Me and DH both work full time with two children, primary age. The children go to wraparound and prior to that they went to nursery. I went back to work after a year mat leave each time.
It is hard, and as they get older it is getting harder as they have hobbies and clubs to go to as well as remembering which day this one has to bring swimming kit and which day that one has spelling test etc etc.
I think it's difficult to climb the ladder at work tbh, and I'm there full time. I'm too busy and stressed keeping all the balls in the air as it is, without taking on more - I'm relatively senior at work, but really should be taking the next step - but don't have the headspace at the moment.
Having said that, there is absolutely no way I would have given up work totally, and neither would my husband. When he got made redundant, it was a worry, but such a lot less of a worry as I was still earning and we know we could pay the bills until he got something else. Also, after seeing my mum get totally screwed over as a single parent as she'd given up work to raise kids...
My advice to anyone is always to go back full time and see how you feel. You can always drop down, but hard to get the days back once someone else has been employed to do them!
As for hobbies, I manage to get out for a run a few times a week and my DH has an exercise bike - we do a few things, but it's not a massive priority.
Totally agree with the pp who said you have to let things go a bit - our house is tidy and reasonably clean, but we never get round to DIY!