I have done it too... (ghosted someone.) ONCE ... I met a woman around summer 2016 at the local Ladies group in my village. She lives not too far away from me. 15 mins walk... They moved into this village around early 2016, and I met her and her partner at the pub. She and he seemed okay when me and DH met them. We all went to the pub a few times, and for a few meals over about one and a half to two years.
Unfortunately, the more we got to know them, the more we disliked them, and the more loathsome and dislikeable they became. They were very homophobic, very racist, and very critical and bitchy. They bitched about the female vicar, and didn't understand how a woman could be a vicar. They also derided and berated other people in the village. Including insulting peoples ginger hair, and freckles, and had a pop at peoples weight!
They seemed really shocked that my husband let us let me use OUR car. And sneered at women who had children out of wedlock. THEY were childfree and weren't married, and it was because he wouldn't marry her. She moaned all the time about how wrong it was that they weren't married. Met in 2003, and no ring. He earned 2.5X more than her too and never shared anything with her, making her pay for everything herself. It was a hilariously toxic relationship, yet she was SO judgy and up herself.
There was one particular woman in the 'Women's group' that I used to go to in the village (about 15 women,) who was about five years younger than her, in her mid 40s, and she didn't work. And this 'friend' of mine was relentless in constantly asking her why she doesn't work, how she can't work, when she's going to start work again. Work, work, work, work, work.
After about the 10th time, of being grilled in 10 weeks, this woman just stopped going to the group and she told me (much later,) that this so-called friend of mine was the reason why.
There's a number of things apart from the nasty catty way they spoke about people. She wanted to know how me and my husband could both afford to just work part time, and how we were mortgage-free by our mid 40s! And HE made comments about my husbands weight. (DH is always 2-3 stone overweight so not much, and he is gorgeous- this man was 9 and a half stone, 5 ft 3 and a keen cyclist without a scrap of body fat. SO this meant he could call everyone else FAT obviously. And she made sarcastic comments about another woman's daughter doing a 'masters' saying 'oh forever in education never growing up, eh?' 
Constantly calling and texting me wanting to talk about how she hated her job and hated the kids in the families in the cul de sac she lived in. Bought a FOUR bed house with her and her partner, in a cul de sac of 12 FOUR bed houses, and was shocked that there were a lot of children around! And if I didn't answer her text back within 15 minutes she was at my door. Moany, mean-spirited, bitchy, racist, homophobic, boring, critical. Her partner was the same.
After around 2.5 years, I actually had to completely block and ghost her AND him, as I was getting so stressed out. She really got me down... There's no easy way to say 'will you please fuck off ... because I hate you, you fucking arsehole... !' So sometimes you do have to ghost people.
4 years later, and I still have no regrets. I have passed her a few times, and looked the other way. She mithered and pestered me for about 6 months via text and phone messages and emails, and I ignored every form of contact. She even got a couple of the other women in the ladies group that we went to, to grill me and find out why I haven't been in touch with her. (I stopped going when I decided to ghost her, but I saw them at the village cafe...) I just kept saying, 'the more I got to know them, the more I realised we have got nothing in common really. We just became friends at the beginning because they were new to the village and I wanted to be friendly but they got too attached. But we've got nothing in common.'
I wasn't going to say there were problems because these two women she kept asking are actually really nice and they would have tried to 'fix' the problem. I didn't want anything 'fixing.' I just wanted this fucking woman out of my face, and out of my life. AND her hideous 'partner!'