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Loving Sarah Vine on This Morning -Ozempic

252 replies

AmyFFowler · 15/05/2024 11:48

She said we live in an obesogenic society and need to be realistic about the need for weight loss drugs like ozempic. She also said we are genetically programmed to eat as much as possible when we can as our ancestors didn’t know when the next wilderbeast would come along. Now we can just sit in our house and deliveroo will bring us food.
Completely agree with all of the above. I am currently working very hard and managing to lose weight without the help of drugs, so I do also ‘get’ the personal responsibility side to this. I just think as a society we are fighting a losing battle if we don’t embrace the new wave of weight loss drugs. Hopefully in time there will be more studies into long term use.

OP posts:
soupfiend · 15/05/2024 21:13

CormorantStrikesBack · 15/05/2024 19:26

So does this show it’s more complicated than calories in vs calories burned? Assuming the same level of activity in your 50s vs 30s? Or is just due to less muscle mass meaning less calories burned?? Because i hear women who are still going to the gym in their 50s/still burning off the same amount of calories and eating the same saying this. Which suggests there’s a hormonal element?

You're not burning off the same amount of calories as you get older, thats the point!!! Thats why you cut your calorie intake to match your new outake, or do more exercise if possible, although personally that makes me ravenous.

bonzaitree · 15/05/2024 21:15

I take weight loss injections and I’ve found them revolutionary.

Ive always been starving tired and unhappy on a diet and god knows I’ve tried them all. I beat myself up over failing to stick to diets. I thought I was lazy demotivated stupid etc. Couldn’t understand how I’m smart and motivated in other areas of my life but when it came to nutrition I was a massive failure.

It wasn’t lack of education- I know exactly what I should eat. It wasn’t lack of money- I’m lucky and can buy whatever food I want. It wasn’t lack of cooking skills or organisation- I’m great at both. It wasn’t anything except being fucking starving all the time.

Since taking the injection I’ve found my weight has slowly and steadily decreased. Because I’m not starving 24/7 so I’m able to eat what I know I should be eating and stop when I’ve had enough.

But it’s more than that. I feel like my energy is much better throughout the day. I sleep better. My mood is better. Everything is just, somehow, better.

Is it pricy? Yes. But I’m lucky enough to afford it and it’s fucking worth it. Best thing I’ve done for myself bar my education.

C1nders · 15/05/2024 21:16

Put on a huge amount of weight through medication. Can’t lose weight on much more than around 800 calories. Have gone on wegovy privately.

Interested in this thread?

Then you might like threads about this subject:

Beepbird · 15/05/2024 21:17

Choux · 15/05/2024 21:02

Did you read this link? The abstract says that weight loss drugs have been used to... "improve glycemic control and cardiovascular outcomes among people with type 2 diabetes and a high cardiovascular risk"

BUT to identify patients with heart failure (which is a serious medical condition - my 83 year old dad died of it last year) they suggest performing screening and then, IF the patient has heart failure and IF they have a reduced ejection fraction (which is the heart not pushing out as much blood when it contracts), you should be cautious of using weight loss drugs as there have been many studies on how the drugs might affect their existing illness and could make it worse.

So for most people the drugs improve cardiovascular outcomes. For a small number of people already sick the need to be cautious is there isn't enough studies done yet and it MIGHT be a problem.

Full abstract text:
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been used to reduce body weight in overweight or people with obesity and to improve glycemic control and cardiovascular outcomes among people with type 2 diabetes (T2D) and a high cardiovascular risk. However, the effects of GLP-1 RAs may be modified by the presence of heart failure (HF). In this review, we summarize the evidence for the use of GLP-1 RA across a patient's risk with a particular focus on HF. After a careful review of the literature, we challenge the current views about the use of GLP-1 RAs and suggest performing active HF screening (with directed clinical history, physical examination, an echocardiogram, and natriuretic peptides) before initiating a GLP-1 RA. After HF screening, we suggest GLP-1 RA treatment decisions as follows: (1) in people with T2D without HF, GLP-1 RAs should be used for reducing the risk of myocardial infarction and stroke, with a possible effect to reduce the risk of HF hospitalizations; (2) in patients with HF and preserved ejection fraction, GLP-1 RAs do not reduce HF hospitalizations but may reduce atherosclerotic events, and their use may be considered in an individualized manner; and (3) in patients with HF and reduced ejection fraction, the use of GLP-1 RAs warrants caution due to potential risk of worsening HF events and arrhythmias, pending risk-benefit data from further studies.

@Choux Yes I read the abstract. And you are correct-the last part stating that there might be a link. That’s what good science looks like. We never talk in terms of absolutes, because in scientific terms, nothing is. All that we say is that things may or may not be xyz. And we look at the data to support a theory, or to not support it. Nothing is ‘proved’ and nothing is definitive. Not even something as universally accepted at Newton’s theory of gravity-there are some situations in which it doesn’t hold true. That doesn’t make it all rubbish, it just means there’s certain situations where it isn’t quite correct. And the job of scientists is to continually add data to increase our understanding of something. It’s not egotistical, or it shouldn’t be. It’s about the search for the truth.

AhBiscuits · 15/05/2024 21:19

I've been on Wegovy for just under 6 months and lost nearly 3 stone. I'm weaning off it now as I'm nearly at my goal weight. It's brilliant, I'd recommend it to anyone who struggles with their weight.

I think people are put off due to there being a stigma around it. They feel like it's cheating, losing weight is supposed to be a difficult battle, like a punishment for getting fat. You get one life and these drugs really are life changing for so many people.

Beepbird · 15/05/2024 21:20

One more thing to consider is how well the data has been statistically controlled to remove the effect of weight loss on cardiovascular health etc. As losing weight by whatever method will likely improve cardiovascular health. The danger is the media will spin it as it is the drugs themselves that are directly having that effect, rather than a consequence of weight loss.

soupfiend · 15/05/2024 21:20

Choux · 15/05/2024 20:44

There is research which shows metabolism in adults doesn't slow till the age of 60. Which goes against what most people believe and probably other studies.

www.health.harvard.edu/blog/surprising-findings-about-metabolism-and-age-202110082613

What I think people need to be aware of is declining activity levels as we age. And not big reductions. If you make a tiny change or two to how active you are, you might burn 50 calories a day less. You probably won't even realise you have done a bit less.

But if you do that for a year that's 365 x 50 = 18,250 calories burned in a year. If your eating remains exactly the same as before you will put on over 5lbs. Over a decade that's 50lbs weight gain coming from just a 50 calorie a day change. If you are getting into a habit of a biscuit or two with an afternoon tea on top of that the gain could be 150lbs over a decade. Yet we would say we still have the same activity levels and aren't really eating differently so it must be our metabolism.

I think that's where my weight gain came from.

I think personally it is younger because of menopause but your points about very small calorie excesses is absolutely right, its been said on many a thread and I do repeat this, someone did a calculation that you only need the equivalent calorie excess of a couple of biscuits per day to put on a stone a year.

You dont need to be a binger, a 'comfort eater' an 'emotional eater', to have disordered eating or anything like that to gain and gain and gain, add in menopause, or slowing down in life generally, perhaps you got to the stage where you bought a car or you moved somewhere without public transport so you drive everywhere routinely and it will pile on

Humans are geared to enjoy food, enjoy eating, seek out high calorie foods the combination of this and the way food is sold and packaged equals obesity.

ZestofCoffee · 15/05/2024 21:20

CormorantStrikesBack · 15/05/2024 21:10

Guess we all need to get weight lifting 💪😁

Absolutely- best way to maintain it 🏋🏼‍♀️ I am lucky that I love training. I know many don’t.

Scottishlanza · 15/05/2024 21:20

bonzaitree · 15/05/2024 21:15

I take weight loss injections and I’ve found them revolutionary.

Ive always been starving tired and unhappy on a diet and god knows I’ve tried them all. I beat myself up over failing to stick to diets. I thought I was lazy demotivated stupid etc. Couldn’t understand how I’m smart and motivated in other areas of my life but when it came to nutrition I was a massive failure.

It wasn’t lack of education- I know exactly what I should eat. It wasn’t lack of money- I’m lucky and can buy whatever food I want. It wasn’t lack of cooking skills or organisation- I’m great at both. It wasn’t anything except being fucking starving all the time.

Since taking the injection I’ve found my weight has slowly and steadily decreased. Because I’m not starving 24/7 so I’m able to eat what I know I should be eating and stop when I’ve had enough.

But it’s more than that. I feel like my energy is much better throughout the day. I sleep better. My mood is better. Everything is just, somehow, better.

Is it pricy? Yes. But I’m lucky enough to afford it and it’s fucking worth it. Best thing I’ve done for myself bar my education.

You could be me, everything you have said resonates

CormorantStrikesBack · 15/05/2024 21:22

ZestofCoffee · 15/05/2024 21:20

Absolutely- best way to maintain it 🏋🏼‍♀️ I am lucky that I love training. I know many don’t.

Same, I do 3hrs of weights most weeks. Plus spinning and cycling which although not weightlifting will help with muscle mass.

Aussieland · 15/05/2024 21:25

lljkk · 15/05/2024 13:30

Now we can just sit in our house and deliveroo will bring us food.

Well... yeah. You CAN. You can make other choices, though. You can go out & get your own shopping or go out & do FUN things or even active stuff.

Free will & self-determination and agency still exist.

Oh it must be lovely to have the time and emotional state to be able to make those choices. Perhaps imagine some people don’t have those opportunities.

or maybe some who DO make those choices and yet are still obese. I love the idea that all overweight people just sit at home stuffing their faces 24/7 and aren’t out for walks, making nutritious meals, doing active jobs. Some who do everything you judge to be the answer to weight loss and yet are still big.

User14March · 15/05/2024 21:25

@soupfiend your appetite doesn’t get memo though. You are still as hungry as you were before you needed far fewer calories.

ZestofCoffee · 15/05/2024 21:25

bonzaitree · 15/05/2024 21:15

I take weight loss injections and I’ve found them revolutionary.

Ive always been starving tired and unhappy on a diet and god knows I’ve tried them all. I beat myself up over failing to stick to diets. I thought I was lazy demotivated stupid etc. Couldn’t understand how I’m smart and motivated in other areas of my life but when it came to nutrition I was a massive failure.

It wasn’t lack of education- I know exactly what I should eat. It wasn’t lack of money- I’m lucky and can buy whatever food I want. It wasn’t lack of cooking skills or organisation- I’m great at both. It wasn’t anything except being fucking starving all the time.

Since taking the injection I’ve found my weight has slowly and steadily decreased. Because I’m not starving 24/7 so I’m able to eat what I know I should be eating and stop when I’ve had enough.

But it’s more than that. I feel like my energy is much better throughout the day. I sleep better. My mood is better. Everything is just, somehow, better.

Is it pricy? Yes. But I’m lucky enough to afford it and it’s fucking worth it. Best thing I’ve done for myself bar my education.

Im like this. I could eat and eat and eat. I used to run just to eat. I’d do a half marathon and be delighted I had an extra 1200 cals to scoff. Now I have a bad knee - so weight train and do HIIT but not sure I would if I was naturally slim.

I have read ozempic stops the “food noise” and that sounds like a dream.

I am a healthy weight but it’s a battle and if I could mute the “food noise” I would. The only reason I don’t is I believe I have nothing to gain (being healthy but, yeah, I’d love to drop 10lb) and more to lose - ie any unknown side effects.

The drug costs the same as PT… I can train by myself I pay for the accountability now.

Sorry to derail. It sounds too good to be true!!

ZestofCoffee · 15/05/2024 21:27

CormorantStrikesBack · 15/05/2024 21:22

Same, I do 3hrs of weights most weeks. Plus spinning and cycling which although not weightlifting will help with muscle mass.

Your heart is a muscle that needs training too 😃 I do the same spilt 💪🏼 3 weights, 2 HIIT or spin. Then some walking on the weights and rest days.

soupfiend · 15/05/2024 21:28

User14March · 15/05/2024 21:25

@soupfiend your appetite doesn’t get memo though. You are still as hungry as you were before you needed far fewer calories.

Yup. Although as most of us also know, we dont always eat because we are actually hungry, we eat because we want food. And for many of us, we get these uncontrollable (or what feel like uncontrollable) cravings, in my case certainly linked to things like bread, pasta, potato, rice (most of which I have cut out). The injections shut this down, the food noise as we say.

gingercat02 · 15/05/2024 21:32

User14March · 15/05/2024 20:33

@gingercat02 after 2 years what does not being as effective mean? Increasing patient doses? How do you mitigate? Thanks

Everyone would be titrated up to the full dose as required, but once the weight loss and improvement in diabetes stops or levels out, most people end up on insulin. You can take both, but most people don't.

soupdragon321 · 15/05/2024 21:34

As everyone here seems to know a lot about it, I’m just wondering if someone can answer a question for me. Does Ozempic etc make people lose weight simply by mimicking a ‘full’ signal and so you don’t eat much at all, or does it do something biologically to the body to make it lose weight? Just curious!

User14March · 15/05/2024 21:35

@soupfiend isn’t ‘food noise’ universal ? & if not, why not? Fascinating.

AhBiscuits · 15/05/2024 21:35

soupdragon321 · 15/05/2024 21:34

As everyone here seems to know a lot about it, I’m just wondering if someone can answer a question for me. Does Ozempic etc make people lose weight simply by mimicking a ‘full’ signal and so you don’t eat much at all, or does it do something biologically to the body to make it lose weight? Just curious!

It works by making you eat less in a few different ways. The drug itself does not cause weight loss.

DownWithThisKindOfThing · 15/05/2024 21:38

soupdragon321 · 15/05/2024 21:34

As everyone here seems to know a lot about it, I’m just wondering if someone can answer a question for me. Does Ozempic etc make people lose weight simply by mimicking a ‘full’ signal and so you don’t eat much at all, or does it do something biologically to the body to make it lose weight? Just curious!

I am on Mounjaro but for me what it does is:

make me feel fuller
make me feel less hungry
stop me having cravings so it’s easier to make better choices
if I do choose to eat something like crisps or chocolate I can be satisfied after 1 or 2 crisps or a square of chocolate. I don’t want more.
it stops me getting a “hit” from food

ZestofCoffee · 15/05/2024 21:39

soupdragon321 · 15/05/2024 21:34

As everyone here seems to know a lot about it, I’m just wondering if someone can answer a question for me. Does Ozempic etc make people lose weight simply by mimicking a ‘full’ signal and so you don’t eat much at all, or does it do something biologically to the body to make it lose weight? Just curious!

I listened to https://open.spotify.com/episode/3R9jH7gQxBstMtlxMoz2GL?si=KLZO5EiTTkOFFjGhAzXmVg
apparently stimulates the brain by mimicing the actions of the naturally-occurring GLP hormone associated with the feeling of satiety.

Spotify

https://open.spotify.com/episode/3R9jH7gQxBstMtlxMoz2GL?si=KLZO5EiTTkOFFjGhAzXmVg

User14March · 15/05/2024 21:41

@DownWithThisKindOfThing isn’t there a shortage of Mounjaro? Honestly, do you think many people feel like this about food, & find it that simple to control in the way you describe?

bonzaitree · 15/05/2024 21:46

ZestofCoffee · 15/05/2024 21:25

Im like this. I could eat and eat and eat. I used to run just to eat. I’d do a half marathon and be delighted I had an extra 1200 cals to scoff. Now I have a bad knee - so weight train and do HIIT but not sure I would if I was naturally slim.

I have read ozempic stops the “food noise” and that sounds like a dream.

I am a healthy weight but it’s a battle and if I could mute the “food noise” I would. The only reason I don’t is I believe I have nothing to gain (being healthy but, yeah, I’d love to drop 10lb) and more to lose - ie any unknown side effects.

The drug costs the same as PT… I can train by myself I pay for the accountability now.

Sorry to derail. It sounds too good to be true!!

It 100% stops the “food noise” ie the arguments in your head “no you’ve had enough” “no that’s not on plan” “well if I skip that snack maybe I can have x” “ how long until the next meal”

The constant push/ pull of your body and monkey brain wanting more and more but your logical side saying “no, no, no”

All gone.

Im not a doctor and I don’t know you but personally I’d say money is better spent on Ozempic than on a PT… you can still be active without the PT after all.

User2460177 · 15/05/2024 21:47

Limberinta · 15/05/2024 15:03

I've just highlighted that it's not a conspiracy theory. It's critical thinking. Other Dr's have been on TV if that's your preferred method of information saying what I just said. The information is there if you look for it. I also gave you the example of astrazeneca. So many 'trusted sources' saying its safe, it doesn't have related issues to blood clots, take it, take it, take it, it's safe. People made to feel like heretics for being sceptical and wary. Except it does and they've now admitted it. And withdrawn it from circulation. But it's so safe, right? Just think, really think about what you're told before accepting it.

I'm far from saying it might not have benefits. It might do. But no one knows what it does long term

I'm also not judging anyone for using it if they want to or feel they have no choice. I get it and people should do whatever they feel they need to. I just don't support the pharmaceutical company paid for studies being used to tell people it's so safe when nothing in its infancy is and they can choose to eliminate the negatives from their 'evidence' they publish to the public

Edited

It’s not “critical thinking” saying a drug causes heart attacks when it doesn’t. It’s just making stuff up. All evidence shows GLP weight loss drugs are very effective and don’t have serious side effects.

No one has “admitted” the Astra zeneca covid vaccine is dangerous. It’s been withdrawn because it’s less effective against new strains of Covid circulating than other vaccines.

ZestofCoffee · 15/05/2024 21:48

bonzaitree · 15/05/2024 21:46

It 100% stops the “food noise” ie the arguments in your head “no you’ve had enough” “no that’s not on plan” “well if I skip that snack maybe I can have x” “ how long until the next meal”

The constant push/ pull of your body and monkey brain wanting more and more but your logical side saying “no, no, no”

All gone.

Im not a doctor and I don’t know you but personally I’d say money is better spent on Ozempic than on a PT… you can still be active without the PT after all.

I am active without a PT, I’ve seen her a while now and am a proper gym bunny, love exercise, love working out. Just can’t stop the food noise! I just like someone texting me asking me if I’m on plan, checking my food diary etc. if I didn’t have the “good noise” I’d smash diet and exercise.

Did you just get it from a boots pharmacy or something?