And last night they aired an episode featuring an ambiguously gendered ten year old. The point was apparently supposed to be that it was no big deal whether this child was male or female, and the other kids were rude for wanting to know. They should all be happy to embrace this new classmate as an unknown, non-binary entity, who will presumably go by they / them forever.
This is inaccurate. Spoiler warning! For anyone who hasn't watched it yet.
The androgynous child was visiting the school to talk about a scouts type organisation called Webelos. During the 30 seconds total of screen time where this Webelo kid was talking to the class, Cartmen and the rest whispered a little (twice) about whether the Webelo kid was a boy or girl. The Webelo kid doesn't appear in the episode again.
Next scene the boys are in the playground discussing how sure they are the Webelo kid is a boy or girl which leads into the introduction of prediction market app betting.
The focus of the episode was split between taking the piss out of Trump with the storyline about his and Satan's pregnancy, and the storyline Cartman trying to manipulate the kids at school so he could make money on the prediction market app. His plan was to get Sheila Broflovski riled up, causing everyone else to bet using the app that she would bomb a Palestinian hospital, while he put a "safe" bet on that she wouldn't. She gets so angry with everyone asking what she intends to do about the situation in Gaza that she goes to Israel, causing Cartman to momentarily panic, but Sheila just wants to give Netanyahu a piece of her mind so it ends on Sheila giving an angry lecture.
There was nothing pandering to trans ideology in the episode.
It's not as funny as it used to be, but I thought it was still an enjoyable episode. I think it must be hard to do comedy like this these days when everything in real life is already so absurd.