includes multiple studies, including an observational study of 3000 children accessing other types of support, and detailed interviews to understand how children and young people experiencing these problems actually feel. It sounds like they’re aiming to answer some really important questions.

TeaAndStrumpets · 22/11/2025 17:57

Who will give permission for children in care?

MrsTerryPratchett · 22/11/2025 18:14

TheodoreisntBeth · 22/11/2025 17:53

Children who went through the GIDS service were 10 times more likely to have a parent who was a sex offender, so it seems like at least some of the parents who will do that may be motivated by keeping the child prepubertal for their own reasons Sad

Yuk. Have you got a link?

JellySaurus · 22/11/2025 18:16

How can a child have the understanding or maturity to consent to having no sexual function as an adult? Or to being sterilised? We have read here on MN so many posts by women in their 30s, with children of their own, who have to be sterilised because they are certain that they do not want any more children, and are refused - because they might change their minds!

Surely ‘gender distress’ is a normal part of puberty? What girl actually wants to bleed and have cramps? Growing breasts hurt! Do any of us float through puberty with no discomfort, no distress, no regrets?

If a child is so distressed by their sex and their sense of self, that they want to be sterilised and made to look like the other sex, I want to know why they feel this way. What is making them flee from their physical self? Have they been sexually abused and this is the way they think they can protect themselves? Are they gay and unable to recognise that they are OK? Are they neurodivergent and are try ing desperately to find a way to fit their round peg into society’s square holes?

Our children need psychological support and social support, not irreversible, harmful drugs alongside gaslighting that these drugs can in any way be the solution.

Ddakji · 22/11/2025 18:22

Of course a child can’t consent to having no sexual function so the consent has to come from the parent.

Which begs the question - what kind of parent consents to their child’s sexual function being damaged or destroyed?

TheodoreisntBeth · 22/11/2025 19:11

MrsTerryPratchett · 22/11/2025 18:14

Yuk. Have you got a link?

It's from Time To Think by Hannah Barnes, see pic for that and other worrying stats:

Children as guinea pigs
ContentedAlpaca · 22/11/2025 19:34

Ihatetomatoes · 22/11/2025 16:56

Puberty blockers are gonadotrophin releasing hormone (GnRH) analogues, which block puberty hormone receptors to halt the progress of puberty and delay the development of secondary sexual characteristics.

Stop puberty. Some girls might love the idea of not becoming a woman with all the problems women face, but stop them from even developing naturally.... you wouldn't do it to a dog or cat, however a child.... some would do this.

Edited

I suspect if they stop puberty they are also putting the brakes on emotional development.

Ihatetomatoes · 22/11/2025 19:40

TheodoreisntBeth · 22/11/2025 19:11

It's from Time To Think by Hannah Barnes, see pic for that and other worrying stats:

Wow

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Ihatetomatoes · 22/11/2025 19:40

Wow

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Ihatetomatoes · 22/11/2025 19:42

MrsTerryPratchett · 22/11/2025 18:14

Yuk. Have you got a link?

Omg thats awful. Child abuse by parents in plain sight

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Ihatetomatoes · 22/11/2025 23:51

Children who went through the GIDS service were 10 times more likely to have a parent who was a sex offender, so it seems like at least some of the parents who will do that may be motivated by keeping the child prepubertal for their own reasons.

How many children went through GIDS?

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Ablushingcrow · 23/11/2025 07:52

JellySaurus · 22/11/2025 18:16

How can a child have the understanding or maturity to consent to having no sexual function as an adult? Or to being sterilised? We have read here on MN so many posts by women in their 30s, with children of their own, who have to be sterilised because they are certain that they do not want any more children, and are refused - because they might change their minds!

Surely ‘gender distress’ is a normal part of puberty? What girl actually wants to bleed and have cramps? Growing breasts hurt! Do any of us float through puberty with no discomfort, no distress, no regrets?

If a child is so distressed by their sex and their sense of self, that they want to be sterilised and made to look like the other sex, I want to know why they feel this way. What is making them flee from their physical self? Have they been sexually abused and this is the way they think they can protect themselves? Are they gay and unable to recognise that they are OK? Are they neurodivergent and are try ing desperately to find a way to fit their round peg into society’s square holes?

Our children need psychological support and social support, not irreversible, harmful drugs alongside gaslighting that these drugs can in any way be the solution.

Perfectly put.

Ihatetomatoes · 23/11/2025 09:16

JellySaurus · 22/11/2025 18:16

How can a child have the understanding or maturity to consent to having no sexual function as an adult? Or to being sterilised? We have read here on MN so many posts by women in their 30s, with children of their own, who have to be sterilised because they are certain that they do not want any more children, and are refused - because they might change their minds!

Surely ‘gender distress’ is a normal part of puberty? What girl actually wants to bleed and have cramps? Growing breasts hurt! Do any of us float through puberty with no discomfort, no distress, no regrets?

If a child is so distressed by their sex and their sense of self, that they want to be sterilised and made to look like the other sex, I want to know why they feel this way. What is making them flee from their physical self? Have they been sexually abused and this is the way they think they can protect themselves? Are they gay and unable to recognise that they are OK? Are they neurodivergent and are try ing desperately to find a way to fit their round peg into society’s square holes?

Our children need psychological support and social support, not irreversible, harmful drugs alongside gaslighting that these drugs can in any way be the solution.

Exactly. Children need protection, nurturing and guidance, not stopping them from maturing into fully formed adults as biology or nature intended. Some children need good mental health support to help them love themselves and who they are, not drugs to stop puberty.

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TheodoreisntBeth · 23/11/2025 10:02

Ihatetomatoes · 22/11/2025 23:51

Children who went through the GIDS service were 10 times more likely to have a parent who was a sex offender, so it seems like at least some of the parents who will do that may be motivated by keeping the child prepubertal for their own reasons.

How many children went through GIDS?

Off the top of my head, by the time it was shut down they were 'treating' about 2500 children a year and had 4500 more on the waiting list.

FellowSuffereroftheAbsurd · 23/11/2025 13:39

It would be interesting to follow the money on this...

I do think it's really sad that we've gotten to a point where it's widely believed that there are no other options for dysphoric kids. There have been mental health options for decades, great work was done in '70s and '80s on supporting dysphoric children through to adulthood, but it's been made nearly impossible to access. That children with a wide range of mental health issues are left to suffer so greatly is a societal failure promoted by successive governments and others.

It does at times feel that they'd rather let people, especially kids suffer with mental illness if there isn't a pill or shot that can cure them. The therapy methods take resources, time, professionals - and we know even if as adults they transition that the end results are greatly improved with this care - but our systems want the option that they can make for pennies and mark up.

if you have ever met a child with gender dysphoria you will understand that this is real, but it’s also very rare. We have a relative who was 16 when he transitioned (f to m) but was expressing a desire to be a boy at 3 years old despite the fact they hadn’t even invented social media, it wasn’t mainstream etc. it is real.

It's been discussed in medical and academic writing since the '50s.

It was fairly well recognised by the '70s that gender dysphoria has multiple causes, including as a trauma response. That's why it used to be standard practice to do in-depth screening to ensure any other mental health issues were well treated before approving for transition. On hormone treatments used for cross sex hormone therapy, all the ones I've seen have depression among other mental health conditions listed as contraindications because we've known for decades that those hormone treatments can make them significantly worse.

If he went through transition before social media was invented, he would have gone through that screening and care before any medical transition. We can't compare that to what's going on today where the drugs and transition are held up as the one and only cure, not an option that is fairly extreme to be considered after other options have been fully used.

we do need carefully constructed trials, burying heads in the sand will not work, we tried that regarding gay people in the past

If we look at the experiments that were done and are still done on gay people, including children, as part of trying to 'cure' them, we can see why some are very uncomfortable with this type of medical experimenting on dysphoric kids.

And really, while shoved under the same umbrella, it's a bad comparison. Gay people are same sex attracted. Dysphoric people are distressed by their bodies and how their bodies are seen by others. The former doesn't require medical intervention and the attempts to do so have been horrible and should not be repeated. The latter benefits from mental health professionals and appropriate screening, dysphoric adults may benefit from further medical intervention or these days choose to do so, but when we already have data from these medications being used in precocious puberty of the potential permanent side effects, when we have the data from the Gender Identity Research and Education Society submitted to Parliament in defence of self-ID that the vast majority of dysphoric adults do not medically transition, when we already have decades of research on supporting dysphoric kids with therapeutic models, it is not burying our heads in the sand to question why those funding it choose to encourage the most extreme medical model for dysphoria rather than choosing to resource the mental health care we already know will benefit those who later transition and the many who won't. It's learning our lessons both that not every difference needs to be medicalised as far as possible and that quality mental health care needs better than this medical model.

Ihatetomatoes · 23/11/2025 16:38

TheodoreisntBeth · 23/11/2025 10:02

Off the top of my head, by the time it was shut down they were 'treating' about 2500 children a year and had 4500 more on the waiting list.

That's awful. 'Treating ' or abusing.

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LikeAHandleInTheWind · 23/11/2025 16:45

LVhandbagsatdawn · 22/11/2025 14:18

Point of order: children are used in medical trials all the time. Where is the outrage for those experiments, and why is it only this one which merits multiple threads on the subject?

Children are only allowed to participate in clinical trials when there is a reasonable possibility of benefit - which means drug side effects must be outweighed by benefits. In the case of pre-teens in very early stages of puberty, we don't even have animal data to know what the likely outcome from longterm puberty blockade (a year or more is considered longterm - this trial is for 2 years of treatment)

Given that 80% of children with gender questioning views find they resolve with natural puberty, I'd seriously question how unknown permanent impacts on genital development, sexual functioning, urinary continence, fertility, brain development and fertility can possibly be justified when all the existing research shows little or no impact on mental health - including from the previous Tavistock clinical trial.

LikeAHandleInTheWind · 23/11/2025 17:00

Artmumcreative · 22/11/2025 16:10

Does anyone know what puberty blockers actually are? Is it like taking testosterone or estrogen, or something else?

Puberty blockers are drugs that block the action of your normal sex hormones - so if given to children they block normal sexual development. Depending on how long you take them for puberty may not restart when they are stopped.

The justification is that when they gave trans gender identifying adults cross sex hormones the treatment didn't have much benefit - by blocking normal puberty in children the theory is that it's easier for them to pretend to be the opposite sex as adults. It really makes no sense - girls who identify as boys who are given blockers end up shorter than untreated girls. Boys given blockers then oestrogen have withered testicles and a stunted penis - so even more difficult to do genital surgery as an adult.

Also used to chemically castrate paedophiles and to treat prostate cancer.

Puzzledandpissedoff · 23/11/2025 17:18

As a result of the uncertainty over the safety of the drugs, highlighted by the Cass review into gender care, led by paediatrician Dr Hilary Cass, doctors can now only offer the treatment to under-18s as part of a research study

Last year, the government brought in a UK-wide indefinite ban on the drugs being prescribed privately or by the NHS to children and young people questioning their gender identity

I get the first part, but on the second bolded bit even a "research project" involves the drugs being prescribed, so how has this been allowed at all?