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Can you kill a cold before it takes?

105 replies

ShakyBake · 20/09/2026 21:10

Feel a bit sore throaty and that a cold is about to hit but also feel like it's not taken over yet, like I'm on top of it. Is it possible to actually fight a cold off before it fully takes?

Have been eating extra well with lots of veg and high quality protein and just had a fizzy vitimin. What else can I do?

OP posts:
MellowSubmarine · 21/09/2026 08:43

That’s a meta analysis of studies ranging 2-5 months, looking at people taking regular vitamin c. I was talking about the lack of evidence for the benefit of taking it once symptoms start.

BalakayAARon · 21/09/2026 08:51

AlphabetBird · 21/09/2026 07:56

Do a sinus rinse with salt and bicarbonate 3-4 times a day at the very first sign. It’s proven to reduce cold severity and duration by a few days. You’ll need a squirt bottle or a neti pot.

Yes, I agree. I use the Neilmed Sinus Rinse squeezy bottle, as much easier for me than a netipot. I also gargle with the leftover solution remaining in the bottle.

It didn't fully stop my recent oncoming cold, but it didn't take hold. Just a runny nose/ mild congestion.

Girlwithavibe · 21/09/2026 09:15

Decorhate · 20/09/2026 21:18

There is an over the nasal spray you can take which I have found effective. Called First Defence.

I used this once and my cold was the worst cold I ever had and lasted ages !!
I don't know why or how but never used it again
Edit spelling mistakes

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Girlwithavibe · 21/09/2026 09:20

Nasal rinsing morning and night with sterile salt water works wonders stops germs in your nose !! Also I srat drinking those fizzy tablet drinks from September to April with vitamins c and zinc

Morepositivemum · 21/09/2026 09:24

Just hydration, fruit, some honey or honey lozenges and paracetamol and I normally knock it on the head!

PurpleSlime · 21/09/2026 09:59

Another vote for Echinacea drops! I always used to have horrible colds/coughs all year round. I now usually only have one in the winter and even that clears up quickly. I take them at first sign of a cold which for me is sore throat and symptoms usually just go away.

TheEdgyMoose · 21/09/2026 15:37

Natsku · 21/09/2026 08:42

I do have my own private sauna

You are winning at life. I'm jealous!

TheEdgyMoose · 21/09/2026 15:55

JustLookingThanks · 21/09/2026 08:06

I'm not an expert, this is what I read.
Dr Lloyd-Jones explains: "The lung disease of COVID-19 is in the blood vessels, not in the airways. The virus enters the nose and replicates in the mouth. A single teaspoon of saliva contains 500 million copies of the virus. The virus could easily leak from your saliva into the blood vessels of the mouth, especially if you have gum disease or bleeding gums. The virus would then be passed directly to the lungs via the bloodstream exactly to the areas where it does the most damage. There are everyday oral hygiene steps which might reduce the virus in the mouth and saliva, and lower the risk of it spreading to the lungs."
Link to information
And the zinc is a one off dose.

It was an interesting hypothesis and some studies have showed that certain ingredients in mouthwash can kill the COVID virus in a test tube. But these results have not been replicated in a human body. Any reduction in viral load in the mouth is temporary at best and has no effect on the course of the illness.

Even a one off dose of zinc could cause issues. The recommended daily limit in the UK is 25mg so I would be cautious about recommending taking triple that.

Highonmyownsupply · 21/09/2026 15:59

MellowSubmarine · 20/09/2026 21:23

There’s no evidence that vitamin c taken at the first sign of a cold does anything at all.

Your best bet is rest and staying hydrated.

There’s a media report today confirming this. But, apparently there’s some evidence that gurgling with salt water and/or a nasal saline rinse helps. Can’t link to article as it’s behind a paywall.

Baublebonkers · 21/09/2026 16:07

Yes, I do it all the time with first defence nasal spray. As long as I catch it straight off it never develops.

mumumental · 21/09/2026 16:16

Highonmyownsupply · 21/09/2026 15:59

There’s a media report today confirming this. But, apparently there’s some evidence that gurgling with salt water and/or a nasal saline rinse helps. Can’t link to article as it’s behind a paywall.

It does help me. That saline water spray stuff Sterimar doesn’t stop mine but it does shorten them if I start on the stuff quickly.

TwigletTwig · 21/09/2026 16:23

I prefer Boots Dual Defence nasal spray rather than First Defence. It works well if I use it as soon as I feel a tickle in my nose.

Delatron · 21/09/2026 16:44

Yes I find the Boots own version of First Defence is less stingy. There’s also evidence that using a saline/sea water rinse or nasal spray can help.

I use before I get on airplanes (also a cream that you rub round the nose) and public transport and also after.

Both DH and DS had a cold this week and I managed to avoid (and I did get a tickle) with First Defence. I also had some Sambucol and propolis throat spray but don’t know how much they helped.

Rest is also hugely important if you feel like you are coming down with something.

DosPerros · 21/09/2026 17:07

I’m always starving when I’m feeling a cold coming on and only want to eat sweets! Sorry to say that I stuff myself with junk…..

Shinyhappyapple · 21/09/2026 17:23

Vick’s first defence nasal spray - use at first signs of a cold.
Effervescent vit c and zinc tablet in a glass of water
Lemsip drink

It’s the nasal spray that makes most difference though and I’ve read that even a plain saline spray can help, and can even be preventative.

LateMumma · 21/09/2026 17:39

Also vote for echinacea and first defense (or boots dual defense equally as effective) I also swear by a D3/K2 supplement year round

Natsku · 21/09/2026 17:39

TheEdgyMoose · 21/09/2026 15:37

You are winning at life. I'm jealous!

I am very happy that I have it, my whole childhood I wished we had one at home.

LastNightMyPJsSavedMyLife · 21/09/2026 17:54

Sleep

ginasevern · 21/09/2026 17:56

First Defence all the way.

SomeoneIsWrongOnTheInternet · 21/09/2026 18:01

I’m feeling pretty much the same! Sore throat, bit achy, tiring easily. I’m hitting it with everything, innocent smoothie (citrus defence is often on offer), garlic and ginger in stir fry and kiwi fruit. Here’s hoping!

Vivaldi85 · 21/09/2026 18:04

Raw grated ginger and tumeric with some lemon and honey in boiling water
Works every time .

muddyford · 21/09/2026 18:06

First Defence spray sees most of mine off.

Livpool · 21/09/2026 18:25

theturtleswims · 20/09/2026 21:31

Seconding this. It works for me too.

Agree - this is great. You have to take it super early yhough, at the very first sign or else too late.

TheEdgyMoose · 21/09/2026 18:32

Natsku · 21/09/2026 17:39

I am very happy that I have it, my whole childhood I wished we had one at home.

I used to work with someone who went to the steam room at the local gym every time she got a cold so I assumed the worst when I read your post. Sorry.

AnswerIsNo · 21/09/2026 19:10

Astragalus Root Extract 1-2 500mg caps- traditional TCM herb, but increasing research shows its role in upregulating and downregulating certain Interleukins, which are key in the immune response, especially inflammatory cytokines - which make you feel crap, achey and stupid

Beta Glucans 1-2 500mg tablets per day

Elderberry extract but the Sambucol liquid is so expensive and massively under-dosed, compared to something like 10:1 powder capsules

5000iu Liquid Vitamin D ideally in MCT oil for max bioavailability

The first two are immuno-stimulators and can definitely make you feel jittery at time - especially Astragalus. I combine these 2 for a time-limited treatment - in terms of preventing full onset or shift persistent colds, they have oomph that Echinacea lacks

The only issue is they are not clinically-approved or fully researched as of yet, but IME they are definitely more potent than Elderberry or Echinacea.

YMMV and a considered Risk - Reward ratio applies !

A Review of the Pharmacological Action of Astragalus Polysaccharide - PMC

Astragalus membranaceus (A. membranaceus) is a type of traditional Chinese medicine with a long history of clinical application. It is used in the improvement and treatment of various diseases as medicine and food to invigorate the spleen and ...

https://pmc.ncbi.nlm.nih.gov/articles/PMC7105737/

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