to think more negative effects will come out from Ozempic use?

[nameey]

Just read that the 30 year old singer Avery has been diagnosed with osteoporosis due to Ozempic use. Looks like this could be the start of many conditions coming out.

I know Ozempic is incredibly helpful for a lot of people but losing weight but then having osteoporosis does not seem worth it.

AIBU?

Time will tell, I'm sure. It's distasteful how people seem to almost be keen for dire side effects to be inflicted on people taking Wegovy or Mounjaro for obesity. Hence seizing on these stories of foolhardy people experiencing issues after making stupid choices, and suggesting it's an issue for people who are taking the medication because it was appropriately prescribed to them.

What was absolutely certain for me was dire health outcomes from remaining morbidly obese. So as with many decisions, it's a balance or risk versus benefit and it's clear what the outcome of that balance is for me.

I would suggest she got osteoporosis from her eating disorder long before Ozempic. But hey, if it makes you happy.....

And you will be first in the queue rubbing your hands together saying "Bad fatties, it what you deserve"

Absolutely this. It's the most bizarre, petty bitchy thing I have ever seen.
Of course dressed up as "concern". Because of course they get "concerned" for users of every drug on ye market. 🙄. Not.

Because like a lot of unpleasant women, she can't bear the thought of fat people losing weight because she won't have anybody to look down on in her pathetic bitchy life.

Yes but paracetamol risks don't give bitchy women the excuse to criticise fat people in the guise of faux "concern"

and I bet you can't weight......

They are lovely aren't they? Such genuine concerned people. 🙄When do they ever sleep what with worrying day and night about side effects in every person on earth taking every drug ever marketed......... oh wait........ They arent.

Perhaps if all those "concerned" people were less offensive......

Except...... that's not what it does.

I don't think it would be surprising if more effects came out. I think any kind of drug that has such a wide system effect has a high chance of having some unexpected side effects that will emerge as they are used by more people for longer periods of time.

Look at Depo-Provera, for example, many people were assured it was very safe, I know people that have been taking it for 20 years. Now there are two class action lawsuits, one around brain tumors.

Of course with someone very obese, or diabetic, the risks of that might well justify those unknowns, but I think it's important not to fool ourselves that serious side effects could well emerge.

Can you name a single medication that doesn’t have any side effects?

Honestly, anyone would think this is the first medication to emerge with links to possible side effects. Apparently someone on this thread went to the States and saw an advert for wegovy that listed numerous side effects. But they didn’t see adverts for any number of medicines with a long list of side effects recited at the end of each and every one of them. Just wegovy?

Medicines have side effects. All of them. The user must weigh up whether the potential side effects are worth it for the benefits of the drug. Which is what lots of people are currently doing with WLI. And with 30000 people in the UK dying each year, from obesity related diseases, I’d say it’s a punt worth taking.

Can somebody start a "concerned" thread for me and others who were prescribed Methotrexate ........ a drug so toxic that you have to have your blood monitored every month. Adverse reactions include ulcerative stomatitis, leukopenia, nausea, and abdominal distress. In addition, infections, malaise, fatigue, chills, fever, Thromboembolic events (including arterial thrombosis, cerebral thrombosis, deep vein thrombosis, retinal vein thrombosis, thrombophlebitis, and pulmonary embolus), pericarditis, pericardial effusion, hypotension, sudden deathToxic epidermal necrolysis, Stevens-Johnson syndrome, exfoliative dermatitis, skin necrosis, and erythema multiforme, erythematous rashes, pruritus, alopecia, skin ulceration, accelerated nodulosis, urticaria, pigmentary changes, ecchymosis, telangiectasia, photosensitivity, acne, furunculosis. Potentially life-threatening hepatotoxicity, pulmonary damage, and myelosuppression.

And that's just the first half page of about 20 pages.
A very toxic drug that's not even the best treatment but it's the go to as its cheap.
Did I mention the birth defects and carcinogenic properties?
Weight loss injections aren't even in the same league.

I want a concern filled thread from all the drug side effect concerned folk because I know they will know all about it because they will be just be as well read on all drugs as they are on Ozempic🙄. I simply can't understand why I haven't seen 200 “Deeply concerned about Methotrexate" threads. Can't figure it out at all........ 🤔

I think there’s quite a big difference in being informed between getting properly prescribed medication that you genuinely fit the criteria for, reading the info leaflet, taking the meds the right way, and being aware of developing scientific thought, and reading endless threads with Daily Mail links to stories with bad stats, inaccurate information, and zero research, and posters who were told by their sister in law’s friend who’s a dental nurse, and ‘someone told me once they kill you’ contributions.

Those drugs are all amphetamine based, a class of drugs with significantly worse side effects then GLP1s

One of the safest things you can do in drug development is repurpose an existing drug as you have in this case 3 decades of human data on the drug. Long term use has been shown to have far more benefits then negative effects.

https://www.bbc.co.uk/news/articles/c9d5pq4y5wpo

The use of these drugs are also so safe their use is being expanded having just been approved to adress chronic kidney disease in diabetic patients and clinical trials for a variety of things including neurodegeneratove disease like alzhimers disease and parkinsons where other effective treatments are massively lacking.

Unlike amphetamines which due to side effects have very very limited uses.

Those drugs are all amphetamine based

That is not accurate.

OK sorry I didn't read It properly but the rest of it stands.

Unlike previous drugs GLP1 has a very safe profile with 30 years of human data.

They are also very effective. I mean a 2inute Google says the first one you mentioned was pulled due to ineffectiveness alongside an increase in risks.

The risks of this class of drugs are minimal and the drug is very effective at reducing obesity.

https://pmc.ncbi.nlm.nih.gov/articles/PMC8878541/
The effect of GLP 1 agonists on osteoporosis appears to be neither protective nor a risk of these drugs ie it has no effect.

This is based on a systematic review of the existing literature not a single case of an individual who missed the drug and developed it most likely die to her eating disorder.

I’ve just had some post menopausal bleeding and referred on the cancer pathway. My recent weight loss, using Mounjaro, significantly reduces my breast, uterine and ovarian cancer risk. It’s also lowered my blood pressure meaning, I’m now at less risk of stroke, heart disease and kidney failure.

I'm not going to argue the toss, point by point, however, just from the wiki entry I linked:

"Fenfluramine was marketed by American Home Products (later known as Wyeth) as Pondimin, but was shown to cause potentially fatal pulmonary hypertension and heart valve problems, which eventually led to its withdrawal in 1997 and legal damages of over $13 billion."

Fenluramine had a weaker effect on its own. It was available from the 1970s to late 90s. Fen-Phen was a combo drug that was considered a wonder drug for weightloss in the nineties, until the reports of heart problems started flowing in, and a number of deaths from heart problems in users occurred. It was also viewed as useful for drug addiction... Wyeth set aside $21.1 billion (U.S.) to cover the cost of the lawsuits.

Given there are already class action lawsuits in the States, involving Ozempic, Rybelsus, Wegovy, Trulicity, and Mounjaro, from people claiming they weren't properly informed of the risks, I really don't think you can say "the risks of this class of drugs are minimal".

I agree that these drugs have been around for a long time, so the risks and side effects are very well known. What's changed recently is their use solely for weight loss, and the instances of inappropriate prescribing.

People have misused/abused drugs since the beginning of time, which means there has to be education and controls.

Personally I think that they are an absolute game changer, with even more potential to combat some of the lifestyle diseases our modern world has inflicted on us.

What would be even better is if we banned UPFs from the planet, reducing the problems that these drugs are needed for in the first place.

@lettyraines can you link to the class action lawsuits against MJ? This link suggests there aren't any. www.drugwatch.com/legal/mounjaro-lawsuit/

I just googled law suits against Ozempic & Wegovy in America and there are some law suits … not sure about class action law suits as was just a 5 minute search.

Most of the cases seem to focus on the manufacturers not giving enough warning of the possible side effects. Which I think is nonsense really as in the UK at least the potential side effects are clearly listed in the leaflet that comes with the drug. I suppose the issue is not everyone reads the information properly which personally I feel is their responsibility & not the fault of the manufacturer.

Wow. I’m surprised. Again. Just how many people are so jealous and resentful over these drugs. it’s a small number but bloody heck, the obsession, I feel pity.

The lawsuit comment actually made me laugh out loud, it was similar in vein to the op blaming the drug in the op and shows a lack of knowledge, or a desire to use anything,

the bottom like is all drugs have risks. 2000 people a year die from nurofen. There is no prescription med without a warning on the label.

the risks of obesity are signficant. Very signficant.

in the USA nearly 17 milllion on the drugs, less than 300 deaths, not one proven to due to correct usage of a legitimate drug. The stats speak for themselves.

the thing I don’t get is, how can you be so obsessive and consumed by something that doesn’t impact you that you start posting shite all over the internet. In some odd futile attempt to get people to stay fat and struggle

you can’t get them, tough shit. You want to have slim privalge, tough shit. It’s gone. You want others to work as hard as you to stay slim. Tough shit.

the horse bolted.

You can take out a law suit about anything to anyone in the US and it will drag along, it doesnt mean it has any validity.