To think all these weight loss jabs are a bad move?

[Pineconecollector]

I’ve seen so many people recently saying they’re on Mounjaro - someone wrote on Facebook that they were struggling to eat anything at all, hadn't eaten for over 48 hours. Just zero desire to eat anything. Surely that can’t be healthy?

I also know of someone who has lied to an only e pharmacy to get the jab, because her BMI would be considered too low to be prescribed it. She’s wanting to get down to a size 6.

Since these drugs have not been tested on teens/ immature body I would hold fire.
We have no idea what it will do longterm to the pancreas.
Far better to start with good eating habits from the start of life rather than try and fix established poor eating habits.
Like most modern health issues it is complicated. Maybe huge taxes on fast food will both fund future weight loss on the NHS and maybe prevent obesity long term.

The IPO certificate for semaglutide has an expiry date of March 2031 (https://www.ipo.gov.uk/p-ipsum/Case/PublicationNumber/EP1863839)

Addiction too.

It's fascinating, right? Pathological gambling, shopping addiction, drug, smoking

BMJ was full of it in September
A miracle drug indeed

I mean, that shouldn't stop the naysayers and the OP from ignoring the science and being terribly worried😄😄😄

Now all we need is a wonder drug to help people with a compulsion to project their own disordered relationship to food and/or body image on snarky threads on social media.

Actually they have been tested on teens (see attached) and have been used in the UK paediatric weight loss clinics such as the one at Southampton hospital for several years.

My son is on tirzepatide under a prof of endocrinology and a team of paediatricians with direct and regular consultation with Eli Lilly. He’s 16.5yrs, 6ft 3, and was 20st after 4x covid, glandular fever and a post viral illness, that revealed early stages of fatty liver disease and hypothyroidism (the latter like his mum, I’m afraid). Due to his autism he is also mildly dyspraxic and found exercising very difficult as he started to gain weight and with post viral complications of covid. After 8 weeks he is 1.5st lighter and looking forward to joining the local gym/starting a programme now that he is less obviously big. His self confidence is growing by the day and his mood is so much better. He is looking forward to his next round of blood tests and not scared of his next liver scan in 3m, which we hope will have totally reversed the liver issue. It’s impacted everything down to grades - straight As on A levels - sleep, focus and drive.

https://www.tctmd.com/news/semaglutide-effective-weight-loss-adolescents-step-teens#

@CautiousLurker1 so great that your son has received the medication that he needed to live such a good life!

Thank you @Motnight

He was severely anxious and low in mood during GCSEs and didn’t do as well as expected, so moving up to college and getting As, having the confidence to make new friends has been extraordinary to watch, esp given he’s on the autism spectrum.

He now believes University is possible and wants to be as healthy and active as possible to make the most of every bit of it. Am so pleased he didn’t have to wait another 1.5- 2 years to be prescribed.

@CautiousLurker1 that's wonderful, you must be thankful that we live in an age where these medications exist and are available to help people like your boy xx

I have seen a lot round adhd too. My mind is so bloody clear since I started taking it. I can actually focus on tasks now- makes me much more productive at work now. Mind you adhd and weight gain are interlinked.you’re 5 times more likely to be overweight if you have adhd.

Since starting to take this I am getting glimpses into what it must feel to be normal, actually being able to concentrate on a spreadsheet or admin task at not having to settle anxiety with constantly chewing/eating food. I went into boots the other day to pick up some make up, I looked round the food bit and thought, I don’t fancy any of that - before I would have left with at least a bag of crisps. I no longer think of food 24:7, no longer have the compulsion to constantly chew

God to feel like this without medication, to have gone through the past 50 ish year like this, how things might have been different. Thank God future generations will have this and hopefully further research into all the barriers to weight loss and a better idea on how to improve quality of life.

This resonates with me so much as it's exactly what happens when I drastically reduce my insulin dosage. The hunger disappears in a flash and I suddenly realise what it's like for non-fat people and how they can eat normal portions.

But I'd be dead if I did it for more than a day or two so I live with the constant artificial hunger. I'm not on weight loss jabs but I wonder if the naysayers would think I'm more deserving of a medication since it's another medication making me fat in the first place...

You really need to read up, honestly. You’re posting such erroneous stuff, these drugs have been used close to two decades. They do know what happens to the pancreas. You don’t, fair enough, but don’t say we. They have been tested on teens and immature bodies.

I understand you’re upset and annoyed people can now take medication and get slim, for reasons I doubt you will reveal. But making stuff up and posting it is a little silly. As is the faux concern about teenage girls. But no mention of the other drugs available on thr black market to young people, the addictive drugs, the damaging ones. Or the teenage girls who will be eligible to take it.

whatever is causing your upset. Be it you can’t afford them yourself and want them, or don’t want people to be slim, whatever, posting erroneous stuff isn’t ok.

I don't resent anything. It's just a direction of healthcare I personally don't feel comfortable with.

I'm overweight myself, I don't have some beef with fat people. I think you're really assuming the whole world hates you, based on very little.

I think we're quite lucky here in terms of healthcare in this area - I've had a number of health problems since having a baby and seen multiple GPs, nurses, physios in person over the past couple of years. Sometimes it's a phone appointment but only as a follow up.

Are you unaware that much of the country is struggling to see anyone face to face. And has been for some time?

Read up! Honestly, check yourself. The poster you are patronising has a far better understanding of these matters than most on this thread.

And as I also posted, and was chased about for what felt like many days for noting, the drugs have been used for many years for those with type 2 diabetes - at a lower dose. As per this article:

"When used for overweight or obesity, the drugs are typically prescribed in higher doses than when prescribed for diabetes."

GLP-1 diabetes and weight-loss drug side effects: "Ozempic face" and more - Harvard Health

The more severe adverse effects are already well known. For example:

gastroparesis
bowel obstruction
pancreatitis
gallstones

Also, some opthamologists warn of vision loss. As vision loss can be an outcome of type 2 diabetes, due to diabetic retinopathy, it is monitored and the risk/benefits of the drugs weighed up. Recent studies warn of loss of bone mass, as well as muscle mass, increasing osteoporosis risk. Personally, I would not want to risk my eye sight (or the function of my digestive system - which is what the US class action lawsuit is about) for the sake of easier weight loss. I am happy to lose weight the boring, slow, but not dangerous way.

Everyone who dares to suggest caution on this thread is accused of being "silly", "jealous", of making things up, and my favourite, writing "pretend comments". I am not jealous of those on these injections, any more than I am jealous of those using amphetamines or any other weightloss-enducing pharmaceuticals.

It's not as if this is our first rodeo with miracle weightloss discoveries. Orlistat was the rage just a decade or so ago, but has fallen out of favour, perhaps due to the number of people soiling themselves inadvertently...

Here is a list of weightloss drugs that were on the market for some considerable time before being withdrawn due to adverse effects/deaths:

Centrally Acting Drugs for Obesity: Past, Present, and Future - PMC (nih.gov)

Oh do bore off poisongreen, your posts are full of inaccurate nonsense that you seem to want to keep promoting for reasons that are unknown. Weird.

Innacurate nonsense! You do seem threatened by any fact. Odd.

Nope, just not facts. Inaccurate nonsense as I've already said. Designed to mislead, for reasons unknown.

Oh, yes, Harvard Medical School - famous for its "innacurate nonsense".

Are you referring to @Angrymum22? Who has been consistently proved wrong. How does that indicate a far better understanding than most?

Have you studied medicine?

No, I mean the inaccurate nonsense that you've written poisongreen, of course.

I don't even need to discuss the Harvard article as anyone with half a brain reading it will realise that it is a reasonable article that accurately represents the possible side effects of weight loss injections. I have no idea what point you think you're making by linking it. Even the introductory paragraph immediately debunks the idea of "Ozempic face" by correctly saying that it's a risk of any kind of weight loss.

The quote about higher doses is also misleading bollocks. It could only be reasonably applied to Saxenda, which can be used at higher doses for weight loss than typically used for diabetes but doesn't have to be as it depends on the patient. It's totally irrelevant to Mounjaro and Wegovy which are used at the same doses and have been researched at those doses for people with obesity only rather than also with diabetes.

I mean, this has been covered comprehensively on this thread but you just keep returning to post it again and again.

Good recovery!

Perhaps you could point out the precise "inaccurate nonsense" that I have written.