YANBU OP. I might feel more optimistic if there was actually some kind of credible plan or vision for the country, but the current shower of shite in charge would get sacked from any professional job in the real world for lack of competency. They’re anything but “conservative”.
Before 2016, the U.K. was a world leader on biomedical research and pharmaceutical research and development. The MHRA was a highly respected government agency, on a par with FDA in the USA and BfArM in Germany. The expertise was so well regarded that when the European Medicines Agency was established, the natural home was London. The U.K. punched well above its weight and made a huge contribution to the science, law and policy around medicine regulation in Europe, bringing together folk from all over the EU and folk from other parts of the world came to learn from them.
Post Brexit, EMA had to leave the U.K., as by the law that established it, it had to be located in a member state of the EU. It went to Amsterdam. May’s Withdrawal Agreement made no attempt to have some kind of work sharing agreement between MHRA and EMA, it was the hardest of exits. As a consequence huge numbers of MHRA staff left just as the work dramatically increased because a) covid and b) now MHRA also have to do everything that is done by EMA on behalf of all member states, with no plan in place and an impossible situation in NI because of the border kerfuffle. MHRA in a few short years has become a shell of itself. Anyone trying to run a clinical trial in the U.K. knows that it’s currently impossible to get approval to normal timelines due to a lack of staff reviewing the paperwork which means that part of the industry is also fast declining in the U.K. as companies will just run them elsewhere in Europe instead.
the UK government recently announced that basically in the future, if a medicine is approved by another “big” agency like EMA or FDA then MHRA will just rubber stamp it and let it be sold in the U.K. Which is pretty much what countries with no significant expertise do, eg most of Africa and the Middle East. The trend worldwide for years is for countries to develop their own expertise, not rely on the big agencies so much and to ask harder questions, like requiring data in patients that match the ethnic makeup of their populations. Not to go dramatically backwards in scrutiny!
I’ve had a ringside seat for the decimation of an industry in five short years. It can’t be the only one, and if it’s indicative of what the rest of industry is going through then it’s an utter travesty, and I don’t have enough swear words to express what an almighty clusterfuck we’ve inflicted on ourselves as a country. It’s a complete abdication of the basic responsibility of government to ensure the country has a sound basis for a society and we should be rioting in the streets.