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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

See all MNHQ comments on this thread

to think more negative effects will come out from Ozempic use?

692 replies

nameey · 22/02/2025 11:12

Just read that the 30 year old singer Avery has been diagnosed with osteoporosis due to Ozempic use. Looks like this could be the start of many conditions coming out.

I know Ozempic is incredibly helpful for a lot of people but losing weight but then having osteoporosis does not seem worth it.

AIBU?

OP posts:
soupyspoon · 23/02/2025 18:38

Arraminta · 23/02/2025 17:55

Yes, I haven't heard a peep from her either, despite my having taken Tamoxifen for several years. You know, the prescribed drug that, whilst protecting you from a breast cancer reoccurance, has also been proven to damage your heart and increase your risk of strokes and uterine cancer!

Presumably the OP doesn't care because I can now comfortably wear size 10 jeans after 6 months on MJ?

I'm deeply hurt.

Well Im deeply concerned, to the degree Im sitting here with crossed arms, pursed lips and a quizzical eyebrow.

HOW can they justify giving you such a risky med? I mean breast cancer, yada yada yada, these medications just shouldnt be allowed?

SwingTheMonkey · 23/02/2025 18:42

soupyspoon · 23/02/2025 18:38

Well Im deeply concerned, to the degree Im sitting here with crossed arms, pursed lips and a quizzical eyebrow.

HOW can they justify giving you such a risky med? I mean breast cancer, yada yada yada, these medications just shouldnt be allowed?

Please make sure you start a thread so we can all give our uninformed opinions on whether any other serious side effects might show up in the future so that pp might have second thoughts over taking such a dangerous medicine! (That’s currently saving her life…)

Arraminta · 23/02/2025 19:00

soupyspoon · 23/02/2025 18:38

Well Im deeply concerned, to the degree Im sitting here with crossed arms, pursed lips and a quizzical eyebrow.

HOW can they justify giving you such a risky med? I mean breast cancer, yada yada yada, these medications just shouldnt be allowed?

Well, at last! I'm so relieved that someone actually cares about me [weeps]

soupyspoon · 23/02/2025 19:00

SwingTheMonkey · 23/02/2025 18:42

Please make sure you start a thread so we can all give our uninformed opinions on whether any other serious side effects might show up in the future so that pp might have second thoughts over taking such a dangerous medicine! (That’s currently saving her life…)

I think I should, its virtually a public duty to ensure people are kept informed and discussion continues.

Arraminta · 23/02/2025 19:02

SwingTheMonkey · 23/02/2025 18:42

Please make sure you start a thread so we can all give our uninformed opinions on whether any other serious side effects might show up in the future so that pp might have second thoughts over taking such a dangerous medicine! (That’s currently saving her life…)

Yes, I'm ideally looking for opinions from posters who aren't actually any good at thinking and like to cite The Daily Fail as their reference material.

SwingTheMonkey · 23/02/2025 19:04

Arraminta · 23/02/2025 19:02

Yes, I'm ideally looking for opinions from posters who aren't actually any good at thinking and like to cite The Daily Fail as their reference material.

Or those who have a very vague understanding of the medicine but who like to comment as if they’re experts… Or those whose friend’s auntie’s next door neighbour told them it was really, really dangerous.

Tulipsandaffodils · 23/02/2025 20:22

Arraminta · 23/02/2025 18:28

Anyway, once the patent for Mounjaro expires (in about 20 months, I think?) the cost will drop dramatically (probably somewhere between only £30-£40 per month?).

At which point, these faux concern threads will simply disappear.

No that’s ozempic , mounjaro is about 2036.

lettyraines · 23/02/2025 20:34

Glorybox2025 · 23/02/2025 12:27

People who were obese and are no longer obese due to following a treatment plan including WLI will be entitled to remain on WLI once they reach a healthy BMI in order to maintain the healthy BMI

It's really not that difficult to understand if you think about it for more than a minute. Obesity is a chronic condition - once you have it, it's very hard to lose it. Even losing weight doesn't mean you have lost the tendency to obesity. Compounded with the fact that we live in an obesogenic society it's clear we need a treatment that helps maintain long term treatment for obesity. Time will tell how long people need to maintain for before their bodies no longer tend towards weight gain after a period of obesity, whether that's months, years or never, but there is absolutely no suggestion that anyone who has used WLI to reduce their BMI will no longer be entitled to take it once they reach a healthy BMI.

This seems to suggest that people imagine they will - whatever brandname or drug they are on - be using the injections for life, not the two years mentioned above for semaglutide.

Yes I think it is common knowledge that wegovy is for two years and mounjaro for life.

Tulipsandaffodils · 23/02/2025 20:39

lettyraines · 23/02/2025 20:34

This seems to suggest that people imagine they will - whatever brandname or drug they are on - be using the injections for life, not the two years mentioned above for semaglutide.

Yes I think it is common knowledge that wegovy is for two years and mounjaro for life.

common knowledge means most people, not everyone.

lettyraines · 23/02/2025 20:44

Tulipsandaffodils · 23/02/2025 20:39

common knowledge means most people, not everyone.

I know what common knowledge means. That poster was one of the most coherent on this thread, so I was surprised to learn she was not aware of this 'common knowledge'.

Tulipsandaffodils · 23/02/2025 21:42

lettyraines · 23/02/2025 20:44

I know what common knowledge means. That poster was one of the most coherent on this thread, so I was surprised to learn she was not aware of this 'common knowledge'.

Ah ok,

Gardenservant · 23/02/2025 21:53

As a pharmacist I have a rule never to take new medication unless it would be a matter of life and death. I have seen far too many wonder drugs withdrawn over unexpected side effects after a time. That said, I might take it in about 5 years when facts about side effects will be clearer, I would love to lose weight.

SwingTheMonkey · 23/02/2025 21:57

Gardenservant · 23/02/2025 21:53

As a pharmacist I have a rule never to take new medication unless it would be a matter of life and death. I have seen far too many wonder drugs withdrawn over unexpected side effects after a time. That said, I might take it in about 5 years when facts about side effects will be clearer, I would love to lose weight.

Ah, you’ll be ok with this one then because it’s not a new medication.

Gardenservant · 23/02/2025 22:05

SwingTheMonkey · 23/02/2025 21:57

Ah, you’ll be ok with this one then because it’s not a new medication.

Too new for me. New is relative.

Glorybox2025 · 23/02/2025 22:07

lettyraines · 23/02/2025 20:44

I know what common knowledge means. That poster was one of the most coherent on this thread, so I was surprised to learn she was not aware of this 'common knowledge'.

I am not sure if you're directing this comment about 'common knowledge' to me, or which poster you are referring to being the most coherent. You did quote me but I'm not really following your point. In any case, yes, many people will be on WLI long term if not for life.

Tulipsandaffodils · 23/02/2025 22:08

Gardenservant · 23/02/2025 22:05

Too new for me. New is relative.

As a pharmacist you know this peptide has been in use for over 20 years right. What makes 25 thr magic number, as you said another 5?

Jackiepumpkinhead · 23/02/2025 22:09

nameey · 22/02/2025 19:29

Just because people don't post about it here does not mean they are not concerned about other prescription medication. I have been concerned about many other prescription medicine also.

So much worry about things that don’t concern you!

SwingTheMonkey · 23/02/2025 22:10

Gardenservant · 23/02/2025 22:05

Too new for me. New is relative.

So another 5 years will do it, when it’s been used for a couple of decades already? That doesn’t make a lot of sense…

nameey · 23/02/2025 22:11

Gardenservant · 23/02/2025 21:53

As a pharmacist I have a rule never to take new medication unless it would be a matter of life and death. I have seen far too many wonder drugs withdrawn over unexpected side effects after a time. That said, I might take it in about 5 years when facts about side effects will be clearer, I would love to lose weight.

Well said 👏

OP posts:
Tulipsandaffodils · 23/02/2025 22:12

SwingTheMonkey · 23/02/2025 22:10

So another 5 years will do it, when it’s been used for a couple of decades already? That doesn’t make a lot of sense…

Not to me either, but the ops loving it, 😂

lettyraines · 23/02/2025 22:12

Glorybox2025 · 23/02/2025 22:07

I am not sure if you're directing this comment about 'common knowledge' to me, or which poster you are referring to being the most coherent. You did quote me but I'm not really following your point. In any case, yes, many people will be on WLI long term if not for life.

Somebody said this:

Yes I think it is common knowledge that wegovy is for two years and mounjaro for life.

I was surprised, as in answer to my question about what a person is to do once they get to a normal weight, you wrote what I felt at the time was a coherent explanation in reply, but it seemed from that particular post you were not aware of this 'common knowledge'.

SilenceInside · 23/02/2025 22:24

@Gardenservant I don't think that 5 years on top of the decade that tirzepatide has been researched for is going to reveal any significant adverse effects. And, as someone who was morbidly obese, remaining morbidly obese for 5 years is most definitely going to cause me health issues. So it's a clear benefit versus risk situation, for me.

Semaglutide has been studied and used for longer than tirzepatide as well.

Glorybox2025 · 23/02/2025 22:27

lettyraines · 23/02/2025 22:12

Somebody said this:

Yes I think it is common knowledge that wegovy is for two years and mounjaro for life.

I was surprised, as in answer to my question about what a person is to do once they get to a normal weight, you wrote what I felt at the time was a coherent explanation in reply, but it seemed from that particular post you were not aware of this 'common knowledge'.

I don't actually think that is 'common knowledge' - not the way you're understanding it anyway. Wegovy is currently approved for use for 2 years on the NHS but there is no limit on how long people can take it for as per its licence/approval. Mounjaro is also recommended for a maximum of 2 years by NICE guidelines but can be taken longer term if prescribed. The bit of my post you seem to be linking this to is where I said that it's not yet known whether this medication will need to be taken for life in order to prevent recurrence of obesity. It can't be 'common knowledge' that people will need to take Mounjaro for life because it's not known yet. However potentially people could take both Mounjaro or Wegovy for life if their prescriber will prescribe it and it continues to be effective.

lettyraines · 23/02/2025 22:37

I think it is already pretty obvious that most people using these injections will need to be on them for life, as most people who've lost weight using these injections have regained a substantial amount of the lost weight once going off the injections.

I have been told it's 'common knowledge' you can't stay on them, and then that you can stay on them.

Gardenservant · 23/02/2025 22:38

Ozempic was approved for use in 2017. Thalicomide was usedfor aprrox 10 years before it was withdrawn.

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