I think this depends how many people you interact with in a week.
If you are a person that works in a big team, plays sport or sings in a choir with another 25 - 30 people, is also a volunteer with groups that have quite a few other volunteers plus the people you are supporting, plus you go to Church, and you chat to your neighbours in passing, then you chat to a lot of people over the space of a week or two.
If you wfh, don't belong to any groups or teams, don't talk to your neighbours, and have only one friend you have ever kept in touch with, then you are in a different situation.
If / when I do remember someone has been away, I would ask, but - like most on this thread - would only be looking for a "Lovely thanks. Bit hot if anything, but mustn't complain", not a breakdown of any detail.
If it were some big 'once in a lifetime' tour of Canada or NZ or 3 months touring Asia or something, then I would have enjoyed keeping in touch as they travel, so would have seen what they'd been up to.