[quote BigYellowTaxiT]@Patchbatch You could try to be less patronising with your “I look forward to some random research paper” crap.
There is a lot of recent research looking into the genetic risk factors of eating disorders and how weight loss (for whatever reason) can trigger a biochemical / neurobiological response.
One important, large, study published in Nature Genetics (2019) looked at nearly 17,000 anorexia cases and identified eight genetic variants associated with the disorder. This study highlighted very clearly that anorexia nervosa isn’t just a mental illness. This has spurred on another huge study to further investigate the genetic and metabolic links that could help improve treatment. Like I said earlier, current treatment usually ends up with a weight restoration target set too low so true restoration and brain healing doesn’t occur so the patient remains in an anorexic state.
Then there is a study from 2016 in Translational Psychiatry, which reported on mice with a variant in a gene that in people is linked to anorexia. On its own, the variant didn’t seem to make much of a difference in mouse behaviour, but when the mice were given diets restricting calories by 20%–30% and then subjected to stress which included isolation, they stopped eating. This research suggests that it is a combination of genetic and environmental risk factors that drives susceptibility to anorexia. It also goes a little way to contributing to explaining why the incidence of eating disorders in children and adolescents has risen during the pandemic. Isolation, plus genetics, plus weight loss for whatever reason etc etc.
Then there is research by Joanna Steinglass (also 2016) in the Journal of Eating Disorders that showed differences in MRI brain scans of people with eating disorders and those without. In people with anorexia, MRI scans revealed that the region of the brain associated with selecting foods was the dorsal striatum, which is a key region involved in forming habits. In people without an eating disorder, a different brain region is associated with food choices. This research showed that many symptoms of eating disorders have a neurobiological basis and are not just psychological, as many seem to think.
In 2020 a study in European ED’s Review showed the presence of typical neurodevelopmental patterns in anorexic patients and that severity of emaciation is related to brain morphology reductions, highlighting the importance of true weight restoration.
Various studies have also shown that genes contribute more than 50% to 74% of AN developing risk. All of this research clearly points to genetic, neurobiological, biochemical and psychiatric elements to the illness. It is not simply a mental illness. That is outdated thinking.
Do a pubmed, CINALH etc database search and you’ll easily find the plethora of current research into this element.[/quote]
👏🏻
Thank you.
There is so little understanding on this, I honestly think most people have no understanding that all it takes for a child to develop anorexia is genetics plus weight loss.
If they did they would not push calorie counting on to children.
It's probably easier to believe it's a mental health condition that is the result of trauma or abuse because that means their children are immune to it....